Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Wenyu Lin"'
Autor:
Yongfu Huang, Esperance A. Schaefer, Yongju Zhao, Ming-Lung Yu, Haoju Wang, Zeng Tu, Chuanlong Zhu, Anna Lidofsky, Xiaoqiong Duan, Zhiwen Xu, Raymond T. Chung, Dachuan Cai, Shadi Salloum, Shilin Li, Limin Chen, Jian Hong, Wenyu Lin, Jacinta A. Holmes, Wenting Li, Sae Hwan Lee, Xiao Liu
Publikováno v:
Hepatology. 69:1004-1019
Long noncoding RNAs (lncRNAs) play a critical role in the regulation of many important cellular processes. However, the mechanisms by which lncRNAs regulate viral infection and host immune responses are not well understood. We sought to explore lncRN
Autor:
Hong Zhao, Leiliang Zhang, Guoyang Wu, Shaoyong Li, Kattareeya Kumthip, Ethan M. Weinberg, Wen-Chi Chen, Mark A. Brockman, Wenyu Lin, Nikolaus Jilg, Lee F. Peng, Jorge Méndez-Navarro, Detlef Schuppan, Kaku Goto, Raymond T. Chung
Publikováno v:
The Journal of Biological Chemistry
HIV/HCV coinfection leads to accelerated hepatic fibrosis progression, with higher rates of cirrhosis, liver failure, and liver death than does HCV mono-infection. However, the profibrogenic role of HIV on hepatocytes and hepatic stellate cells (HSC)
Autor:
Yoichi Hiasa, Raymond T. Chung, Wenyu Lin, Emmett V. Schmidt, Won Hyeok Choe, Yoshitaka Kamegaya, Jason T. Blackard
Publikováno v:
Gastroenterology. 128:1034-1041
Background & Aims: The molecular mechanisms by which hepatitis C virus (HCV) antagonizes the antiviral actions of interferon (IFN) have not been fully characterized. Specifically, how HCV proteins impact on IFN signaling components has yet to be eluc
Autor:
Wenyu Lin, Won Hyeok Choe, Raymond T. Chung, Jason T. Blackard, Lawrence R. Zukerberg, Yoichi Hiasa, Yoshitaka Kamegaya, Nina Fowler, Emmett V. Schmidt
Publikováno v:
Hepatology (Baltimore, Md.). 41(3)
We developed hepatitis C virus (HCV) core-E1-E2 and HCV core transgenic mice on a common genetic background to assess the contribution of HCV structural proteins to hepatocarcinogenesis. Eight-week-old core-E1-E2, core, and nontransgenic mice inbred
Autor:
Raymond T. Chung, Jae Young Jang, Leiliang Zhang, Woo Jin Chung, Lee F. Peng, Wei-Lun Tsai, Lydia L. Barlow, Guoyang Wu, Wenyu Lin, Run-Xuan Shao, Hong Zhao
Publikováno v:
Gastroenterology. 138:2509-2518.e1
Background & Aims The generation of oxidative stress and transforming growth factor β1 (TGF-β1) production play important roles in liver fibrogenesis. We have previously shown that hepatitis C virus (HCV) increases hepatocyte TGF-β1 expression. Ho