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Publikováno v:
Current Pharmaceutical Design. 28:324-330
Background:Oxandrolone is a synthetic testosterone analogue that is widely used among bodybuilders and athletes. However, oxandrolone causes male infertility. Recently, it was found that metformin reduces the risk of infertility associated with diabe
Autor:
Kazuhiko Shibata, Takahiro Niimura, Mami Uchida, Noriaki Hidaka, Yoshihisa Kitamura, Kenshi Takechi, Keisuke Ishizawa, Hiroyuki Namba, Mamoru Tanaka, Hitoshi Kawazoe, Hiromu Kawasaki, Soichiro Ushio, Toshiaki Sendou, Yoshito Zamami, Akihiro Tanaka, Shingo Takatori, Hiroaki Araki
Publikováno v:
Biological and Pharmaceutical Bulletin. 45:226-234
Oxaliplatin (OXA) is used in chemotherapy for various cancer types and is associated with acute and chronic neurotoxicity. However, a preventive strategy for OXA-induced peripheral neuropathy (OIPN) and its underlying mechanism remain unclear. We exa
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 3, p e0193853 (2018)
PLoS ONE, Vol 13, Iss 3, p e0193853 (2018)
17β-estradiol treatment has shown benefit against schizophrenia symptoms, however longterm use may be associated with negative side-effects. Selective estrogen receptor modulators, such as raloxifene and tamoxifen, have been proposed as suitable alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::011797b2121308140f7e5e9e0a964b89
Publikováno v:
Brazilian Journal of Cardiovascular Surgery v.37 n.6 2022
Brazilian Journal of Cardiovascular Surgery
Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV)
instacron:SBCCV
Brazilian Journal of Cardiovascular Surgery n.ahead 2021
Revista Brasileira de Cirurgia Cardiovascular
Brazilian Journal of Cardiovascular Surgery (2021)
Brazilian Journal of Cardiovascular Surgery, Volume: 37, Issue: 6, Pages: 843-847, Published: 15 DEC 2021
Brazilian Journal of Cardiovascular Surgery, Issue: ahead, Published: 15 DEC 2021
Brazilian Journal of Cardiovascular Surgery
Sociedade Brasileira de Cirurgia Cardiovascular (SBCCV)
instacron:SBCCV
Brazilian Journal of Cardiovascular Surgery n.ahead 2021
Revista Brasileira de Cirurgia Cardiovascular
Brazilian Journal of Cardiovascular Surgery (2021)
Brazilian Journal of Cardiovascular Surgery, Volume: 37, Issue: 6, Pages: 843-847, Published: 15 DEC 2021
Brazilian Journal of Cardiovascular Surgery, Issue: ahead, Published: 15 DEC 2021
Introduction: To clarify the potential protective role of cilostazol on rat myocardial cells with ischemia-reperfusion injury (IRI) models. Methods: The study was conducted with three groups of 10 Wistar rats (control group, rats without any coronary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8427fdc9d6b7d5d08875b1d936dc3d
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382022000600843
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382022000600843
Publikováno v:
Diabetes & Metabolism Journal, Vol 46, Iss 1, Pp 117-128 (2022)
Background: It is unclear whether glycemic variability (GV) is a risk factor for diabetic peripheral neuropathy (DPN), and whether control of GV is beneficial for DPN. The purpose of this study was to investigate the effect of GV on peripheral nerve
Autor:
Masashi Takaso, Manabu Mukai, Ken Sugo, Ken Urabe, Takehiko Nakajima, Ken Takata, Kentaro Uchida, Masanori Nakasu
Publikováno v:
Bio-Medical Materials and Engineering. 33:41-50
BACKGROUND: Periprosthetic joint infection is a major complication of total joint arthroplasty, with treatment requiring a two-stage exchange procedure and 6 weeks of systemic antibiotics. However, depending on the infection site, intravenous deliver
Autor:
Wenxiu Zhang, Qichao Wu, Shuo Yuan, Yan Zhang, Lei Zang, Yanjun Zhang, Wenkai Zhang, Xueming Chen
Publikováno v:
Journal of Molecular Neuroscience. 72:730-740
After spinal cord injury (SCI), emergency treatment intervention can minimize tissue damage, which is closely related to the recovery of long-term function. Here, we examined whether the administration of a single dose of riluzole (6 mg/kg) immediate
Publikováno v:
Neurosci Biobehav Rev
Attention deficit hyperactivity disorder (ADHD) is a polygenic neurodevelopmental disorder that affects 8-12 % of children and4 % of adults. Environmental factors are believed to interact with genetic predispositions to increase susceptibility to ADH
Autor:
Wafaa, Mansour, Manal, Kamel, Emad, Elzayat, Shimaa, Atta, Dalia, Mahmood, Hanaa, Abd El Fattah El Sayed, Taghreed, Hussein, Sara, Saber
Publikováno v:
Experimental and Clinical Transplantation. 20:62-68
Objectives Hepatocellular carcinoma is the fourth leading cause of cancer deaths in the world. Conventional methods of cancer therapy are either invasive or have undesirable side effects. Therefore, exploring new therapeutic strategies to control the
Autor:
Zhe Wang, Bin Cheng, Jian-Min Lv, Shang-Rong Ji, Xiao-Ling Liu, Hai-Yun Li, Zhao-Ming Tang, Yi Wu, Yu-Lin Liang, Ning Gao
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 289-307 (2022)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background and aims C-reactive protein (CRP) is a hepatocyte-produced marker of inflammation yet with undefined function in liver injury. We aimed to examine the role of CRP in acetaminophen-induced liver injury (AILI). Methods The effects of CRP in