Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Takeshi Iwaya"'
Autor:
Tomoko Takahashi, Takeshi Iwaya, Takashi Tokino, Satoshi Nishizuka, Yuji Akiyama, Tomomi Hirano, Masashi Idogawa, Yasushi Sasaki, Masakazu Abe, Fumitaka Endo, Akira Sasaki, Hayato Hiraki, Yuka Koizumi, Noriyuki Sasaki, Fumiaki Takahashi, Ryosuke Fujisawa, Shoichiro Tange, Mari Masuda, Mizunori Yaegashi
Publikováno v:
Carcinogenesis. 42:1239-1249
PurposeWe investigated whether early circulating tumor DNA (ctDNA) changes, measured using digital PCR (dPCR), can predict later chemotherapy responses in esophageal squamous cell cancer (ESCC).DesignWe compared the dynamics of ctDNA and tumor volume
Autor:
Doris R. Siwak, Toshimoto Kimura, Kei Sato, Hidewaki Nakagawa, Takeshi Iwaya, Masashi Fujita, Noriyuki Sasaki, Lance A. Liotta, Satoshi Nishizuka, Fumitaka Endo, Yiling Lu, Tsuyoshi Hachiya, Mizunori Yaegashi, Koki Otsuka, Tamotsu Sugai, Gordon B. Mills, Ryo Sugimoto, Zhenlin Ju
Publikováno v:
British Journal of Cancer
Background Circulating tumour DNA (ctDNA) is known as a tumour-specific personalised biomarker, but the mutation-selection criteria from heterogeneous tumours remain a challenge. Methods We conducted multiregional sequencing of 42 specimens from 14 c
Autor:
Doris R. Siwak, Hidewaki Nakagawa, Takehiro Chiba, Lance A. Liotta, Zhenlin Ju, Mizunori Yaegashi, Tsuyoshi Hachiya, Takeshi Iwaya, Gordon B. Mills, Masashi Fujita, Yiling Lu, Noriyuki Sasaki, Tamotsu Sugai, Satoshi Nishizuka, Ryo Sugimoto, Fumitaka Endo
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0239966 (2020)
PLoS ONE
PLoS ONE
Circulating tumor DNA (ctDNA) is released from tumor cells into blood in advanced cancer patients. Although gene mutations in individual tumors can be diverse and heterogenous, ctDNA has the potential to provide comprehensive biomarker information. H
Publikováno v:
Cancer Research. 79:1378-1378
Precise relapse prediction in cancer patients is urgently needed as conventional serum tumor markers do not predict relapse in a timely manner. Circulating tumor DNA (ctDNA) is a new class of quantitative biomarkers that reflect tumor burden. The ctD
Autor:
Ken Sakata, Chihaya Maesawa, Gen Tamura, Yuji Suzuki, Takeshi Iwaya, Teiichi Motoyama, Satoshi Nishizuka, Yasushi Endoh
Publikováno v:
European Journal of Cancer. 35:316-319
The non-coding control region of mitochondrial DNA (mtDNA), containing the hypervariable regions HV1 and HV2 and the D-loop region, was screened for mutations in 45 gastric tumours (15 tumours each of adenoma, differentiated adenocarcinoma and undiff
Autor:
Takeshi Iwaya, Gen Tamura, Kazuyoshi Saito, M Terashima, Ryoichi Satodate, Satoshi Nishizuka, Ken Sakata, Yasushi Suzuki, Chihaya Maesawa
Publikováno v:
Japanese Journal of Cancer Research : Gann
We investigated the E (epithelial)‐cadherin gene for mutations and loss of heterozygosity (LOH) in 24 primary gastric carcinomas (12 differentiated and 12 undifferentiated types, including 3 signet‐ring cell carcinomas), as well as 4 gastric carc
Autor:
Akira Sasaki, Yoshihiro Shioi, Takeshi Iwaya, Kohei Kume, Chie Ito, Fumitaka Endo, Satoshi Nishizuka, Suburu Amano, Yuji Akiyama, Koshi Mimori
Publikováno v:
Cancer Research. 76:1162-1162
[Background] Tylosis is an autosomal dominant skin disorder that is associated with the early onset of esophageal squamous cell carcinoma (ESCC) in several families. The tylosis esophageal cancer (TOC) gene locus has been mapped to chromosome 17q25.1
Autor:
Go Wakabayashi, Takeshi Iwaya, Miyuki Ikeda, Teppei Matsuo, Kazushige Ishida, Satoshi Nishizuka
Publikováno v:
BMC Research Notes, Vol 4, Iss 1, p 140 (2011)
BMC Research Notes
BMC Research Notes
Background The binding of EGFR and its ligands leads to autophosphorylation of receptor tyrosine kinase as well as subsequent activation of signal transduction pathways that are involved in regulating cellular proliferation, differentiation, and surv
Autor:
Takeshi Iwaya, Masaki Mori, Ryunosuke Kogo, Koshi Mimori, Kazuo Shirouzu, Hiromasa Fujita, Naohiro Nishida, Fumiaki Tanaka, Tomoya Sudo, Kohei Shibata
Publikováno v:
Oncology reports. 26(4)
The aim of this study was to identify and evaluate novel prognostic markers for gastric cancer. Differential mRNA displays comparing paired tumor/normal stomach samples were assessed. Several differentially expressed cDNA fragments of candidate genes
Autor:
Kazuyoshi Saito, Yasushi Suzuki, Gen Tamura, Ken Sakata, Takeshi Iwaya, Ryoichi Satodate, Satoshi Nishizuka, Chihaya Maesawa, Masanori Terashima
Publikováno v:
Japanese Journal of Cancer Research : Gann
Allelic loss on chromosome 18q is involved in the progression of gastric carcinoma. Recently, DPC4 (deleted in pancreatic carcinoma, locus 4), a candidate tumor suppressor gene, has been localized at 18q21.1. This gene is inactivated in nearly one ha