Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Martin Tepel"'
Publikováno v:
Kidney International Reports
Nagarajah, S, Rasmussen, M, Hoegh, S V & Tepel, M 2020, ' Prospective Study of Long Non-Coding RNA, MGAT3-AS1, and Viremia of BK Polyomavirus and Cytomegalovirus in Living Donor Renal Transplant Recipients ', Kidney International Reports, vol. 5, no. 12, pp. 2218-2227 . https://doi.org/10.1016/j.ekir.2020.09.005
Nagarajah, S, Rasmussen, M, Hoegh, S V & Tepel, M 2020, ' Prospective Study of Long Non-Coding RNA, MGAT3-AS1, and Viremia of BK Polyomavirus and Cytomegalovirus in Living Donor Renal Transplant Recipients ', Kidney International Reports, vol. 5, no. 12, pp. 2218-2227 . https://doi.org/10.1016/j.ekir.2020.09.005
Introduction Viremia after renal transplantation is a major cause of morbidity and mortality and treatment opportunities are limited. Tests to determine the increased risk for viremia would be preferable. Methods In a prospective, single-center study
Publikováno v:
Heliyon, Vol 7, Iss 12, Pp e08489-(2021)
Saleh, Q W, Grønbæk, L, Kronborg, C, Lauridsen, J T & Tepel, M 2021, ' Kidney function, future health costs, and quality-adjusted life-years in kidney transplant recipients transplanted during the SARS-Cov-2 lockdown in Denmark : An observational study ', Heliyon, vol. 7, no. 12, e08489 . https://doi.org/10.1016/j.heliyon.2021.e08489
Heliyon
Saleh, Q W, Grønbæk, L, Kronborg, C, Lauridsen, J T & Tepel, M 2021, ' Kidney function, future health costs, and quality-adjusted life-years in kidney transplant recipients transplanted during the SARS-Cov-2 lockdown in Denmark : An observational study ', Heliyon, vol. 7, no. 12, e08489 . https://doi.org/10.1016/j.heliyon.2021.e08489
Heliyon
Background It is unknown whether lockdown due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may affect both clinical outcome in kidney transplant recipients and health care economics in Denmark. Methods We compared kidney transplant
Autor:
Christian Nielsen, Subagini Nagarajah, Martin Tepel, Yaseelan Palarasah, Kristian Assing, Lotte Borg Lange, Lise Lotte Torvin Andersen, Claus Bistrup
Publikováno v:
BMC Nephrology, Vol 20, Iss 1, Pp 1-5 (2019)
BMC Nephrology
Nagarajah, S, Tepel, M, Nielsen, C, Assing, K, Palarasah, Y, Andersen, L L T, Lange, L B & Bistrup, C 2019, ' Reduced membrane attack complex formation in umbilical cord blood during Eculizumab treatment of the mother : A case report ', BMC Nephrology, vol. 20, 307 . https://doi.org/10.1186/s12882-019-1469-9
BMC Nephrology
Nagarajah, S, Tepel, M, Nielsen, C, Assing, K, Palarasah, Y, Andersen, L L T, Lange, L B & Bistrup, C 2019, ' Reduced membrane attack complex formation in umbilical cord blood during Eculizumab treatment of the mother : A case report ', BMC Nephrology, vol. 20, 307 . https://doi.org/10.1186/s12882-019-1469-9
Background: Atypical hemolytic uremic syndrome (aHUS) is a disorder of the microvasculature with hemolytic anemia, thrombocytopenia and acute kidney injury. Nowadays, aHUS is successfully treated with eculizumab, a humanized, chimeric IgG2/4 kappa an
Publikováno v:
Nagarajah, S, Xia, S, Rasmussen, M & Tepel, M 2019, ' Endogenous intronic antisense long non-coding RNA, MGAT3-AS1, and kidney transplantation ', Scientific Reports, vol. 9, 14743 . https://doi.org/10.1038/s41598-019-51409-0
Scientific Reports, Vol 9, Iss 1, Pp 1-7 (2019)
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-7 (2019)
Scientific Reports
