Zobrazeno 1 - 10
of 302
pro vyhledávání: '"Jeffrey W. Clark"'
Autor:
Janet E. Murphy, David P. Ryan, Samuel J. Klempner, Joseph W. Franses, Madeleine Fish, Aparna Raj Parikh, Jon Dubois, Emily E. Van Seventer, Jill N. Allen, Theodore S. Hong, Katie Kanter, Lawrence S. Blaszkowsky, Eric Roeland, Jennifer Y. Wo, Jeffrey W. Clark, Bruce J. Giantonio, Colin D. Weekes, Ryan B. Corcoran, Ryan D. Nipp, Lipika Goyal, Nora Horick, Gianluca Mauri
Publikováno v:
JCO Oncology Practice. 17:e1846-e1855
PURPOSE: Colorectal cancer (CRC) incidence in patients younger than 50 years of age, commonly defined as early-onset (EO-CRC), is rising. EO-CRC often presents with distinct clinicopathologic features. However, data on prognosis are conflicting and o
Autor:
Jeffrey W. Clark, Lauren Matlack, Sanya Arshad, Ryan B. Corcoran, Aparna Raj Parikh, Benjamin D. Greenbaum, Colin D. Weekes, Michael J. Raabe, Lorraine C. Drapek, Jon Dubois, Theodore S. Hong, David P. Ryan, David T. Ting, Lipika Goyal, Bronwen Foreman, Bruce J. Giantonio, Leilana Ly, Hannah Thel, Arnav Mehta, Lawrence S. Blaszkowsky, Nir Hacohen, Andrew X. Zhu, Jennifer Y. Wo, David Hoyos, Ryan D. Nipp, Emily E. Van Seventer, Jill N. Allen, Annamaria Szabolcs, Jessica A. Meurer, David J. Lieb, Beow Y. Yeap
Publikováno v:
Nature Cancer. 2:1124-1135
Overcoming intrinsic resistance to immune checkpoint blockade for microsatellite stable (MSS) colorectal cancer (CRC) and pancreatic ductal adenocarcinoma (PDAC) remains challenging. We conducted a single-arm, non-randomized, phase II trial (NCT03104
Autor:
Colin D. Weekes, James C. Cusack, Christine E. Eyler, Lipika Goyal, Jochen K. Lennerz, Emily E. Van Seventer, Jill N. Allen, Jennifer Y. Wo, Peter J. Ulintz, Andrew X. Zhu, Hui Zheng, Susan G.R. McDuff, Theodore S. Hong, Daniel Kim, David P. Ryan, Mehlika Hazar-Rethinam, Jeffrey W. Clark, Ryan B. Corcoran, Isobel J Fetter, Brandon Nadres, Lawrence S. Blaszkowsky, Aparna Raj Parikh, Karin M. Hardiman
Publikováno v:
JCO Precis Oncol
PURPOSE This study was designed to assess the ability of perioperative circulating tumor DNA (ctDNA) to predict surgical outcome and recurrence following neoadjuvant chemoradiation for locally advanced rectal cancer (LARC). MATERIALS AND METHODS Twen
Autor:
Jennifer Y. Wo, Anushri Parakh, Yoshifumi Noda, Theodore S. Hong, Keith D. Lillemoe, Nisanard Pisuchpen, Nathaniel D. Mercaldo, Theodoros Michelakos, Motaz Qadan, Avinash Kambadakone, David P. Ryan, Carlos Fernandez-del Castillo, Jeffrey W. Clark, Yurie Sekigami, Cristina R. Ferrone
Publikováno v:
European Radiology. 32:2470-2480
To derive a CT-based scoring system incorporating arterial involvement and resectability status to predict R0 resection in patients with pancreatic ductal adenocarcinoma (PDAC) undergoing neoadjuvant chemoradiation therapy (CRT). This retrospective s
Autor:
Christine E. Eyler, Lorraine C. Drapek, Nora Horick, Jeffrey W. Clark, David H. Berger, David P. Ryan, Sam Klempner, Grace M. Lee, Aparna Raj Parikh, Daniel Kim, Florence K. Keane, Eric Roeland, John T. Mullen, Theodore S. Hong, Jennifer Y. Wo, Guichao Li, Jill N. Allen
