Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Xiaohe Wang"'
Autor:
Amy C. H. Lee, Fei Liu, Angela M. Lam, Andrea Cuconati, Bruce D. Dorsey, Xiaohe Wang, Rene Rijnbrand, Andrew G. Cole, Chen Shuai, Gotchev Dimitar B, Holly M. Micolochick Steuer, Steven G. Kultgen, Michael J. Sofia, Min Gao, Bailey Lauren Danielle, Fang Guo, Andrew S. Kondratowicz, Angela Miller
Publikováno v:
Journal of Virology
Noncanonical poly(A) polymerases PAPD5 and PAPD7 (PAPD5/7) stabilize HBV RNA via the interaction with the viral post-transcriptional regulatory element (PRE), representing new antiviral targets to control HBV RNA metabolism, HBsAg production and vira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b25564bc2473a1867029e3339bb3c92f
https://doi.org/10.1101/2021.04.12.439580
https://doi.org/10.1101/2021.04.12.439580
Autor:
Gotchev Dimitar B, Timothy M. Block, Tianlun Zhou, Xiaohe Wang, Jeffrey D. Branson, Rene Rijnbrand, Tim T. Chiu, Michael J. Sofia, Chris B. Moore, Fang Guo, Hongyan Liang, Troy Harasym, Bruce D. Dorsey, Min Gao, Siddhartha Rawat, Amy C.H. Lee, Liren Sun, Bailey Lauren Danielle, Fei Liu, Andy Cuconatti, Holly M. Micolochick Steuer, Andrew S. Kondratowicz
Publikováno v:
Antiviral Research. 149:191-201
In pursuit of novel therapeutics targeting the hepatitis B virus (HBV) infection, we evaluated a dihydroquinolizinone compound (DHQ-1) that in the nanomolar range reduced the production of virion and surface protein (HBsAg) in tissue culture. This co
Autor:
Richeng Mao, Bruce D. Dorsey, Andrew G. Cole, Quanxin Long, Alice H. L. Li, Sunny Tang, Rene Rijnbrand, Troy Harasym, Ellen Evangelista, Xiaohe Wang, Nicholas M. Snead, Kevin McClintock, Sara A. Majeski, Haitao Guo, Nagraj Mani, Kyle D. Cobarrubias, Stephen P. Reid, Fang Guo, Holly M. Micolochick Steuer, Janet R. Phelps, Steven G. Kultgen, Andrea Cuconati, Ju-Tao Guo, Qiong Zhao, Amy C.H. Lee, Salam Kadhim, Kim Stever, Kristi Fan, Andrzej Ardzinski, Michael J. Sofia
Publikováno v:
Antimicrobial Agents and Chemotherapy. 62
AB-423 is a member of the sulfamoylbenzamide (SBA) class of hepatitis B virus (HBV) capsid inhibitors in phase 1 clinical trials. In cell culture models, AB-423 showed potent inhibition of HBV replication (50% effective concentration [EC 50 ] = 0.08
Autor:
Dawei Cai, Richeng Mao, Yuanjie Liu, Changhua Ji, Ran Yan, Haitao Guo, Xiaohe Wang, Andrea Cuconati
Publikováno v:
Antiviral research. 132
Hepatitis B virus (HBV) covalently closed circular (ccc) DNA is essential to the virus life cycle, its elimination during chronic infection is considered critical to a durable therapy but has not been achieved by current antivirals. Despite being ess
Autor:
Scott Millhouse, Nigel W. Fraser, Xianchao Zhang, Benjamin P. Song, Xiaohe Wang, Ying-Hsiu Su, Timothy M. Block, Emily Oppenheim, Li Zhu
Publikováno v:
Journal of Neurovirology. 16:384-398
Using polymerase chain reaction (PCR) and alkaline gel electrophoresis, the authors show that, compared with DNA derived from virions used to establish infection, herpes simplex virus DNA derived from quiescently infected rat pheochromocytoma (PC12)
Autor:
Tianlun Zhou, Selena Y. Lin, Xiaohe Wang, Xiangdong David Ren, Ying-Hsiu Su, Timothy M. Block
Publikováno v:
Journal of Virological Methods. 158:24-29
The 1762T/1764A double mutation of the hepatitis B virus (HBV) basal core promoter has been suggested to be a potential biomarker for hepatocellular carcinoma (HCC) among individuals with chronic HBV infection. In this study, a real-time PCR assay is
Publikováno v:
Journal of Virology. 80:11589-11597
Following infection, the physical state of linear herpes simplex virus (HSV) genomes may change into an “endless” or circular form. In this study, using Southern blot analysis of the HSV genome, we provide evidence that immediate-early protein IC
Autor:
Nagraj Mani, Andrzej Ardzinski, S. Reid, T.O. Harasym, Amy C.H. Lee, E. Evangelista, A. Cole, S. Tang, A.H.L. Li, S. Majeski, B.D. Dorsey, Xiaohe Wang, S. Kadhim, Michael J. Sofia, Rene Rijnbrand, Andrea Cuconati, K. Cobarrubias, H. Liang, K. Mcclintock, J.R. Phelps
Publikováno v:
Journal of Hepatology. 64:S392-S393
Autor:
Xiaohe Wang, Yuk Ying Tung, Ying Hsiu Su, Ping Ling, Shih Heng Chen, Shun Hua Chen, Hui Wen Yao, Wen Yen Huang
Publikováno v:
The Journal of general virology. 91(Pt 3)
Acyclovir (ACV)-resistant herpes simplex virus type 1 (HSV-1) causes severe diseases in immunocompromised patients, so identification of new therapies is needed. Interferons (IFNs) are used to treat several other viral infections in the clinic, and I