Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Hans M.G. Princen"'
Autor:
Marta Iruarrizaga-Lejarreta, Anita M. van den Hoek, Elsbet J. Pieterman, José W.A. van der Hoorn, Lars Verschuren, David A. Fraser, Tore Skjaeret, Hans M.G. Princen, Cristina Alonso
Publikováno v:
Hepatology Communications, Vol 4, Iss 2, Pp 193-207 (2020)
Hepatology Communications
Hepatology Communications
Icosabutate is a structurally engineered eicosapentaenoic acid derivative under development for nonalcoholic steatohepatitis (NASH). In this study, we investigated the absorption and distribution properties of icosabutate in relation to liver targeti
Autor:
Tsai-Sang Dederichs, Peter Kohl, Katja Krebs, Clinton S. Robbins, Dennis Wolf, Bianca Dufner, Jiadai Zou, E.J. Pieterman, Timo Heidt, Christopher Starz, Rafael Kaeser, Natalie Hoppe, Peter Stachon, Tobias Boettler, Carmen Härdtner, Benoît Ho-Tin-Noé, Hans M.G. Princen, Florian Willecke, Andreas Zirlik, Diana Sharipova, Carolin A. Ehlert, Filip K. Swirski, Constantin von zur Mühlen, Alina Jander, Ingo Hilgendorf, Christoph Bode, Josef Madl, Simon Rauterberg, Jan Kornemann
Publikováno v:
Basic Research in Cardiology
Statins induce plaque regression characterized by reduced macrophage content in humans, but the underlying mechanisms remain speculative. Studying the translational APOE*3-Leiden.CETP mouse model with a humanized lipoprotein metabolism, we find that
Autor:
André Rex, Vincent Prinz, Dieter Lütjohann, Paul Fischer, Matthias Endres, Marco Foddis, Frieder Schlunk, Ulrich Laufs, Hans M.G. Princen
Publikováno v:
Stroke. 51
Autor:
A.E. Kozijn, Reinout Stoop, Yvonne van Gemert, N. Kruisbergen, Peter L E M van Lent, Harrie Weinans, Martijn H J van den Bosch, E.J. Pieterman, Arjen B. Blom, Marianne G. Pouwer, Hans M.G. Princen
Publikováno v:
Cartilage, synovium and bone.
Background High systemic cholesterol levels have been associated with osteoarthritis (OA) development and lowering cholesterol using statins has been suggested as a potential treatment for OA1. Recently, novel therapeutic high-intensive cholesterol-l
Autor:
Andrea D. van Dam, Joanne Verheij, Louis M. Havekes, José W.A. van der Hoorn, Lars Verschuren, Wen Liang, Petra Mulder, Robert Kleemann, Anita M. van den Hoek, Hans M.G. Princen, Mariëtte R. Boon
Publikováno v:
British Journal of Pharmacology. 172:5293-5305
BACKGROUND AND PURPOSE: Salsalate (salicylsalicylic acid) is an anti-inflammatory drug that was recently found to exert beneficial metabolic effects on glucose and lipid metabolism. Although its utility in the prevention and management of a wide rang
Autor:
Ruan Kruger, Alexander Bollenbach, Jean-François Huneau, François Mariotti, Vu Vi Pham, T Arndt, Jimmy F.P. Berbée, Jürgen C. Frölich, Sigurd Lenzen, Stefan Ückert, Thomas Lücke, Dirk Wedekind, Kristine Chobanyan-Jürgens, Hans M.G. Princen, Erik Hanff, Anne Jörns, Dimitrios Tsikas
Publikováno v:
Amino Acids, 7, 50, 799-821
Amino Acids
Amino Acids, Springer Verlag, 2018, 50 (7), pp.799-821. ⟨10.1007/s00726-018-2573-z⟩
Amino Acids, 50(7), 799-821
Amino Acids
Amino Acids, Springer Verlag, 2018, 50 (7), pp.799-821. ⟨10.1007/s00726-018-2573-z⟩
Amino Acids, 50(7), 799-821
International audience; We recently found that renal carbonic anhydrase (CA) is involved in the reabsorption of inorganic nitrite (NO2−), an abundant reservoir of nitric oxide (NO) in tissues and cells. Impaired NO synthesis in the endothelium and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ef1902d73d41bc5a8dd0f30cee9bcc
http://resolver.tudelft.nl/uuid:7d60b1b5-28ff-43d8-b95e-4fcdac7a6e0c
