Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Pengfei Jiang"'
Autor:
Clayton T. Cuddington, Katelyn E Swindle-Reilly, Pengfei Jiang, Francisco J. Chaparro, Matthew Ohr, Andre F. Palmer, John J. Lannutti
Publikováno v:
Journal of Controlled Release. 320:442-456
Vascular endothelial growth factor (VEGF) is a key regulator of abnormal blood vessel growth. As such, bevacizumab-based inhibition of VEGF has been the clinically adopted strategy to treat colorectal and breast cancers as well as age-related macular
Autor:
Kanwal M. Farooqi, Brett R. Anderson, Erika B. Rosenzweig, Amee Shah, Usha Krishnan, Junhui Mi, Pengfei Jiang, Michael P. DiLorenzo, Elizabeth Abrahams, Angela Chan, Nikhil Pasumarti, Anne Ferris, Philip Zachariah, Mark Gorelik, Sanghee Suh, Rachel Weller, Joshua D. Milner
Publikováno v:
Pediatrics. 148
BACKGROUND In spring 2020, a novel hyperinflammatory process associated with severe acute respiratory syndrome coronavirus 2 multisystem inflammatory syndrome in children (MIS-C) was described. The long-term impact remains unknown. We report longitud
Autor:
Xiaoying Yang, Weimin Ding, Xinyu Qian, Pengfei Jiang, Qingqing Chen, Xin Zhang, Yang Lu, Jiacheng Wu, Fenfen Sun, Zhihua Pan, Xiangyang Li, Wei Pan
Publikováno v:
Frontiers in Veterinary Science
Frontiers in Veterinary Science, Vol 8 (2021)
Frontiers in Veterinary Science, Vol 8 (2021)
The deposition of Schistosoma japonicum (S. japonicum) eggs commonly induces inflammation, fibrosis, hyperplasia, ulceration, and polyposis in the colon, which poses a serious threat to human health. However, the underlying mechanism is largely negle
Publikováno v:
Analytica chimica acta. 1154
Cancer severely threatens human health currently, promoting the rapid development of cancer treatment strategies. In addition to cancer therapy, assessment of cancer prognosis, which can evaluate the success with treatment and chances of recovery as
Publikováno v:
Nanoscale. 12(33)
Reactive oxidative species (ROS) are the primary mediator of angiogenesis by upregulating the expression of vascular endothelial growth factor (VEGF) in the development of wet age-related macular degeneration (AMD). However, the current treatment of
Publikováno v:
International ophthalmology. 41(6)
To evaluate whether anti-vascular endothelial growth factor (VEGF) therapy combined with panretinal photocoagulation could reverse diabetic retinopathy (DR). Fifty-two patients (72 eyes) with high-risk proliferative DR who were diagnosed and treated
Autor:
Jinshun Zhu, Xingyuan Ci, Lifang Zhang, Pengfei Jiang, Shao Chen, Wanlin Tang, Meiping Gu, Shanli Zhu, Danwei Cen, Saidu Kamara, Lude Wang, Jun Chen, Xiangyang Xue
Publikováno v:
Cell Death and Disease, Vol 11, Iss 6, Pp 1-1 (2020)
Cell Death & Disease
Cell Death & Disease
Nasopharyngeal carcinoma (NPC) induced by latent infection with Epstein-Barr virus (EBV) remains the most common head and neck cancer in Southeast Asia, especially in the southern part of China. It is well known that persistent expression of two EBV
Publikováno v:
BMC Ophthalmology, Vol 21, Iss 1, Pp 1-9 (2021)
BMC Ophthalmology
BMC Ophthalmology
Background Retinal degeneration is often accompanied by microglia-mediated neuroinflammation. Ferulic acid (FA), an active ingredient of traditional Chinese medicines (TCMs), has been reported to have anti-inflammatory effects. This study explores th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc46b3baf4f606ebf2d8b42102d5cd53
https://doi.org/10.21203/rs.2.24503/v2
https://doi.org/10.21203/rs.2.24503/v2
Autor:
Nam-Gu Her, Pengfei Jiang, Santosh Kesari, Elmar Nurmemmedov, Venkata Mahidhar Yenugonda, Rajesh Mukthavaram, Natsuko Nomura, Jatin Roper, Ivan Babic, Anton Cheltsov
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Abnormal regulation of β-catenin initiates an oncogenic program that serves as a main driver of many cancers. Albeit challenging, β-catenin is an attractive drug target due to its role in maintenance of cancer stem cells and potential to eliminate
Autor:
Jiaping He, Xun Ye, Nanjing Lin, Yuezhang Chen, Yan Wu, Songbai Cai, Junfang Yang, Xian Zhang, Zhenguang Wang, Li Xu, Jingjing Li, Xiaoyan Zhao, Qi Dong, Xiaona Hu, Martina Sersch, Pengfei Jiang, Yunchao Su, Wei Cao, Peihua Lu
Publikováno v:
Blood. 136:2-3
Introduction Multiple issues arise for a wider application of chimeric antigen receptor (CAR) T cell therapy including manufacturing time and antigen escape. Here we report data on an anti-CD19/CD22 dual CAR-T (GC022F) therapy based on a novel manufa