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pro vyhledávání: '"Siwaporn Mitruk"'
Autor:
Siwaporn Mitruk, David M. Burger, Kanokrat Rungtivasuwan, Narukjaporn Thammajaruk, Kiat Ruxrungtham, Anchalee Avihingsanon, Baralee Punyawudho, Thitima Pengsuparp
Publikováno v:
Antimicrobial Agents and Chemotherapy, 59, 6, pp. 3240-5
Antimicrobial Agents and Chemotherapy, 59, 3240-5
Antimicrobial Agents and Chemotherapy, 59, 3240-5
Tenofovir (TFV) is eliminated by renal excretion, which is mediated through multidrug-resistant protein 2 (MRP2) and MRP4, encoded by ABCC2 and ABCC4 , respectively. Genetic polymorphisms of these transporters may affect the plasma concentrations of