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Publikováno v:
Neurourology and Urodynamics. 38:2112-2120
Aims The goal of this study was to test whether central corticotropin-releasing factor (CRF) was involved in angiotensin II (Ang II) and Ang II type 1 (AT1) receptor-mediated facilitation of micturition reflex and to investigate whether peripherally
Autor:
Guo-Fang Xue, Dongfang Li, Miao-Jing Tian, Ru-Lin Mi, Zhen-Yu Yuan, Rui-Fang Wang, Christian Hölscher
Publikováno v:
Epilepsy Research. 154:97-106
Aims Glia-mediated neuro-inflammation and oxidative stress-induced neuronal apoptosis can contribute to epileptogenesis. We have demonstrated previously that mimetics of glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (G
Publikováno v:
Brain Research. 1715:41-46
Arginine-vasopressin (AVP) is believed to be positively correlated with the brain edema formation, but the underlying mechanism is still unclear. In this study, we explored the role of the V2 receptors antagonist tolvaptan on brain edema following in
Autor:
José Cipolla-Neto, Solange Castro Afeche, Paulo Flavio Silveira, Rafael Peres, Mariana Vieira Abrahão, Natália Fernanda Teixeira dos Santos, Ovidiu Baltatu, Wilson Mitsuo Tatagiba Kuwabara, Rafaela Fadoni Alponti Vendrame, Fernanda Gaspar do Amaral, Daniella do Carmo Buonfiglio
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
A local renin-angiotensin system (RAS) has been postulated in the pineal gland. In addition to angiotensin II (Ang II), other active metabolites have been described. In this study, we aimed to investigate a role for Ang IV in melatonin synthesis and
Publikováno v:
Neurourology and Urodynamics. 38:393-397
AIMS The goal of this study was to determine whether aging effects the expression of V1a and V2 vasopressin receptors in the urinary bladder mucosa (UBM) and kidney. METHODS UBM and kidneys were obtained from young (3 months-of-age) and old (25-30 mo
Publikováno v:
Pain
Opioids are the frontline analgesics in pain management. However, chronic use of opioid analgesics causes paradoxical pain that contributes to the decrease of their efficacy in pain control and the escalation of dose in long-term management of pain.
Autor:
Joice Maria da Cunha, Karina Genaro, José Alexandre de Souza Crippa, Janaina Menezes Zanoveli, Yane Costa Chaves
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Cannabidiol (CBD), a phytocannabinoid compound, presents antidepressant and anxiolytic-like effects in the type-1 diabetes mellitus(DM1) animal model. Although the underlying mechanism remains unknown, the type-1A serotonin receptor (5-HT1A) and cann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af411b495fa9fe3d21b91a0e055f8391
Autor:
Árpád Párdutz, Eleonóra Spekker, Annamária Fejes-Szabó, László Vécsei, Zsuzsanna Bohár, Klaudia Flóra Laborc, Mónika Szűcs, Gábor Nagy-Grócz
Publikováno v:
The Journal of Headache and Pain
The Journal of Headache and Pain, Vol 22, Iss 1, Pp 1-14 (2021)
The Journal of Headache and Pain, Vol 22, Iss 1, Pp 1-14 (2021)
Background The topical inflammatory soup can model the inflammation of the dura mater causing hypersensitivity and activation of the trigeminal system, a phenomenon present in migraineurs. Calcitonin gene-related peptide, transient receptor potential
Publikováno v:
Neurourology and urodynamicsREFERENCES. 40(1)
Aim Succinate activates the receptor GPR91 identified in the bladder. The present study aims to unravel the mechanisms of bladder relaxation by succinate and how the receptor is involved in structural and functional changes of the bladder. Methods Ph
Publikováno v:
Pain
Luminal distension and abdominal pain are major clinical hallmarks of obstructive bowel disorders and functional bowel disorders linked to gut dysbiosis. Our recent studies found that chronic lumen distension increased visceral sensitivity and decrea