Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Svetlana Fayngerts"'
Autor:
Gwendolyn K. Binder, Dejka M. Araujo, Daniel Nunez, Samik Basu, Luca Melchiori, Rafael G. Amado, Gareth Betts, Natalie Bath, Rebecca Dryer-Minnerly, Ruoxi Wang, Sandra P. D'Angelo, Mihaela Druta, Malini Iyengar, Albiruni Ryan Abdul Razak, Stephan A. Grupp, Breelyn A. Wilky, Jean Marc Navenot, George D. Demetri, Alex Tipping, Brian A. Van Tine, Erin Van Winkle, Warren Chow, Trupti Trivedi, Indu R. Ramachandran, Svetlana Fayngerts, Karen Chagin, Crystal L. Mackall, Daniel E. Lowther, John Glod
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-14 (2019)
Journal for immunotherapy of cancer, vol 7, iss 1
Journal for Immunotherapy of Cancer
Journal for immunotherapy of cancer, vol 7, iss 1
Journal for Immunotherapy of Cancer
Background Gene-modified autologous T cells expressing NY-ESO-1c259, an affinity-enhanced T-cell receptor (TCR) reactive against the NY-ESO-1-specific HLA-A*02-restricted peptide SLLMWITQC (NY-ESO-1 SPEAR T-cells; GSK 794), have demonstrated clinical
Autor:
Svetlana Fayngerts, David S. Hong, Francine Brophy, Ecaterina Ileana Dumbrava, Partow Kebriaei, Jean-Marc Navenot, Sarah Boross-Harmer, Amy Sauer, Matthew J. Frigault, Paula M. Fracasso, Ryan J. Sullivan, Elliot Norry, Marcus O. Butler, Jane Bai, Russell K. Pachynski
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background ADP-A2M10 SPEAR T-cells are genetically engineered autologous T-cells that express a high affinity MAGE-A10-specific T-cell receptor targeting MAGE-A10+tumors in the context of HLA A*02. This trial is no longer enrolling (NCT02989064). Met
Autor:
Mei Lin, Youhai H. Chen, Svetlana Fayngerts, Thomas Porturas, Honghong Sun, Weidong Xie, Terry Cathopoulis, Ali Zamani, Jason R. Goldsmith, Anastassios Vourekas, Amanda E. Boggs, Zhaojun Wang
Publikováno v:
Nature immunology
The polarization of leukocytes toward chemoattractants is essential for the directed migration (chemotaxis) of leukocytes. How leukocytes acquire polarity after encountering chemical gradients is not well understood. We found here that leukocyte pola
Autor:
Yunwei Lou, Svetlana Fayngerts, Derek S. Johnson, Thomas Porturas, Terry Cathopoulis, George Buchlis, Youhai H. Chen, Honghong Sun, Zhaojun Wang, Xiaohong Liang
Publikováno v:
The Journal of Immunology. 194:5743-5750
TNF-α–induced protein 8 (TNFAIP8 or TIPE) is a newly described regulator of cancer and infection. However, its precise roles and mechanisms of actions are not well understood. We report in this article that TNFAIP8 regulates Listeria monocytogenes
Autor:
Zhaojun Wang, Jianping Wu, Lining Zhang, Anastassios Vourekas, Honghong Sun, Camilla L. Oxley, Xianglan Liu, Svetlana Fayngerts, Yigong Shi, Jian Cui, Mark A. Lemmon, Suxia Liu, Youhai H. Chen, Terry Cathopoulis
Publikováno v:
Cancer Cell. (4):465-478
SummaryMore than half of human cancers have aberrantly upregulated phosphoinositide signals; yet how phospholipid signals are controlled during tumorigenesis is not fully understood. We report here that TIPE3 (TNFAIP8L3) is the transfer protein of ph