Zobrazeno 1 - 10
of 88
pro vyhledávání: '"A. Ambrosetti"'
Autor:
Samantha Ferrari, L. Rigacci, Monia Capponi, Alessandro Pulsoni, Giuseppe Visani, Luca De Carolis, Pier Luigi Zinzani, Robin Foà, Paolo Falcucci, Enrico Tiacci, G. Gaidano, Eugenio Lucia, Agostino Antolino, Francesco Zaja, A. Ambrosetti, Stefano Ascani, Roberta Della Seta, Edoardo Simonetti, Natalia Frattarelli, Vincenzo Perriello, Brunangelo Falini
Publikováno v:
The New England journal of medicine. 384(19)
Hairy-cell leukemia (HCL) is a CD20+ indolent B-cell cancer in which a BRAF V600E kinase-activating mutation plays a pathogenetic role. In clinical trials involving patients with refractory or relapsed HCL, the targeting of BRAF V600E with the oral B
Autor:
Hervé Quintens, Mélanie Guyot, Florence Dupré, Jérôme Durivault, Jean-François Roussel, Damien Ambrosetti, Gilles Pagès, Renaud Grépin, Aurore Dumond
Publikováno v:
Theranostics
Metastatic clear cell renal cell carcinomas (mRCC) over-express the vascular endothelial growth factor (VEGF). Hence, the anti-VEGF antibody bevacizumab/Avastin (BVZ) combined with interferon alpha (IFN) was approved for the treatment of mRCC. Howeve
Autor:
François Sarasin, Alessandra Costanza, Edith Paula Meszaros, Catheline Stancu, Guido Bondolfi, Julia Ambrosetti, Marie Besson
Publikováno v:
BMC psychiatry, Vol. 21, No 1 (2021) P. 399
BMC Psychiatry, Vol 21, Iss 1, Pp 1-4 (2021)
BMC Psychiatry
BMC Psychiatry, Vol 21, Iss 1, Pp 1-4 (2021)
BMC Psychiatry
Background Antibiomania is a rare but recognized side effect with yet unclear definite pathogenesis although multiple hypotheses have been proposed. The novelty of this case is the suspected pharmacodynamic drug-drug interaction between clarithromyci
Autor:
Maeva Dufies, Alexandre Bozec, Frederic Luciano, Julie Rousset, Olivia Rastoin, Esma Saada-Bouzid, Damien Ambrosetti, Isabelle Bourget, Anais Hagege, Christopher Montemagno, Julien Boyer, Julien Parola, Gilles Pagès, Yihai Cao, Xingkang He
Publikováno v:
SSRN Electronic Journal.
Local or metastatic relapses following surgery, radiotherapy and chemotherapy (cisplatin) are the leading causes of death of patients with head and neck squamous cell carcinoma (HNSCC). In the current study, we showed that acquired resistance to radi
Autor:
Gallo M., Guarnotta V., De Cicco F., Rubino M., Faggiano A., Colao A., Albertelli M., Altieri B., Ambrosetti E., Bianchi A., Bottiglieri L., Campione S., Carra S., Di Dato C., DiMolfetta S., Di Sarno A., Fanciulli G., Ferone D., Ferrau F., Giannetta E., Grillo F., Grossrubatscher E. M., Guadagno E., Isidori A., Lo Calzo F., Malandrino P., Martini C., Messina E., Modica R., Muscogiuri G., Pizza G., Razzore P., Rizza L., Ruggeri R. M., Sciammarella C., Vitale G., Zatelli M. C.
Purpose: Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine carcinoma arising from the skin. We aimed to review and deal with some of the most relevant controversial topics on the correct use of immunotherapy for the treatment of MCC. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb63929e872b8e986bf72f9645c0440f
http://hdl.handle.net/11573/1413703
http://hdl.handle.net/11573/1413703
Autor:
Emmanuel Chamorey, Wilfried Souleyreau, Alain Ravaud, Xingkang He, Papa Diogop Ndiaye, Lindsay S. Cooley, Sandy Giuliano, Nathalie M. Mazure, Benoit Beuselinck, Jessica Zucman-Rossi, Damien Ambrosetti, Patrick Auberger, Anais Hagege, Nathalie Rioux-Leclercq, Renaud Schiappa, Julien Parola, Karim Bensalah, Delphine Borchiellini, Stéphanie Torrino, Gilles Pagès, Andreas Bikfalvi, Yihai Cao, Nicolas Nottet, Baharia Mograbi, Jean-Christophe Bernhard, Annelies Verbiest, Maeva Dufies
Publikováno v:
Communications Biology
Communications Biology, 2021, 4 (1), ⟨10.1038/s42003-021-01653-w⟩
Communications Biology, Nature Publishing Group, 2021, 4, ⟨10.1038/s42003-021-01653-w⟩
Communications Biology, Nature Publishing Group, 2021, 4 (1), ⟨10.1038/s42003-021-01653-w⟩
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Communications Biology, 2021, 4, ⟨10.1038/s42003-021-01653-w⟩
Communications Biology, 2021, 4 (1), ⟨10.1038/s42003-021-01653-w⟩
Communications Biology, Nature Publishing Group, 2021, 4, ⟨10.1038/s42003-021-01653-w⟩
Communications Biology, Nature Publishing Group, 2021, 4 (1), ⟨10.1038/s42003-021-01653-w⟩
