Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Carl W. White"'
Autor:
Isabella Annesi-Maesano, Urmila P. Kodavanti, Frank D. Gilliland, Esteban G. Burchard, Christopher Carlsten, Haneen Khreis, Carl W. White, Rob McConnell, George D. Thurston, Steven R. Kleeberger, Erika Garcia, Joan Reibman, Laura S. Van Winkle, John R. Balmes, Jack R. Harkema, Kent E. Pinkerton, Mary B. Rice, Dave B Peden, Tamara Schikowski, Stephanie J. London
Publikováno v:
Annals of the American Thoracic Society
Annals of the American Thoracic Society, vol 17, iss 4
Annals of the American Thoracic Society, vol 17, iss 4
Although it is well accepted that air pollution exposure exacerbates preexisting airway disease, it has not been firmly established that long-term pollution exposure increases the risk of new-onset asthma or chronic obstruction pulmonary disease (COP
Autor:
Ruth M. Seeber, Carl W. White, Audrey S. M. Chan, Heng B. See, Rekhati S. Abhayawardana, Ivan Ivanovich Dedov, Anatoly Tiulpakov, Kevin D. G. Pfleger, Julian Ik-Tsen Heng, Nathan J. Pavlos
Publikováno v:
Molecular Endocrinology
Nephrogenic syndrome of inappropriate antidiuresis (NSIAD) is a genetic disease first described in 2 unrelated male infants with severe symptomatic hyponatremia. Despite undetectable arginine vasopressin levels, patients have inappropriately concentr
Autor:
Swetha Inturi, Rama Kant, Carl W. White, Dileep Kumar, Anil K. Jain, Neera Tewari-Singh, Rajesh Agarwal, Chapla Agarwal
Publikováno v:
Toxicology Letters. 235:161-171
Our recent studies in SKH-1 hairless mice have demonstrated that topical exposure to nitrogen mustard (NM), an analog of sulfur mustard (SM), triggers the inflammatory response, microvesication and apoptotic cell death. Here, we sought to identify th
Autor:
Chapla Agarwal, Carl W. White, Dileep Kumar, Rajesh Agarwal, Neera Tewari-Singh, Swetha Inturi, David J. Orlicky, Anil K. Jain
Publikováno v:
Toxicology and Applied Pharmacology. 285:71-78
Currently, there is no effective antidote to prevent skin injuries by sulfur mustard (SM) and nitrogen mustard (NM), which are vesicating agents with potential relevance to chemical warfare, terrorist attacks, or industrial/laboratory accidents. Our
Autor:
Chapla Agarwal, Carl W. White, Rajesh Agarwal, Neera Tewari-Singh, David J. Orlicky, Anil K. Jain, Brian J. Day, Swetha Inturi
Publikováno v:
Free Radical Biology and Medicine. 72:285-295
Our previous studies and other published reports on the chemical warfare agent sulfur mustard (SM) and its analog 2-chloroethyl ethyl sulfide (CEES) have indicated a role of oxidative stress in skin injuries caused by these vesicating agents. We exam
Autor:
Joan E. Loader, Cameron S. McElroy, Jackie S. Rioux, Brian J. Day, Rhonda B. Garlick, Tara B. Hendry-Hofer, Dana R. Anderson, Elysia Min, Chris Osborne, Carl W. White, Danielle C. Paradiso, Livia A. Veress, Wesley W. Holmes, Jie Huang, Russell W. Smith
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 154(2)
Sulfur mustard (bis 2-chloroethyl ethyl sulfide, SM) is a powerful bi-functional vesicating chemical warfare agent. SM tissue injury is partially mediated by the overproduction of reactive oxygen species resulting in oxidative stress. We hypothesized
Autor:
Joan E. Loader, Tara B. Hendry-Hofer, Brian J. Day, Heidi C. O'Neill, David J. Orlicky, Carl W. White
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 45:323-331
The inhalation of sulfur mustard (SM) causes substantial deposition in the nasal region. However, specific injury has not been characterized. 2-chloroethyl ethyl sulfide (CEES) is an SM analogue used to model injury and screen potential therapeutics.
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 336:450-459
Exposure to chemical warfare agent sulfur mustard (HD) is reported to cause GSH depletion, which plays an important role in HD-linked oxidative stress and skin injury. Using the HD analog 2-chloroethyl ethyl sulfide (CEES), we evaluated the role of G
Autor:
Brian J. Day, Elysia Min, Heidi C. O'Neill, Raymond C. Rancourt, Livia A. Veress, Tara B. Hendry-Hofer, Jie Huang, Joan E. Loader, Carl W. White
Publikováno v:
Free Radical Biology and Medicine. 48:1188-1196
Sulfur mustard (bis-2-(chloroethyl) sulfide, SM) is a highly reactive vesicating and alkylating chemical warfare agent. A SM analog, 2-chloroethyl ethyl sulfide (CEES) has been utilized to elucidate mechanisms of toxicity and as a screen for therapeu
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 328:732-739
Sulfur mustards (SMs) have been used as warfare agents since World War I and still pose a significant threat against civilian and military personnel. SM exposure can cause significant blistering of the skin, respiratory injury, and fibrosis. No antid