Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Robert A. Anders"'
Autor:
June L. Chan, Christine M. Dejea, Shruthi Sriramkumar, Sepideh Besharati, John H. Michel, Hongni Fan, Hao Wang, Alyssa Wenzel, Franck Housseau, Robert A. Anders, Liam Chung, Jessica L. Hicks, Angelo M. De Marzo, Ram Podicheti, Ada J. Tam, Ashley R. Maiuri, James R. White, Stephen B. Baylin, Christina E. DeStefano Shields, Douglas B. Rusch, Heather M. O'Hagan, Cynthia L. Sears
Publikováno v:
Cancer Discovery. 11:1792-1807
Colorectal cancer is multifaceted, with subtypes defined by genetic, histologic, and immunologic features that are potentially influenced by inflammation, mutagens, and/or microbiota. Colorectal cancers with activating mutations in BRAF are associate
Autor:
Teniola Oke, Thomas B. Schaffer, Evan J. Lipson, Dung T. Le, Christian F. Meyer, Lingling Chen, John Mc Mahon Gross, Laurene S. Cheung, Jillian T. Ngo, Nicolas J. Llosa, Janis M. Taube, Holly Kemberling, Karim Boudadi, John-William Sidhom, Robert A. Anders, Drew M. Pardoll, Luis A. Diaz
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Undifferentiated pleomorphic sarcoma (UPS), an aggressive soft-tissue sarcoma of adults, has been characterized by low tumor mutational burden (TMB) and high copy number alterations. Clinical trials of programmed death-1 (PD-1) blockade in UPS have r
Publikováno v:
Biochem Biophys Res Commun
PTEN and p53 are highly mutated in many cancers. These two tumor suppressors have critical functions in the nucleus, such as DNA repair, cell cycle progression, and genome maintenance. However, the in vivo functional relationship of nuclear PTEN and
Publikováno v:
American Journal of Infection Control
Highlights •COVID-19 in health care workers (HCWs) cause relatively few deaths.•Personal Protective Equipment (PPE) including coveralls and designated COVID-19 hospitals help reduce the infections in HCWs.•Using WHO guidelines for Ebola China c
Autor:
Aleksandra Popovic, Nina Chu, Minwei Cao, Alexander Hopkins, Elana J. Fertig, Todd D. Armstrong, Robert A. Anders, Bridget P. Keenan, Jacquelyn W. Zimmerman, Elizabeth M. Jaffee
Publikováno v:
Cancer Prev Res (Phila)
Almost all pancreatic ductal adenocarcinomas (PDA) develop following KRAS activation, which triggers epithelial transformation and recruitment of desmoplastic stroma through additional transcriptional and epigenetic regulation, but only a few of thes
Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria
Autor:
John M. Craig, Shaoguang Wu, Christina E. DeStefano Shields, Xinqun Wu, Robert A. Anders, Christine M. Dejea, Rahwa Taddese, Hao Wang, Abby L. Geis, David L. Huso, Drew M. Pardoll, Francis M. Giardiello, Elizabeth C. Wick, Annemarie Boleij, Franck Housseau, Payam Fathi, Elizabeth M. Hechenbleikner, Cynthia L. Sears
Publikováno v:
Science, 359, 6375, pp. 592-597
Science, 359, 592-597
Science, 359, 592-597
Biofilms provide refuge for cancerous bacteria Familial adenomatous polyposis (FAP) causes benign polyps along the colon. If left untreated, FAP leads to a high incidence of colon cancer. To understand how polyps influence tumor formation, Dejea et a
Autor:
Tatsuya Yamada, Takashi Kato, Robert A. Anders, Hideki Nakamura, Miho Iijima, Hiromi Sesaki, Atsushi Igarashi
Publikováno v:
iScience
iScience, Vol 23, Iss 10, Pp 101548-(2020)
iScience, Vol 23, Iss 10, Pp 101548-(2020)
Summary The PTEN gene is highly mutated in many cancers, including hepatocellular carcinoma. The PTEN protein is located at different subcellular regions—PTEN at the plasma membrane suppresses PI3-kinase signaling in cell growth, whereas PTEN in th
Publikováno v:
Digestive and Liver Disease. 47(10):826-835
The liver is a vital organ that plays a major role in many bodily functions from protein production and blood clotting to cholesterol, glucose and iron metabolism and nutrition storage. Maintenance of liver homeostasis is critical for these essential
Publikováno v:
Journal of Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is the sixth most common cancer and the third most common cause of cancer-related mortality worldwide. Due to the poor prognosis and limited therapeutic options, there is great interest in further understanding better t
Autor:
Alan E. Berger, Alan K. Meeker, Tracee L. McMiller, Robert A. Anders, Shuming Chen, Aleksandra Ogurtsova, Suzanne L. Topalian, Maria Libera Ascierto, Richard F. Ambinder, Janis M. Taube, Neil A. Phillips, Amy S. Duffield, Haiying Xu, Drew M. Pardoll
Classical Hodgkin lymphoma (CHL) is a neoplasm characterized by robust inflammatory infiltrates and heightened expression of the immunosuppressive PD-1/PD-L1 pathway. Although anti-PD-1 therapy can be effective in >60% of patients with refractory CHL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4ffb0cd6533b6dcecd996dedf09c47
https://europepmc.org/articles/PMC5727974/
https://europepmc.org/articles/PMC5727974/