Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sandrine Niyongere"'
Autor:
Amy E. DeZern, Alan F. List, Jeffrey E. Lancet, Hannah Newman, Eric Padron, Maria E. Balasis, Mikkael A. Sekeres, Rami S. Komrokji, Anthony M. Hunter, Qianxing Mo, Traci Kruer, Sandrine Niyongere, Markus Ball, Christopher Letson, Aaron T. Gerds, Gail J. Roboz, David A. Sallman, Hailing Zhang, Onyee Chan, David P. Steensma, William Dominguez-Viqueira
Publikováno v:
Clinical Cancer Research. 27:6095-6105
Purpose: Chronic myelomonocytic leukemia (CMML) is a rare leukemia characterized by peripheral monocytosis with no disease-modifying therapies. CMML cells are uniquely hypersensitive to granulocyte-macrophage colony-stimulating factor (GM-CSF) and ro
Autor:
Jonathan Cornu, Vu H. Duong, Alison Duffy, Maria R. Baer, Sandrine Niyongere, Jummai Apata, Ciera L Patzke, Noa G. Holtzman, Sarah M. Kashanian, Ashkan Emadi, Farin Kamangar, Madhurima Koka
Publikováno v:
Cancer Chemotherapy and Pharmacology. 87:817-826
Asparaginases, key agents in treatment of acute lymphoblastic leukemia (ALL), are associated with venous thromboembolism (VTE). While risks of short-acting asparaginase-related VTE is well-known, we studied VTE incidence and risk factors in adult ALL
Autor:
Maria R. Baer, Amol C. Shetty, Elizabeth T. Chang, Sandrine Niyongere, Erin T. Strovel, Rena G. Lapidus, Ronald B. Gartenhaus, Kayla M. Tighe, Bandish Kapadia, Brandon Carter-Cooper, Ashkan Emadi, Anup Mahurkar, Farin Kamangar, Binny Bhandary, Dominique R Bollino, Xinrong Ma, Eun Yong Choi, Curt I. Civin, Blake S. Moses, Hannah Kaizer
Publikováno v:
Leukemia. 35:1907-1924
Complex karyotype acute myeloid leukemia (CK-AML) has a dismal outcome with current treatments, underscoring the need for new therapies. Here, we report synergistic anti-leukemic activity of the BCL-2 inhibitor venetoclax (Ven) and the asparaginase f
Autor:
Mrinal M. Patnaik, Pierre Fenaux, Christophe Willekens, Philippe Rameau, Floriane Noel, Raphael Itzykson, Matthieu Duchmann, Nolwenn Lucas, Eric Solary, Paula Michea, M'Boyba Diop, Matthew T. Howard, Sandrine Niyongere, Rebecca L. King, Eric Padron, Vassili Soumelis, Michaela Fontenay, Martin E. Fernandez-Zapico, Gérard Pierron, Véronique Saada, Nathalie Droin, Vincent Ribrag, Olivier Kosmider
Publikováno v:
Leukemia. 33:2466-2480
Islands of CD123high cells have been commonly described in the bone marrow of patients with chronic myelomonocytic leukemia (CMML). Using a multiparameter flow cytometry assay, we detected an excess of CD123+ mononucleated cells that are lineage-nega
Autor:
Max An, Justin Lawson, Muhammad Safwan, Sandrine Niyongere, Maria R. Baer, Tahreem Iqbal, Vu H. Duong, Jennie Y. Law, Brian Barr, Gabriela Sanchez-Petitto, Michael E. Kallen, Ashkan Emadi, James Childress, Madhurima Koka, Jack Masur, Olga Goloubeva
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 21:S350-S351
Context: The incidence of both myeloid malignancies and cardiovascular disease (CVD) increases with age. We aimed to study whether the presence of CVD is associated with worse outcomes in patients with myeloid malignancies and to delineate a possible
Autor:
Sandrine Niyongere, Maria R. Baer, Gabriela Sanchez-Petitto, Jack Masur, Vu H. Duong, Ashkan Emadi
Publikováno v:
Pharmaceuticals
Pharmaceuticals, Vol 13, Iss 124, p 124 (2020)
Pharmaceuticals, Vol 13, Iss 124, p 124 (2020)
Outcomes of acute lymphoblastic leukemia (ALL) in older adults treated with chemotherapy are poor. The CD19/CD3 bispecific T-cell engager (BiTE) antibody blinatumomab is approved for refractory, relapsed or minimal/measurable residual disease (MRD)-p
Autor:
Sandrine Niyongere, Michael W. Deininger, Brooke L. Fridley, Qing Zhang, Yu Long Zhao, John Robinson, Samer S. Sansil, Eric Padron, Rami S. Komrokji, Eric Solary, Alan F. List, Markus Ball, Valeria Santini, Junmin Zhou, Jodi L. Kroeger, Anthony D. Pomicter, Maria E. Balasis, Nolwenn Lucas
Publikováno v:
Leukemia
Chronic myelomonocytic leukemia (CMML) is a clinically heterogeneous neoplasm in which JAK2 inhibition has demonstrated reductions in inflammatory cytokines and promising clinical activity. We hypothesize that annotation of inflammatory cytokines may
Publikováno v:
Journal of Thoracic Disease. 10:S433-S450
Immune checkpoint inhibitors enhance the activation and antitumor activity of the immune system, resulting in durable response rates in a select group of patients. Cytotoxic T lymphocyte antigen 4 (CTLA4) inhibitors target the inhibitory interaction
Autor:
Max An, Justin Lawson, James Childress, Jack Masur, Brian Barr, Maria R. Baer, Jasmin Sahbaz, Sandrine Niyongere, Vu H. Duong, Tahreem Iqbal, Safwan Muhammad, Gabriela Sanchez-Petitto, Jennie Y. Law, Olga Goloubeva, Ashkan Emadi
Publikováno v:
Blood. 136:37-38
Background: The incidence of both myeloid malignancies and cardiovascular disease (CVD) increases with age, and cardiac disease is the most frequent cause of non-hematologic morbidity in patients with myelodysplastic syndrome (MDS). We aimed to study
Autor:
Vu Doung, Ashkan Emadi, Maria R. Baer, Sandrine Niyongere, Emily J. Vannorsdall, Zeba N. Singh, Yamini Kathari
Publikováno v:
Blood. 136:6-7
Background: Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder with features of both myeloproliferative neoplasm and myelodysplastic syndrome (MDS). CMML is characterized by persistent blood monocytosis >1 x 109/L, bo