Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Stephen S Whitehead"'
Autor:
Erwin de Bruin, Tran Thi Nhu Thao, Marion Koopmans, Stephen S. Whitehead, Huynh Thi Phuong, Bridget Wills, Nguyen Thi Hanh Tien, Maciej F. Boni, Nguyen Ha Thao Vy, Hannah E. Clapham, Huynh Thi Le Duyen, Henk-Jan van den Ham
Publikováno v:
The Journal of Infectious Diseases
Journal of Infectious Diseases, 223(12), 2053-2061. Oxford University Press
Tran, Thi Nhu Thao; de Bruin, Erwin; Phuong, Huynh Thi; Thao Vy, Nguyen Ha; van den Ham, Henk-Jan; Wills, Bridget A; Tien, Nguyen Thi Hanh; Le Duyen, Huynh Thi; Trung, Dinh The; Whitehead, Stephen S; Boni, Maciej F; Koopmans, Marion; Clapham, Hannah E (2021). Using NS1 Flavivirus Protein Microarray to Infer Past Infecting Dengue Virus Serotype and Number of Past Dengue Virus Infections in Vietnamese Individuals. The journal of infectious diseases, 223(12), pp. 2053-2061. Oxford University Press 10.1093/infdis/jiaa018
Journal of Infectious Diseases, 223(12), 2053-2061. Oxford University Press
Tran, Thi Nhu Thao; de Bruin, Erwin; Phuong, Huynh Thi; Thao Vy, Nguyen Ha; van den Ham, Henk-Jan; Wills, Bridget A; Tien, Nguyen Thi Hanh; Le Duyen, Huynh Thi; Trung, Dinh The; Whitehead, Stephen S; Boni, Maciej F; Koopmans, Marion; Clapham, Hannah E (2021). Using NS1 Flavivirus Protein Microarray to Infer Past Infecting Dengue Virus Serotype and Number of Past Dengue Virus Infections in Vietnamese Individuals. The journal of infectious diseases, 223(12), pp. 2053-2061. Oxford University Press 10.1093/infdis/jiaa018
Background In recent years, researchers have had an increased focus on multiplex microarray assays, in which antibodies are measured against multiple related antigens, for use in seroepidemiological studies to infer past transmission. Methods We asse
Autor:
Leslie Goo, Pavle S. Milutinovic, Christina R. DeMaso, Kimberly A. Dowd, Theodore C. Pierson, Laura A. VanBlargan, Stephen S. Whitehead, Anna P. Durbin
Publikováno v:
J Virol
Dengue virus cocirculates globally as four serotypes (DENV1 to -4) that vary up to 40% at the amino acid level. Viral strains within a serotype further cluster into multiple genotypes. Eliciting a protective tetravalent neutralizing antibody response
Autor:
Huy A. Tu, Donna M. Rizzo, Sean A. Diehl, Nicholas Selig, Kristen K. Pierce, Stephen S. Whitehead, Roxana del Rio-Guerra, Korin Eckstrom, Anna P. Durbin, Seth Frietze, Beth D. Kirkpatrick, Dorothy M. Dickson, Julie A. Dragon, John P. Hanley, Samuel V. Scarpino, Scott Tighe
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
About 20–25% of dengue virus (DENV) infections become symptomatic ranging from self-limiting fever to shock. Immune gene expression changes during progression to severe dengue have been documented in hospitalized patients; however, baseline or kine
Autor:
Jesica Swanstrom, Daniel Emerling, Kristen K. Pierce, Usha K. Nivarthi, Sean A. Diehl, Beth D. Kirkpatrick, Aravinda M. de Silva, Stephen S. Whitehead, Anna P. Durbin, Huy A. Tu, Ralph S. Baric, Ngan Nguyen, Bhumi Patel, Matthew J. Delacruz
Publikováno v:
EBioMedicine. 41:465-478
Background Acute viral infections induce a rapid and transient increase in antibody-secreting plasmablasts. At convalescence, memory B cells (MBC) and long-lived plasma cells (LLPC) are responsible for long-term humoral immunity. Following an acute v
Autor:
Bhumi Patel, Stephen S. Whitehead, Boyd Yount, Anna P. Durbin, Douglas G. Widman, Aravinda M. de Silva, Usha K. Nivarthi, Jesica Swanstrom, Ralph S. Baric, Matthew J. Delacruz
Publikováno v:
The Journal of Infectious Diseases
National Institutes of Health monovalent dengue vaccines and natural primary dengue virus infections elicit serotype-specific neutralizing antibodies that recognize similar epitopes.