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Communications Biology, 2021, 4, ⟨10.1038/s42003-021-01653-w⟩
Polo-like kinase 1 (Plk1) expression is inversely correlated with survival advantages in many cancers. However, molecular mechanisms that underlie Plk1 expression are poorly understood. Here, we uncover a hypoxia-regulated mechanism of Plk1-mediated
Autor:
Sandy Giuliano, Nicolas Nottet, Wilfried Souleyreau, Papa Diogop Ndiaye, Damien Ambrosetti, Alain Ravaud, Maeva Dufies, Patrick Auberger, Julien Viotti, Anais Hagege, Emmanuel Chamorey, Stéphanie Torrino, Baharia Mograbi, Annelies Verbiest, Jean-Christophe Bernhard, Xingkang He, Yihai Cao, Jessica Zucman-Rossi, Andreas Bikfalvi, Gilles Pagès, Julien Parola, Nathalie M. Mazure, Benoit Beuselinck, Delphine Borchiellini, Lindsay S. Cooley, Karim Bensalah, Nathalie Rioux-Leclercq, Renaud Schiappa
Polo-Like Kinase 1 (Plk1) expression is inversely correlated with survival advantages in many cancers. However, molecular mechanisms that underlie Plk1 expression are poorly understood. Here, we uncover a novel hypoxia-regulated mechanism of Plk1-med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c906a1637dee59291ca39f25dcda0c
https://doi.org/10.1101/2020.02.05.20020552
https://doi.org/10.1101/2020.02.05.20020552
Autor:
Mazure, Nathalie M, Fabbri, Lucilla, Dufies, Maeva, Lacas-Gervais, Sandra, Gardie, Betty, Gad-Lapiteau, Sophie, Parola, Julien, Nottet, Nicolas, Meyenberg Cunha de Padua, Monique, Contenti, Julie, Borchiellini, Delphine, Ferrero, Jean-Marc, Leclercq, Nathalie Rioux, Ambrosetti, Damien, Mograbi, Baharia, Richard, Stéphane, Viotti, Julien, Chamorey, Emmanuel, Sadaghianloo, Nirvana, Rouleau, Matthieu, Craigen, William, Mari, Bernard, Clavel, Stéphan, Pagès, Gilles, Pouysségur, Jacques, Bost, Frédéric, Mazure, Nathalie
Publikováno v:
Theranostics
Theranostics, Ivyspring International Publisher, 2020, 10 (6), pp.2696-2713. ⟨10.7150/thno.41001⟩
Theranostics, 2020, 10 (6), pp.2696-2713. ⟨10.7150/thno.41001⟩
Theranostics, Ivyspring International Publisher, 2020, 10 (6), pp.2696-2713. ⟨10.7150/thno.41001⟩
Theranostics, 2020, 10 (6), pp.2696-2713. ⟨10.7150/thno.41001⟩
International audience; Rationale: Renal cell carcinoma (RCC) accounts for about 2% of all adult cancers, and clear cell RCC (ccRCC) is the most common RCC histologic subtype. A hallmark of ccRCC is the loss of the primary cilium, a cellular antenna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9c43ef1acea5eae482c94bbff7a383
https://hal.archives-ouvertes.fr/hal-03034269
https://hal.archives-ouvertes.fr/hal-03034269
Autor:
Juan L Iovanna, Christopher Montemagno, Olivia Rastoin, Anais Hagege, Emmanuel Chamorey, Gilles Pagès, Damien Ambrosetti, Maeva Dufies, Jean-Marc Ferrero, Sylvie Negrier, Nathalie Rioux-Leclercq, Brice Thamphya, Camillo Porta, Delphine Borchiellini
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Oncoimmunology
article-version (VoR) Version of Record
Oncoimmunology
article-version (VoR) Version of Record
Metastatic clear cell renal cell carcinoma (mccRCC) benefits from several treatment options in the first-line setting with VEGFR inhibitors and/or immunotherapy including anti-PD-L1 or anti-PD1 agents. Identification of predictive biomarkers is highl
Autor:
Roberto F E Pedretti, Ferdinando Varbella, Domenico Gabrielli, Alessio La Manna, Emilia Chiuini, Federico Nardi, Giovanni Battista Zito, Pompilio Faggiano, Alfredo Marchese, Fortunato Scotto di Uccio, Carmine Riccio, Marco Ambrosetti, Aldo P. Maggioni, Massimo Piredda, F. Massari, Roberta Rossini, Maurizio Giuseppe Abrignani, Nadia Aspromonte, Roberto Caporale, Stefano Urbinati, Giancarlo Casolo, Gian Francesco Mureddu, Andrea Di Lenarda, Leonardo De Luca, Michele Massimo Gulizia, Enrico Pusineri, Antonio Vittorio Panno, Giovanna Geraci, Furio Colivicchi, Giuseppe Musumeci, Gabriella Barile
Publikováno v:
European Heart Journal Supplements : Journal of the European Society of Cardiology
Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 receptor inhibitor is the cornerstone of pharmacologic management of patients with acute coronary syndrome (ACS) and/or those receiving coronary stents. Long-term (>1 year) DAPT may further re