β-1,4-mannosylglycoprotein 4-β-N-acetylglucosaminyltransferase (MGAT3) is a key molecule for the innate immune system. We tested the hypothesis that intronic antisense long non-coding RNA, MGAT3-AS1, can predict delayed allograft function after kid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cffc085743022304bc344ab175667191
https://findresearcher.sdu.dk:8443/ws/files/155523764/Endogenous_intronic_antisense_long_non_coding_RNA_MGAT3_AS1_and_kidney_transplantation.pdf
https://findresearcher.sdu.dk:8443/ws/files/155523764/Endogenous_intronic_antisense_long_non_coding_RNA_MGAT3_AS1_and_kidney_transplantation.pdf
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2017 (2017)
Shen, J, Rasmussen, M, Dong, Q-R, Tepel, M & Scholze, A 2017, ' Expression of the NRF2 Target Gene NQO1 Is Enhanced in Mononuclear Cells in Human Chronic Kidney Disease ', Oxidative Medicine and Cellular Longevity, vol. 2017, 9091879 . https://doi.org/10.1155/2017/9091879
Shen, J, Rasmussen, M, Dong, Q-R, Tepel, M & Scholze, A 2017, ' Expression of the NRF2 Target Gene NQO1 Is Enhanced in Mononuclear Cells in Human Chronic Kidney Disease ', Oxidative Medicine and Cellular Longevity, vol. 2017, 9091879 . https://doi.org/10.1155/2017/9091879
Reduced nuclear factor erythroid 2-related factor 2 (NRF2) pathway activity was reported in models of chronic kidney disease (CKD). Pharmacological activation of NRF2 is supposed to improve renal function, but data concerning the NRF2 activity in hum
Autor:
Signe Holm Nielsen, Morten A. Karsdal, Daniel Guldager Kring Rasmussen, Federica Genovese, Lene Boesby, Anne Lise Kamper, Martin Tepel, Sophie Birot
Publikováno v:
Rasmussen, D G K, Boesby, L, Nielsen, S H, Tepel, M, Birot, S, Karsdal, M A, Kamper, A L & Genovese, F 2019, ' Collagen turnover profiles in chronic kidney disease ', Scientific Reports, vol. 9, no. 1, 16062 . https://doi.org/10.1038/s41598-019-51905-3
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Rasmussen, D G K, Boesby, L, Nielsen, S H, Tepel, M, Birot, S, Karsdal, M A, Kamper, A L & Genovese, F 2019, ' Collagen turnover profiles in chronic kidney disease ', Scientific Reports, vol. 9, 16062 . https://doi.org/10.1038/s41598-019-51905-3
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Rasmussen, D G K, Boesby, L, Nielsen, S H, Tepel, M, Birot, S, Karsdal, M A, Kamper, A L & Genovese, F 2019, ' Collagen turnover profiles in chronic kidney disease ', Scientific Reports, vol. 9, 16062 . https://doi.org/10.1038/s41598-019-51905-3
Renal fibrosis is a hallmark of chronic kidney disease (CKD) caused by an imbalance between formation and degradation of extracellular matrix proteins. We investigated the collagen turnover profile of 81 non-dialysis CKD stage 2–5 patients by measu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b324ad8fa700719079c09a0635c402
https://orbit.dtu.dk/en/publications/c70f20d9-b04b-495c-a8fa-f9218a80e6e7
https://orbit.dtu.dk/en/publications/c70f20d9-b04b-495c-a8fa-f9218a80e6e7
Autor:
Gangyi Yang, Peng Gao, Lijuan Wang, Daoyan Liu, Zongshi Lu, Hexuan Zhang, Martin Tepel, Huan Ma, Fang Sun, Zhiming Zhu, Zhencheng Yan, Li Li, Xiao Wei, Yingru Hu, Hongting Zheng
Publikováno v:
Wei, X, Lu, Z, Li, L, Zhang, H, Sun, F, Ma, H, Wang, L, Hu, Y, Yan, Z, Zheng, H, Yang, G, Liu, D, Tepel, M, Gao, P & Zhu, Z 2020, ' Reducing NADPH Synthesis Counteracts Diabetic Nephropathy through Restoration of AMPK Activity in Type 1 Diabetic Rats ', Cell Reports, vol. 32, no. 13, 108207 . https://doi.org/10.1016/j.celrep.2020.108207
Diabetic nephropathy (DN) is a major complication of diabetes mellitus and a primary cause of end-stage renal failure. Clinical studies indicate that metabolic surgery improves DN; however, the mechanism remains unclear. Here, we report that Roux-en-
