Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yanhui Jia"'
Autor:
Xiang He, Huayu Zhu, Yunchuan Wang, Wenbin Jia, Jing Wang, Dan Xiao, Yanhui Jia, Linlin Su, Weixia Cai, Kuo Shen, Yan Li, Dahai Hu, Yue Zhang, Ming Zhao, Jian Zhang, Kejia Wang, Li Jie, Li Zichao
Publikováno v:
Burns & Trauma
Background MicroRNA-101 (miR-101) is a tumor suppressor microRNA (miRNA) and its loss is associated with the occurrence and progression of various diseases. However, the biological function and target of miR-101 in the pathogenesis of hypertrophic sc
Autor:
Hongtao Wang, Kuo Shen, Jian Zhang, Kaituo Liu, Dahai Hu, Yunchuan Wang, Jihong Shi, Yan Li, Xujie Wang, Wei Zhang, Zhao Zheng, Jiaqi Liu, Ting He, Yanhui Jia
Publikováno v:
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-16 (2021)
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-16 (2021)
Background Hypertrophic scar (HS) is a fibro-proliferative disorder of dermis after burn or trauma and usually leads to esthetic disfiguration and functionary impairment for patients. Emerging evidences demonstrated ADSC-Exo could alleviate the visce
Autor:
Wei Zhang, Juntao Han, Gaofeng Wu, Xiao-Qiang Li, Wenbin Jia, Zhenzhen Li, Dahai Hu, Yanhui Jia, Fu Han, Xiang He, Shichao Han, Yunshu Yang
Publikováno v:
Journal of Cellular Physiology. 234:16562-16572
Liver injury plays vital roles in the development of inflammation and organ dysfunction during sepsis. MCP-1-induced protein 1 (MCPIP1), as an endoribonuclease, is a critical regulator for the maintenance of immune homeostasis. However, whether MCPIP
Autor:
Yang Liu, Xiao-Qiang Li, Xujie Wang, Xiaozhi Bai, Shichao Han, Yanhui Jia, Dahai Hu, Jihong Shi, Kejia Wang, Mengyuan Cao, Julei Zhang, Fu Han
Publikováno v:
International Immunopharmacology. 63:220-226
MicroRNA-146a is a well-studied microRNA participating in immune and inflammatory diseases, but its role in sepsis has not been investigated. Here in our study, we found increased level of microRNA-146a in macrophage stimulated by lipopolysaccharide.
Publikováno v:
Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 69(3)
The present study sought to investigate the association between silent information regulator 1 (SIRT1) and autophagy during systemic inflammatory response syndrome following burn injury. The experimental burn model in mice and macrophages were establ
Autor:
Shichao Han, Fu Han, Dan Xiao, Dahai Hu, Xiao-Qiang Li, Yang Liu, Yanhui Jia, Xiaozhi Bai, Hao Guan, Zhenzhen Li, Weixia Cai, Kejia Wang
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1864:784-792
Molecular mechanisms for macrophage immune responses modulated by SIRT1 during sepsis remain unclear. Here, we show that SIRT1 expression is down-regulated in macrophages from mouse sepsis model or LPS stimulation. SIRT1 expression in macrophages cor
Autor:
Kuan Yang, Weixia Cai, Yanhui Jia, Yunshu Yang, Chen Yang, Xiaozhi Bai, Dahai Hu, Xiao-Qiang Li, Shichao Han, Ji Peng, Zhenzhen Li, Wanfu Zhang, Gaofeng Wu
Publikováno v:
Journal of cellular physiology. 234(12)
The severity of sepsis is associated with excessive inflammatory responses. MCP-1 induced protein (MCPIP1) could negatively regulate inflammatory responses by deubiquitinating K48 or K63 polyubiquitins of TNF receptor-associated factors. The function
Autor:
Zhenzhen Li, Su Linlin, Yanhui Jia, Fangfang Yang, Jian Zhang, Dahai Hu, Fu Han, Juntao Han, Kejia Wang, Xiao-Qiang Li, Shichao Han, Xujie Wang, Gaofeng Wu, Lu Bai, Hao Guan
Publikováno v:
Respiratory Physiology & Neurobiology. 281:103506
Acute lung injury (ALI) is one of the most severe outcomes of sepsis which still waiting for effective treatment method. Roxadustat (FG-4592) which is often used for treatment of anemia in patients with chronic kidney disease (CKD), its affection on
Autor:
Yanhui Jia, Dahai Hu, Xue Wu, Shichao Han, Jihong Shi, Linlin Su, Shan Shi, Yan Li, Jianxin Gao
Publikováno v:
Biomedicine & Pharmacotherapy. 80:80-86
Hypertrophic scar (HS) is a skin fibrotic disease that causes major clinically problematic symptoms. Cryptotanshinone (CT) is an important ingredient of Danshen (Salvia miltiorrhiza Bunge extract) that has been used to treat cardio-cerebral vascular
Autor:
Dahai Hu, Weixia Cai, Yanhui Jia, Xiao-Qiang Li, Xiaozhi Bai, Linlin Su, Gaofeng Wu, Zhenzhen Li, Wanfu Zhang, Kejia Wang, Fu Han
Publikováno v:
Archives of biochemistry and biophysics. 661
Objective Chronic wounds are a devastating complication of diabetes and can lead to amputations or even death. Current medical therapies are insufficient to accelerate its repair. The objective of this study was to explore the role of Sirtuin1 (SIRT1