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Autor:
Ni-Chung Lee, Yin-Hsiu Chien, Yao-Hsu Yang, Ting-Wei Lin, Hsin-Hui Yu, Bor-Luen Chiang, Ya-Chiao Hu, Li-Chieh Wang
Publikováno v:
Journal of Microbiology, Immunology and Infection. 55:545-548
We reported a patient with autoimmunity (multiple sclerosis), immunodeficiency (hypogammaglobulinemia with severe infections), enteropathy (diarrhea with intestinal inflammation), splenomegaly, lymphadenopathy and lymphocytic infiltration of non-lymp
Publikováno v:
Epileptic Disorders. 24:343-352
OBJECTIVE Developmental and epileptic encephalopathy (DEE) is characterized by refractory seizures, developmental delay or intellectual disability, which may be caused by gene mutation. In this study, we explored the clinical phenotype and long-term
Autor:
George Vasmatzis, Jun Yin, Tobias Peikert, Janet Schaefer-Klein, Maria J. Disselhorst, Mitesh J. Borad, Paul Baas, Giannoula Karagouga, Stephen J. Murphy, James B. Smadbeck, Sarah H. Johnson, Julia B. Udell, Aakash Desai, John C. Cheville, Farhad Kosari, Alexa McCune, Aaron S. Mansfield
Publikováno v:
J Thorac Oncol
Journal of Thoracic Oncology, 17(3), 446-454. ELSEVIER SCIENCE INC
Journal of Thoracic Oncology, 17(3), 446-454. ELSEVIER SCIENCE INC
Introduction: The favorable outcomes with immunotherapy for mesothelioma were somewhat unexpected because this tumor has a low tumor mutation burden which has been associated with benefit in other cancers. Because chromosomal rearrangements are commo
Autor:
François Pinquie, Alain Morel, Benjamin Morvan, Jérémy Sandrini, Olivier Molinier, Alexis B. Cortot, Camille Guguen, Louise-Marie Chevalier
Publikováno v:
Clinical Lung Cancer. 23:e131-e134
Clinical Practice Points • What is already known about this subject? • Resistance mechanisms to osimertinib in T790M positive NSCLC patients are multiple and heterogeneous, combining de novo EGFR alterations (C797S mutation), EGFR-independent mec
Publikováno v:
Plant Disease. 106:634-640
Fusarium fujikuroi is the pathogen of rice bakanae disease and is subclassified into gibberellin and fumonisin groups (G and F groups). Thiophanate-methyl (TM), a benzimidazole fungicide, has been used extensively to control F. fujikuroi. Previous in
Publikováno v:
Neurobiology of Aging. 110:77-87
Advanced age is the main risk factor for the manifestation of late onset neurodegenerative diseases. Metformin, an anti-diabetic drug, was shown to extend longevity and to ameliorate the activity of recognized aging hallmarks. Here, we compared the c
Autor:
Briony L. Gliddon, Craig T. Wallington-Beddoe, Manjun Li, Darren J. Creek, Melissa R. Pitman, Melinda N. Tea, Paul Wang, Dovile Anderson, John Toubia, Melissa K. Bennett, Robert Z. Orlowski, Stuart M. Pitson, Jason A. Powell
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 24, Iss 1, Pp 1-11 (2022)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
Refereed/Peer-reviewed The introduction of the proteasome inhibitor bortezomib into treatment regimens for myeloma has led to substantial improvement in patient survival. However, whilst bortezomib elicits initial responses in many myeloma patients,
Autor:
Scott A. Beatson, Emma Ballard, David M. Whiley, Bryan A. Wee, Laura J. Sherrard, Hanna E. Sidjabat, Keyur A. Dave, Kay A. Ramsay, Keith Grimwood, Scott C. Bell, C. Duplancic, Claire E. Wainwright, Timothy J. Kidd
Publikováno v:
Journal of Cystic Fibrosis. 21:e35-e43
Background: Antimicrobial resistance in cystic fibrosis (CF) Pseudomonas aeruginosa airway infection is complex and often attributed to chromosomal mutations. How these mutations emerge in specific strains or whether particular gene mutations are cli
Publikováno v:
Canadian Journal of Microbiology. 68:31-43
Hyaluronic acid is a high-molecular-weight polysaccharide that is widely distributed in animal tissues. Bacterial hyaluronidases degrade hyaluronic acid as secreted enzymes and have been shown to contribute to infection. Staphylococcus aureus UAMS-1
Autor:
Hong-Ha M. Truong, Melissa R. Krone, Peter W. Hunt, Jeffrey N. Martin, Robin Fatch, Paula J. Lum, Steven G. Deeks
Publikováno v:
Current HIV Research. 19:497-503
Background: Antiretroviral therapy (ART) non-adherence and methamphetamine use are associated with higher HIV drug resistance prevalence. How they affect drug resistance mutations accumulation is less studied. Objective: We assessed factors associate