Autor:
Martin Tepel, Joachim Jankowski, Carola G. Schipke, Gary A. Brook, Oliver Peters, Anand Goswami, Eleonora Aronica, Vera Jankowski, Heidi Noels, Joachim Weis, Jasper J. Anink, Stefan Fritz, Felix Kork, Alfred Yamoah, Carmen Huck
Publikováno v:
Kork, F, Jankowski, J, Goswami, A, Weis, J, Brook, G, Yamoah, A, Anink, J, Aronica, E, Fritz, S, Huck, C, Schipke, C, Peters, O, Tepel, M, Noels, H & Jankowski, V 2018, ' Golgin A4 in CSF and granulovacuolar degenerations of patients with Alzheimer disease ', Neurology, vol. 91, no. 19, pp. e1799-e1808 . https://doi.org/10.1212/WNL.0000000000006457
Neurology, 91(19), e1799-e1808. Lippincott Williams and Wilkins
Neurology 91(19), e1799-e1808 (2018). doi:10.1212/WNL.0000000000006457
Neurology, 91(19), E1799-E1808. LIPPINCOTT WILLIAMS & WILKINS
Neurology, 91(19), e1799-e1808. Lippincott Williams and Wilkins
Neurology 91(19), e1799-e1808 (2018). doi:10.1212/WNL.0000000000006457
Neurology, 91(19), E1799-E1808. LIPPINCOTT WILLIAMS & WILKINS
ObjectiveTo isolate and identify a new, as yet unknown molecule in CSF that could serve as marker for Alzheimer disease.MethodsWe immunized mice with human CSF and fused hybridomas for monoclonal antibodies and screened these antibodies for their cap
Publikováno v:
Skarphedinsson, S, Thiesson, H C, Shakar, S A & Tepel, M 2015, ' Factors predicting kidney damage in Puumala virus infected patients in Southern Denmark ', European Journal of Clinical Microbiology & Infectious Diseases, vol. 34, no. 10, pp. 2017-21 . https://doi.org/10.1007/s10096-015-2446-2
Skarphedinsson, S, Thiesson, H C, Shakar, S A & Tepel, M 2015, ' Factors predicting kidney damage in Puumala virus infected patients in Southern Denmark ', European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, vol. 34, no. 10, pp. 2017-2021 . https://doi.org/10.1007/s10096-015-2446-2
Skarphedinsson, S, Thiesson, H C, Shakar, S A & Tepel, M 2015, ' Factors predicting kidney damage in Puumala virus infected patients in Southern Denmark ', European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, vol. 34, no. 10, pp. 2017-2021 . https://doi.org/10.1007/s10096-015-2446-2
In Europe, infections with Puumala hantavirus cause nephropathia epidemica. Presently the risk factors predicting severe kidney damage after Puumala virus infection are not well known. The objective of the study was to investigate environmental and i
Autor:
Martin Tepel, Lutz Renders, Amke Caliebe, Anneke N. Werk, Thorsten Feldkamp, Henrike Bruckmueller, Ulrich Kunzendorf, Ingolf Cascorbi, Christoffer Borst
Publikováno v:
ResearcherID
Bruckmueller, H, Werk, A N, Renders, L, Feldkamp, T, Tepel, M, Borst, C, Caliebe, A, Kunzendorf, U & Cascorbi, I 2015, ' Which genetic determinants should be considered for tacrolimus dose optimization in kidney transplantation? A combined analysis of genes affecting the CYP3A locus ', Therapeutic Drug Monitoring, vol. 37, no. 3, pp. 288-295 . https://doi.org/10.1097/FTD.0000000000000142
Bruckmueller, H, Werk, A N, Renders, L, Feldkamp, T, Tepel, M, Borst, C, Caliebe, A, Kunzendorf, U & Cascorbi, I 2015, ' Which genetic determinants should be considered for tacrolimus dose optimization in kidney transplantation? A combined analysis of genes affecting the CYP3A locus ', Therapeutic Drug Monitoring, vol. 37, no. 3, pp. 288-295 . https://doi.org/10.1097/FTD.0000000000000142
Background: Tacrolimus is established as immunosuppressant after kidney transplantation. Polymorphism of the cytochrome P450 3A5 (CYP3A5) gene contributes significantly to tacrolimus dose requirements. Recently, CYP3A4*22 was reported to additionally