Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Michel Laviolette"'
Autor:
Salman Siddiqui, Adalberto Sperb Rubin, José Roberto Lapa e Silva, Jennifer L. Olson, Kaharu Sumino, Charlene McEvoy, G. Mark Grubb, Michel Laviolette, Rekha Chaudhuri, Karin Klooster, Edmund McMullen, Sumita Khatri, Robert Niven, Richard G. Barbers, Michael Simoff, Pallav L. Shah
Publikováno v:
The Lancet. Respiratory Medicine, 9(5), 457-466. ELSEVIER SCI LTD
Methods BT10+ was an international, multicentre, follow-up study of participants who were previously enrolled in the AIR, RISA, and AIR2 trials and who had 10 or more years of follow-up since bronchial thermoplasty treatment. Data on patient demograp
Autor:
Amine Cheikh, Étienne Doré, Cyril Martin, Anne-Sophie Archambault, Y. Tijani, Hakima Fares, Eric Boilard, Michel Laviolette, Isabelle Dubuc, Youssef Amar, Louis Flamand, Olivier Flamand, Amine El Hassani, Volatiana Rakotoarivelo, Nicolas Flamand, Andréanne Côté, Younes Zaid, Caroline Turcotte
Publikováno v:
The FASEB Journal
Severe acute respiratory syndrome coronavirus 2 is responsible for coronavirus disease 2019 (COVID‐19). While COVID‐19 is often benign, a subset of patients develops severe multilobar pneumonia that can progress to an acute respiratory distress s
Autor:
Michel Laviolette, Isabelle Dubuc, Anne-Sophie Archambault, Amine El Hassani, Amine Cheikh, Étienne Doré, Younes Zaid, Hakima Fares, Louis Flamand, Cyril Martin, Eric Boilard, Volatiana Rakotoarivelo, Youssef Amar, Y. Tijani, Nicolas Flamand
BACKGROUNDSevere Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) is the infectious agent responsible for Coronavirus disease 2019 (COVID-19). While SARS-CoV-2 infections are often benign, there are also severe COVID-19 cases, characterized by s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bb06fa722131d61a584b2bb97628f53
https://doi.org/10.1101/2020.12.04.20242115
https://doi.org/10.1101/2020.12.04.20242115
Autor:
Jennifer Lamothe, Krystelle Godbout, Aida Eslami, Kim Valette, David C. Nickle, Arnaud Chignon, Andréanne Côté, Maarten van den Berge, Don D. Sin, Patrick Mathieu, Michel Laviolette, Zhonglin Li, Valentin Bon-Baret, Ke Hao, Yohan Bossé, Nathalie Gaudreault, Catherine Labbé, Jean-Christophe Bérubé, Philippe Joubert, Ma'en Obeidat, Sébastien Thériault, Louis-Philippe Boulet, Wim Timens
To identify susceptibility loci and candidate causal genes of asthma, we performed a genome-wide association study (GWAS) in UK Biobank on a broad asthma definition (n = 56,167 asthma cases and 352,255 controls). We then carried out functional mappin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf5dfe91f5e9c57dbf62c71df0df0cea
https://doi.org/10.21203/rs.3.rs-68257/v1
https://doi.org/10.21203/rs.3.rs-68257/v1
Autor:
Ma'en Obeidat, Krystelle Godbout, Kim Valette, Philippe Joubert, Louis-Philippe Boulet, Sébastien Thériault, Maarten van den Berge, Patrick Mathieu, Arnaud Chignon, Catherine Labbé, Valentin Bon-Baret, Jean-Christophe Bérubé, Jennifer Lamothe, Nathalie Gaudreault, Aida Eslami, David C. Nickle, Ke Hao, Don D. Sin, Zhonglin Li, Michel Laviolette, Wim Timens, Andréanne Côté, Yohan Bossé
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications biology, 4(1):700. Nature Publishing Group
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications biology, 4(1):700. Nature Publishing Group
To identify candidate causal genes of asthma, we performed a genome-wide association study (GWAS) in UK Biobank on a broad asthma definition (n = 56,167 asthma cases and 352,255 controls). We then carried out functional mapping through transcriptome-
Autor:
Michel Laviolette, Daiana Stolz, Peter I. Bonta, Jamila Chakir, Marina Pretolani, Christopher E. Brightling, Michel Aubier, Mario Castro, Rekha Chaudhuri, Desiree Schumann, Latifa Chachi, Peter H. Howarth, Pascal Chanez, Jouke T. Annema, Amisha Singapuri, Richard J. Russell
Publikováno v:
Airway pharmacology and treatment.
Background: Bronchial Thermoplasty (BT) reduces exacerbations and improves asthma quality of life questionnaire (AQLQ) scores in asthma [1]. Studies have shown reductions in airway smooth muscle (ASM) mass and reticular basement membrane (RBM) thickn
Autor:
Michel Laviolette, Isabelle Dubuc, Younes Zaid, Nicolas Flamand, Louis Flamand, Olivier Flamand, Anne Sophie Archambault, Étienne Doré, Eric Boilard
Publikováno v:
The Journal of Allergy and Clinical Immunology
Background Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection can lead to a variety of clinical outcomes ranging from the absence of symptoms to severe acute respiratory disease and ultimately death. A feature of patients with sev
Autor:
J. Mark FitzGerald, Richard Leigh, Joel N. Kline, Stephen Lam, Matthew J. Loza, Andreas Eich, Frédéric Baribaud, Patrick Berger, P. Chanez, Philip E. Silkoff, Dave Singh, Vedrana S. Susulic, Steven G. Kelsen, Elliot S. Barnathan, Michel Laviolette, Azra Hussaini, Irina Strambu, William J. Calhoun, Andrea Ludwig-Sengpiel, Geoffrey Chupp, Mark T. Dransfield, Vibeke Backer, Pierre Olivier Girodet, Celeste Porsbjerg
Publikováno v:
Journal of Allergy and Clinical Immunology. 140:710-719
Background The Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study profiled patients with mild, moderate, and severe asthma and nonatopic healthy control subjects. Objective We explored this data set to define type 2 inflammation b
Autor:
Michel Laviolette, Suzanne Maahs, Veronica A. Swystun, Louis-Philippe Boulet, Irvin Mayers, Christopher Carlsten, Philip J. Lowe, Barbro Dahlén, Andrej Skerjanec, Miranda Bowen, Richard Leigh, Linda Hui, Beth E. Davis, Richard M. Watson, Gail M. Gauvreau, Kieran J. Killian, Joanne Milot, Anton Drollmann, Paul M. O'Byrne, J. Mark FitzGerald, Ann-Sofie Lantz, Karin Meiser, Nikolaos Lazarinis, Jonathan P. Arm, Donald W. Cockcroft
Publikováno v:
Journal of Allergy and Clinical Immunology. 138:1051-1059
Background Omalizumab is an established anti-IgE therapy for the treatment of allergic diseases that prevents IgE from binding to its receptor. QGE031 is an investigational anti-IgE antibody that binds IgE with higher affinity than omalizumab. Object
Autor:
Don D. Sin, Ke Hao, Philippe Joubert, Michel Laviolette, Yohan Bossé, Wim Timens, Dirkje S. Postma, David C. Nickle, Maxime Lamontagne, Peter D. Paré
Publikováno v:
European Respiratory Journal, 48(2), 573-576. EUROPEAN RESPIRATORY SOC JOURNALS LTD
The major histocompatibility complex (MHC) has been linked with hundreds of diseases [1]. The MHC is one of the most complex regions of the human genome, because of the high gene density, extended linkage disequilibrium (LD) and sequence diversity [2