Background Dengue virus is an emerging mosquito-borne flavivir
Background Dengue virus is an emerging mosquito-borne flavivir
Autor:
Nancy R. Graham, Stephen S. Whitehead, Anna P. Durbin, Usha K. Nivarthi, Jonathan E. Boyson, Huy A. Tu, Kristen K. Pierce, Matthew J. Delacruz, Philip Eisenhauer, Jason Botten, Aravinda Desilva, Beth D. Kirkpatrick, Sean A. Diehl
Publikováno v:
Cell Reports Medicine
Summary The tetravalent live attenuated dengue vaccine candidate TV003 induces neutralizing antibodies against all four dengue virus serotypes (DENV1–DENV4) and protects against experimental challenge with DENV2 in humans. Here, we track vaccine vi
Autor:
Jennifer E. Munt, Aravinda M. de Silva, Stephen S. Whitehead, Anna P. Durbin, Ralph S. Baric, Usha K. Nivarthi, Matthew J. Delacruz, David R. Martinez, Boyd Yount
Publikováno v:
Cell Reports, Vol 33, Iss 1, Pp 108226-(2020)
Cell reports
Cell reports
SUMMARY Dengue virus (DENV) infects an estimated 390 million people each year worldwide. As tetravalent DENV vaccines have variable efficacy against DENV serotype 2 (DENV2), we evaluated the role of genetic diversity within the pre-membrane (prM) and
Autor:
Beth D. Kirkpatrick, Melissa Cook, Michele Sausser, Beulah P. Sabundayo, Liman Wang, Stephen S. Whitehead, Helen He, Anna P. Durbin, Donna Hyatt, Kristen K. Pierce, Jeffrey R. Sachs, Beth Ann Coller, Amy Falk Russell, Andrew W. Lee, Jason C. Martin, Palmtama L. Grier
Publikováno v:
Am J Trop Med Hyg
New dengue vaccines are needed to prevent this globally expanding vector-borne disease. The V180 vaccine candidate consists of four recombinant, soluble, dengue virus envelope glycoproteins and has been previously evaluated in two clinical trials for
Autor:
Aruna D. De Silva, Alba Grifoni, Angel Balmaseda, Conner K. Kidd, James D. Brien, Stephen S. Whitehead, Hannah Voic, Anna P. Durbin, Alessandro Sette, Eva Harris, Daniela Weiskopf, Sandeep Kumar Dhanda, Anette Stryhn, Søren Buus, Sean A. Diehl
Publikováno v:
J Virol
Members of the flavivirus genus share a high level of sequence similarity and often circulate in the same geographical regions. However, whether T cells induced by one viral species cross-react with other related flaviviruses has not been globally ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d53f89312b3917146627da30d715e0
Autor:
Stephen S. Whitehead, Kristen K. Pierce, Anna P. Durbin, Aravinda Desilva, Jonathan E. Boyson, Beth D. Kirkpatrick, Jason Botten, Sean A. Diehl, Usha K. Nivarthi, Huy A. Tu, Matthew J. Delacruz
Publikováno v:
SSRN Electronic Journal.
The tetravalent live attenuated dengue vaccine candidate TV003 induces neutralizing antibodies against all four dengue virus serotypes (DENV1-4), and protects against experimental DENV2 challenge in humans. Protection occurred with or without a secon