Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Alexandra F. Santos"'
Publikováno v:
Santos, A F, Alpan, O & Hoffmann, H-J 2021, ' Basophil activation test : Mechanisms and considerations for use in clinical trials and clinical practice ', Allergy: European Journal of Allergy and Clinical Immunology, vol. 76, no. 8, pp. 2420-2432 . https://doi.org/10.1111/all.14747
The basophil activation test (BAT) is a functional assay that measures the degree of degranulation following stimulation with allergen or controls by flow cytometry. It correlates directly with histamine release. From the dose-response curve resultin
Publikováno v:
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and ImmunologyREFERENCES. 32(7)
BACKGROUND Immediate food-allergic reactions are IgE-mediated, but many individuals with detectable allergen-specific IgE do not react to the food. Allergen-specific IgG may interfere with allergen-IgE interaction and/or through intracellular inhibit
Publikováno v:
Current Pediatric Reviews. 14:139-149
An accurate diagnosis of food allergy is extremely important to guide safe and yet not overly restrictive dietary management. The cornerstone of the diagnosis of food allergy is the clinical history; it allows appropriate selection of the allergens t
Groundbreaking Discoveries in ImmunologyTitle : IgE sialylation: unravelling a key anaphylactic mediatorAuthors : Beatriz Moyaa, Chiara Tontinib and Alexandra Santosc, d, e, fa. Allergy Service. Hospital Universitario 12 de Octubre, Madrid, Spainb. L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c3e0969e449306c4a6d0a2f59c743b2
https://doi.org/10.22541/au.160349179.91699903/v1
https://doi.org/10.22541/au.160349179.91699903/v1
Publikováno v:
Hemmings, O, Du Toit, G, Radulovic, S, Lack, G & Santos, A F 2020, ' Ara h 2 is the dominant peanut allergen despite similarities with Ara h 6 ', Journal of Allergy and Clinical Immunology, vol. 146, no. 3, pp. 621-630.e5 . https://doi.org/10.1016/j.jaci.2020.03.026
The Journal of Allergy and Clinical Immunology
The Journal of Allergy and Clinical Immunology
Background Arachis hypogaea 2 (Ara h 2)-specific IgE is to date the best serologic marker to diagnose peanut allergy. Ara h 6 shares approximately 60% sequence identity and multiple epitopes with Ara h 2. Objective Our aim was to assess the diagnosti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed960d33a8555e1589692b3747c0946
https://kclpure.kcl.ac.uk/en/publications/15b65006-8bc6-48be-990f-09cfd013f093
https://kclpure.kcl.ac.uk/en/publications/15b65006-8bc6-48be-990f-09cfd013f093
Autor:
Gideon Lack, Natalia Bécares, Ekaterina Khaleva, George Du Toit, Kristina M. Harris, Natália Couto-Francisco, Graham Roberts, Colin O’Rourke, Suzana Radulovic, Peter H. Sayre, Marshall Plaut, David W. Larson, Henry T. Bahnson, Monica Basting, Alexandra F. Santos
Publikováno v:
Santos, A F, Du Toit, G, O'Rourke, C, Becares, N, Couto-Francisco, N, Radulovic, S, Khaleva, E, Basting, M, Harris, K M, Larson, D, Sayre, P, Plaut, M, Roberts, G, Bahnson, H T & Lack, G 2020, ' Biomarkers of severity and threshold of allergic reactions during oral peanut challenges ', Journal of Allergy and Clinical Immunology, vol. 146, no. 2, pp. 344-355 . https://doi.org/10.1016/j.jaci.2020.03.035
The Journal of Allergy and Clinical Immunology
The Journal of Allergy and Clinical Immunology
Background Oral food challenge (OFC) is the criterion standard to assess peanut allergy (PA), but it involves a risk of allergic reactions of unpredictable severity. Objective Our aim was to identify biomarkers for risk of severe reactions or low dos
Autor:
Ulugbek Nurmatov, Aziz Sheikh, Kari C. Nadeau, Edward F. Knol, Mika J. Mäkelä, Carsten Bindslev-Jensen, R. G. Van Wijk, Ioana Agache, M. Ebisawa, Oliver Pfaar, E-M. Varga, S. Dhami, Cezmi A. Akdis, Philippe Eigenmann, Y Boloh, Cansin Sackesen, Nikolaos G. Papadopoulos, Montserrat Alvaro-Lozano, G. Du Toit, Graham Roberts, Antonella Muraro, Montserrat Fernandez-Rivas, Elizabeth Angier, Kirsten Beyer, Stefania Arasi, Dermot Ryan, Steffen Lau, Marek Jutel, Liam O'Mahony, R. van Ree, Susanne Halken, Gunter J. Sturm, Alexandra F. Santos, Giovanni B. Pajno, Lars K. Poulsen, Wesley Burks
Publikováno v:
Allergy, 73(4), 799-815. Wiley-Blackwell
ALLERGY
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