http://resolver.tudelft.nl/uuid:7d60b1b5-28ff-43d8-b95e-4fcdac7a6e0c
Autor:
Elsbet H. Pieterman, Hans M.G. Princen, Andrea D. van Dam, Patrick C.N. Rensen, Jimmy F.P. Berbée, Eveline Gart, Yanan Wang, Isabel M. Mol, Albert K. Groen, Henk G. Klop, Geerte Hoeke, Susan M. van den Berg, Mariëtte R. Boon
Publikováno v:
Atherosclerosis, 267, 116-126. Elsevier Ireland Ltd
Atherosclerosis, 267, 116-126
ATHEROSCLEROSIS, 267, 116-126. ELSEVIER IRELAND LTD
Atherosclerosis, 267, 116-126
ATHEROSCLEROSIS, 267, 116-126. ELSEVIER IRELAND LTD
Background and aims: Activation of brown adipose tissue (BAT) reduces both hyperlipidemia and atherosclerosis by increasing the uptake of triglyceride-derived fatty acids by BAT, accompanied by formation and clearance of lipoprotein remnants. We test
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e4e09c990fbeeb1e6bf67c481d4b50d
http://resolver.tudelft.nl/uuid:90ba63af-b55b-4f42-9ad0-1665c007760e
http://resolver.tudelft.nl/uuid:90ba63af-b55b-4f42-9ad0-1665c007760e
Autor:
N. Worms, Viktoria Gusarova, Hans M.G. Princen, N. Keijzer, Marianne G. Pouwer, J. Gromada, Joop Jukema, E.J. Pieterman
Publikováno v:
Atherosclerosis. 287:e12
Autor:
Hans M.G. Princen, Patrick C.N. Rensen, Willeke de Haan, Menno Hoekstra, Marit Westerterp, Johannes A. Romijn, Louis M. Havekes, J. Wouter Jukema, Caroline C. van der Hoogt, Geesje M. Dallinga-Thie
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 8, Pp 1763-1771 (2007)
Journal of lipid research, 48(8), 1763-1771. American Society for Biochemistry and Molecular Biology Inc.
Journal of lipid research, 48(8), 1763-1771. American Society for Biochemistry and Molecular Biology Inc.
In addition to efficiently decreasing VLDL-triglycerides (TGs), fenofibrate increases HDL-cholesterol levels in humans. We investigated whether the fenofibrate-induced increase in HDL-cholesterol is dependent on the expression of the cholesteryl este
Autor:
Mark V. Boekschoten, Corina J. A. Moen, Martijn B. Katan, David D. Moore, J. Gordon Porter, Arja J. Kreeft, Marten H. Hofker, Michael Müller, Soemini Kasanmoentalib, Rune R. Frants, S.M. Post, Marie-Louise Ricketts, Guido J. E. J. Hooiveld, Hans M.G. Princen
Publikováno v:
Molecular endocrinology, 21(7), 1603-1616. ENDOCRINE SOC
Molecular endocrinology, 21(7), 1603-1616
Molecular Endocrinology, 21(7), 1603-1616. The Endocrine Society
Molecular endocrinology 21 (2007) 7
Ricketts, M L, Boekschoten, M V, Kreeft, A J, Hooiveld, G J, Moen, C J, Müller, M, Frants, R R, Kasanmoentalib, S, Post, S M, Princen, H M G, Porter, J G, Katan, M B, Hofker, M H & Moore, D D 2007, ' The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane x receptors ', Molecular Endocrinology, vol. 21, no. 7, pp. 1603-1616 . https://doi.org/10.1210/me.2007-0133
Molecular Endocrinology, 21(7), 1603-1616. Endocrine Society
Molecular endocrinology, 21(7), 1603-1616
Molecular Endocrinology, 21(7), 1603-1616. The Endocrine Society
Molecular endocrinology 21 (2007) 7
Ricketts, M L, Boekschoten, M V, Kreeft, A J, Hooiveld, G J, Moen, C J, Müller, M, Frants, R R, Kasanmoentalib, S, Post, S M, Princen, H M G, Porter, J G, Katan, M B, Hofker, M H & Moore, D D 2007, ' The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane x receptors ', Molecular Endocrinology, vol. 21, no. 7, pp. 1603-1616 . https://doi.org/10.1210/me.2007-0133
Molecular Endocrinology, 21(7), 1603-1616. Endocrine Society
Cafestol, a diterpene present in unfiltered coffee brews such as Scandinavian boiled, Turkish, and cafetiere coffee, is the most potent cholesterol-elevating compound-knownin the human diet. Several genes involved in cholesterol homeostasis have prev