Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Stefano Gambardella"'
Autor:
Paola Lenzi, Rosangela Ferese, Francesca Biagioni, Michele Madonna, Fiona Limanaqi, Francesco Fornai, Stefano Gambardella
Publikováno v:
Brain Research. 1719:157-175
Methamphetamine (Meth) produces a variety of epigenetic effects in the brain, which are seminal to establish long-lasting alterations in neuronal activity. However, most epigenetic changes were described by measuring the rough amount of either histon
Autor:
Claudia Strafella, Valerio Caputo, Andrea Termine, Francesca Assogna, Clelia Pellicano, Francesco E. Pontieri, Lucia Macchiusi, Giulietta Minozzi, Stefano Gambardella, Diego Centonze, Paola Bossù, Gianfranco Spalletta, Carlo Caltagirone, Emiliano Giardina, Raffaella Cascella
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Frontiers in Genetics
Frontiers in Genetics
The present study investigated the association of SNPs involved in the regulation of immune response, cellular degenerative and neuroinflammatory pathways with the susceptibility and progression of idiopathic Parkinson’s Disease (PD). In particular
Autor:
Alice Traversa, Gioia Mastromoro, Carlo Di Bonaventura, Enrica Marchionni, Stefano Gambardella, Rosa Campopiano, Antonio Pizzuti
Publikováno v:
Neurodegenerative Diseases. 19:96-100
APP gene mutations causing Alzheimer disease (AD) segregate in an autosomal dominant pattern. We report on a 40-year-old woman with a severe cognitive decline starting at 36 years, while her affected relatives presented symptoms onset in the 6th deca
Autor:
Marco Castori, Marilena Carmela Di Giacomo, Leonardo D'Agruma, Grazia Nardella, Antonio Petracca, Carmela Fusco, Stefano Gambardella, Stefania Zampatti, Nicola Paciello, Silvia Lanfranconi, Lucia Micale, Dario Ronchi
Publikováno v:
Clinical geneticsREFERENCES. 99(6)
Cerebral cavernous malformation (CCM) is a vascular malformation of the central nervous system which may occur sporadically or segregate within families due to heterozygous variants in KRIT1/CCM1, MGC4607/CCM2 or PDCD10/CCM3. Intronic variants are no
Autor:
Rosangela Ferese, Stefania Zampatti, Carmelo D'Alessio, Francesca Biagioni, Mirco Fanelli, Stefano Gambardella, Stefano Amatori, Maria Antonietta Chiaravalloti, Emiliano Giardina, Cinzia Femiano, Diego Centonze, Fabio Buttari, Rosa Campopiano, Francesco Fornai, Marianna Storto
Publikováno v:
Genes
Volume 12
Issue 5
Genes, Vol 12, Iss 775, p 775 (2021)
Volume 12
Issue 5
Genes, Vol 12, Iss 775, p 775 (2021)
X-linked adrenoleukodystrophy (X-ALD, OMIM #300100) is the most common peroxisomal disorder clinically characterized by two main phenotypes: adrenomyeloneuropathy (AMN) and the cerebral demyelinating form of X-ALD (cerebral ALD). The disease is cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebb24b502ac9c70018df7d553fc10da4
http://hdl.handle.net/11568/1104080
http://hdl.handle.net/11568/1104080
Autor:
Filippo Sean Giorgi, Paola Lenzi, Stefano Gambardella, Stefano Ruggieri, Diego Centonze, Nicola Modugno, Rosangela Ferese, Francesco Fornai, Francesca Biagioni, Enrica Olivola
Publikováno v:
Journal of Neural Transmission
Peripheral markers in Parkinson’s disease (PD) represent a hot issue to provide early diagnosis and assess disease progression. The gold standard marker of PD should feature the same reliability as the pathogenic alteration, which produces the dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd5c968baa18fe58c0beec8fbbdf949a
http://hdl.handle.net/2108/282279
http://hdl.handle.net/2108/282279
Publikováno v:
Clinical Epigenetics
Background The oncogenic role of histone mutations is one of the most relevant discovery in cancer epigenetics. Recurrent mutations targeting histone genes have been described in pediatric brain tumors, chondroblastoma, giant cell tumor of bone and o
Autor:
Marianna Storto, Rosa Campopiano, Emiliano Giardina, Mirco Fanelli, Francesca Biagioni, Diego Centonze, Claudio Colonnese, Stefano Gambardella, Fabio Buttari, Vania Broccoli, Francesco Fornai, Edoardo Fraviga, Stefania Zampatti, Rosangela Ferese
Publikováno v:
BMC Neurology, Vol 20, Iss 1, Pp 1-6 (2020)
BMC Neurology
BMC Neurology
Background Leukodystrophies are familial heterogeneous disorders primarily affecting the white matter, which are defined as hypomyelinating or demyelinating based on disease severity as assessed at MRI. Recently, a group of clinically overlapping hyp
Autor:
Francesca De Vito, Andrea Paolillo, Antonio Uccelli, Mario Stampanoni Bassi, Roberto Furlan, Luana Gilio, Fabio Buttari, Stefano Gambardella, Ilaria Simonelli, Annamaria Finardi, Giuseppe Matarese, Diego Centonze, Marianna Storto, Rosangela Ferese, Girolama Alessandra Marfia, Marco Salvetti, Andrea Visconti
Publikováno v:
Genes, Vol 11, Iss 1152, p 1152 (2020)
Genes
Volume 11
Issue 10
Genes
Volume 11
Issue 10
In multiple sclerosis (MS), activated T and B lymphocytes and microglial cells release various proinflammatory cytokines, promoting neuroinflammation and negatively affecting the course of the disease. The immune response homeostasis is crucially reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f7a3fc200ac8d5705c32b933a6cafd0
http://hdl.handle.net/11573/1477836
http://hdl.handle.net/11573/1477836
Autor:
Marianna Storto, Carla L. Busceti, Rosangela Ferese, Francesco Fornai, Larisa Ryskalin, Emiliano Giardina, Stefania Zampatti, Stefano Gambardella, Francesca Biagioni, Rosa Campopiano
Publikováno v:
Archives Italiennes de Biologie. :159-166
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease clinically characterized by upper and lower motor neuron dysfunction resulting in rapidly progressive paralysis and death from respiratory failure. Most cases appear to be spora