Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Federico M. Giorgi"'
Autor:
Pierangelo Veltri, Daniele Mercatelli, Elisabetta Pedace, Pietro Hiram Guzzi, Federico M. Giorgi
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 4092-4100 (2021)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Graphical abstract
Motivation: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (coronavirus disease, 2019; COVID-19) is associated with adverse outcomes in patients. It has been observed that lethality seems to be related
Motivation: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (coronavirus disease, 2019; COVID-19) is associated with adverse outcomes in patients. It has been observed that lethality seems to be related
MotivationSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (coronavirus disease, 2019; COVID-19) is associated with adverse outcomes in patients. It has been observed that lethality seems to be related to the age of patients. Mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fd036af31642e5a082d48ea5a4a5c05
https://doi.org/10.1101/2021.05.23.21257669
https://doi.org/10.1101/2021.05.23.21257669
Publikováno v:
Journal of Biomolecular Structure and Dynamics
Journal of Biomolecular Structure & Dynamics
article-version (VoR) Version of Record
Journal of Biomolecular Structure & Dynamics
article-version (VoR) Version of Record
SARS-CoV-2 entry in human cells is mediated by the interaction between the viral Spike protein and the human ACE2 receptor. This mechanism evolved from the ancestor bat coronavirus and is currently one of the main targets for antiviral strategies. Ho
Autor:
Barry Honig, Diana Murray, Alexander Lachmann, Peter K. Jackson, David R. Simpson, Andrea Califano, E. Alejandro Sweet-Cordero, Sunny J. Jones, Somnath Tagore, Brennan Chu, Evan O. Paull, Federico M. Giorgi, Joshua Broyde, Aaron T. Griffin
Publikováno v:
Nature biotechnology, vol 39, iss 2
Nat Biotechnol
Nat Biotechnol
Tumor-specific elucidation of physical and functional oncoprotein interactions could improve tumorigenic mechanism characterization and therapeutic response prediction. Current interaction models and pathways, however, lack context specificity and ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d750cb705059dd4f64232fd4130928bd
http://hdl.handle.net/11585/785854
http://hdl.handle.net/11585/785854
Autor:
Daniele Mercatelli, Federico M. Giorgi
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 11 (2020)
Frontiers in Microbiology, Vol 11 (2020)
The novel respiratory disease COVID-19 has reached the status of worldwide pandemic and large efforts are currently being undertaken in molecularly characterizing the virus causing it, SARS-CoV-2. The genomic variability of SARS-CoV-2 specimens scatt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f83cefe826718ecc0b4ffef83e391a9
Publikováno v:
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 9, Iss 982, p 982 (2020)
Journal of Clinical Medicine, 9(4):982
Volume 9
Issue 4
Journal of Clinical Medicine, Vol 9, Iss 982, p 982 (2020)
Journal of Clinical Medicine, 9(4):982
Volume 9
Issue 4
the recent epidemic outbreak of a novel human coronavirus called SARS-CoV-2 and causing the respiratory tract disease COVID-19 has reached worldwide resonance and a global effort is being undertaken to characterize the molecular features and evolutio
Autor:
Carmine Ceraolo, Federico M. Giorgi
Publikováno v:
Journal of Medical Virology
There is a rising global concern for the recently emerged novel coronavirus (2019‐nCoV). Full genomic sequences have been released by the worldwide scientific community in the last few weeks to understand the evolutionary origin and molecular chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298b8e840f543b4dc311fb187e2517d7
http://hdl.handle.net/11585/753851
http://hdl.handle.net/11585/753851
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 10 (2019)
Frontiers in Genetics, Vol 10 (2019)
Cancer is a disease often characterized by the presence of multiple genomic alterations, which trigger altered transcriptional patterns and gene expression, which in turn sustain the processes of tumorigenesis, tumor progression, and tumor maintenanc
Cancer is a disease often characterized by the presence of multiple genomic alterations, which trigger altered transcriptional patterns and gene expression, which in turn sustain the processes of tumorigenesis, tumor progression and tumor maintenance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53dc38669bc6e3e753f49a6f0d4b3a76
Autor:
Andrea Califano, Federico M. Giorgi, E. Alejandro Sweet-Cordero, Barry Honig, Diana Murray, Peter K. Jackson, David R. Simpson, Alexander Lachmann, Joshua Broyde
The largely incomplete and tissue-independent nature of cancer pathways represents a key limitation to the ability to elucidate mechanistic determinants of cancer phenotypes and to predict adaptive response to targeted therapy. To address these chall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe04232ca62dc4f17af0362a313792cc
https://doi.org/10.1101/289538
https://doi.org/10.1101/289538