Pajno, G B, Fernandez-Rivas, M, Arasi, S, Roberts, G, Akdis, C A, Alvaro-Lozano, M, Beyer, K, Bindslev-Jensen, C, Burks, W, Ebisawa, M, Eigenmann, P, Knol, E, Nadeau, K C, Poulsen, L K, van Ree, R, Santos, A F, du Toit, G, Dhami, S, Nurmatov, U, Boloh, Y, Makela, M, O'Mahony, L, Papadopoulos, N, Sackesen, C, Agache, I, Angier, E, Halken, S, Jutel, M, Lau, S, Pfaar, O, Ryan, D, Sturm, G, Varga, E-M, van Wijk, R G, Sheikh, A, Muraro, A & EAACI Allergen Immunotherapy Guidelines Group 2018, ' EAACI Guidelines on allergen immunotherapy : IgE-mediated food allergy ', Allergy: European Journal of Allergy and Clinical Immunology, vol. 73, no. 4, pp. 799-815 . https://doi.org/10.1111/all.13319
Allergy, 73(4), 799-815. Wiley-Blackwell Publishing Ltd
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
Allergy, Vol. 73, No 4 (2018) pp. 799-815
ALLERGY
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
Pajno, G B, Fernandez-Rivas, M, Arasi, S, Roberts, G, Akdis, C A, Alvaro-Lozano, M, Beyer, K, Bindslev-Jensen, C, Burks, W, Ebisawa, M, Eigenmann, P, Knol, E, Nadeau, K C, Poulsen, L K, van Ree, R, Santos, A F, du Toit, G, Dhami, S, Nurmatov, U, Boloh, Y, Makela, M, O'Mahony, L, Papadopoulos, N, Sackesen, C, Agache, I, Angier, E, Halken, S, Jutel, M, Lau, S, Pfaar, O, Ryan, D, Sturm, G, Varga, E-M, van Wijk, R G, Sheikh, A, Muraro, A & EAACI Allergen Immunotherapy Guidelines Group 2018, ' EAACI Guidelines on allergen immunotherapy : IgE-mediated food allergy ', Allergy: European Journal of Allergy and Clinical Immunology, vol. 73, no. 4, pp. 799-815 . https://doi.org/10.1111/all.13319
Allergy, 73(4), 799-815. Wiley-Blackwell Publishing Ltd
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
Allergy, Vol. 73, No 4 (2018) pp. 799-815
Food allergy can result in considerable morbidity, impairment of quality of life, and healthcare expenditure. There is therefore interest in novel strategies for its treatment, particularly food allergen immunotherapy (FA-AIT) through the oral (OIT),
Publikováno v:
Current Allergy and Asthma Reports
Purpose of Review The basophil activation test (BAT) using flow cytometry has supplanted traditional methods of measuring basophil degranulation using histamine and other mediator release, and can be used for clinical applications as well as to explo
Publikováno v:
The Journal of Allergy and Clinical Immunology
Background IgE mediates allergic reactions to peanut; however, peanut-specific IgE (sIgE) levels do not always equate to clinical peanut allergy. Qualitative differences between sIgE of peanut-sensitized but tolerant (PS) and peanut-allergic (PA) ind
Autor:
Oliver Hausmann, Paul Rouzaire, Tatjana Pecaric-Petkovic, Wayne G. Shreffler, Sarita U. Patil, Marta Ferrer, Hans Jürgen Hoffmann, Didier G. Ebo, Cristobalina Mayorga, Bernadette Eberlein, Anna Nopp, Edward F. Knol, Peter Korošec, Vito Sabato, Alexandra F. Santos, Maria L. Sanz
Publikováno v:
ALLERGO JOURNAL
Allergo Journal, 25(4), 26. Urban & Vogel GmbH
Eberlein, B, Santos, A F, Mayorga, C, Nopp, A, Ferrer, M, Rouzaire, P, Ebo, D, Sabato, V, Sanz, M L, Pecaric-Petkovic, T, Patil, S U, Hausmann, O V, Shreffler, W G, Korosec, P, Knol, E F & Hoffmann, H J 2016, ' Basophil activation testing in diagnosis and monitoring of allergic disease-An overview ', Allergo Journal, vol. 25, no. 4, pp. 26-33 . https://doi.org/10.1007/s15007-016-1105-y
Eberlein, B, Santos, A F, Mayorga, C, Nopp, A, Ferrer, M, Rouzaire, P, Ebo, D, Sabato, V, Sanz, M L, Pecaric-Petkovic, T, Patil, S U, Hausmann, O V, Shreffler, W G, Korosec, P, Knol, E F & Hoffmann, H J 2016, ' Basophil activation testing in diagnosis and monitoring of allergic disease-An overview ', Allergo Journal, vol. 25, no. 4, pp. 26-33 . https://doi.org/10.1007/s40629-016-0116-2
Allergo Journal, 25(4), 26. Urban & Vogel GmbH
Eberlein, B, Santos, A F, Mayorga, C, Nopp, A, Ferrer, M, Rouzaire, P, Ebo, D, Sabato, V, Sanz, M L, Pecaric-Petkovic, T, Patil, S U, Hausmann, O V, Shreffler, W G, Korosec, P, Knol, E F & Hoffmann, H J 2016, ' Basophil activation testing in diagnosis and monitoring of allergic disease-An overview ', Allergo Journal, vol. 25, no. 4, pp. 26-33 . https://doi.org/10.1007/s15007-016-1105-y
Eberlein, B, Santos, A F, Mayorga, C, Nopp, A, Ferrer, M, Rouzaire, P, Ebo, D, Sabato, V, Sanz, M L, Pecaric-Petkovic, T, Patil, S U, Hausmann, O V, Shreffler, W G, Korosec, P, Knol, E F & Hoffmann, H J 2016, ' Basophil activation testing in diagnosis and monitoring of allergic disease-An overview ', Allergo Journal, vol. 25, no. 4, pp. 26-33 . https://doi.org/10.1007/s40629-016-0116-2
The nature of basophil activation as an ex vivo challenge makes it a multifaceted and promising tool for the allergist. Through the development of flow cytometry, discovery of activation markers such as CD63 and markers identifying basophil granulocy