Publikováno v:
Annals of Surgical Oncology. 29:242-252
The optimal timing of chemoradiotherapy (CRT) for patients with localized gastric cancer remains unclear. This study aimed to compare the survival outcomes between neoadjuvant and postoperative CRT for patients with gastric and gastroesophageal junct
Autor:
Kavel H. Visrodia, Jeffrey W. Clark, Thomas E. Clancy, David P. Ryan, Kumar Krishnan, Aparna Raj Parikh, Motaz Qadan, Andrew L. Warshaw, Douglas A. Rubinson, Lipika Goyal, Carlos Fernandez-del Castillo, Keith D. Lillemoe, Yasmin G. Hernandez-Barco, Vishwajith Sridharan, Kimberly Perez, Fateh Bazerbachi, Mari Mino-Kenudson, Brenna Casey, Osama E. Rahma, James M. Cleary, Cristina R. Ferrone
Publikováno v:
Pancreatology. 21:1119-1126
Acinar cell carcinoma (ACC) is a very rare tumor of the exocrine pancreas, representing less than 1% of all pancreatic malignancies. The majority of data regarding ACC are limited to small case series.This is a retrospective study conducted at a larg
Autor:
David Groshar, Jennifer Y. Wo, Motaz Qadan, Krista E Suarez-Weiss, James C. Cusack, Heike E. Daldrup-Link, Ricciardi Rocco, Amirkasra Mojtahed, Robin Striar, Liliana Bordeianou, Lale Umutlu, Felipe S. Furtado, Mark Anderson, Mark Vangel, Onofrio A. Catalano, Cristina R. Ferrone, Lawrence S. Blaszkowsky, Theodore S. Hong, Jeffrey W. Clark
Publikováno v:
Br J Cancer
Background Oligometastatic colorectal cancer (CRC) is potentially curable and demands individualised strategies. Methods This single-centre retrospective study investigated if positron emission tomography (PET)/magnetic resonance imaging (MR) had a c
Autor:
Jennifer Y. Wo, Ryan D. Nipp, David P. Ryan, Emily E. Van Seventer, Lawrence S. Blaszkowsky, Jill N. Allen, Heather A. Shahzade, James C. Cusack, Yupeng He, Hiroko Kunitake, Liliana Bordeianou, Lipika Goyal, Motaz Qadan, Samuel J. Klempner, Jon Dubois, Kathryn Fosbenner, AmirAli Talasaz, Benchun Miao, Cristina R. Ferrone, Bruce J. Giantonio, John H. Carmichael, Jeffrey W. Clark, Victoria M. Raymond, Susannah T. Phillips, Yojan S. Shah, Islam Baiev, Aparna Raj Parikh, Colin D. Weekes, Ariel Jaimovich, Genevieve M. Boland, Ryan B. Corcoran, David H. Berger, Joy X. Jarnagin, Katie Kanter, Nihaarika Sharma, Giulia Siravegna, Isobel J Fetter, Madeleine Fish, Theodore S. Hong, Eric Roeland, Joseph W. Franses, Rocco Ricciardi, Anna Hartwig
Publikováno v:
Clinical Cancer Research. 27:5586-5594
Purpose: Detection of persistent circulating tumor DNA (ctDNA) after curative-intent surgery can identify patients with minimal residual disease (MRD) who will ultimately recur. Most ctDNA MRD assays require tumor sequencing to identify tumor-derived
Autor:
Uvette Lou, Lawrence S. Blaszkowsky, Vineet K. Raghu, Sean P. Murphy, John W. Clark, Zsofia D. Drobni, Erica Tavares, Ramya C. Mosarla, Hannah K Gilman, Raza M. Alvi, Maeve Jones-O'Connor, Tomas G. Neilan, Colin D. Weekes, Sarah Hartmann, Amna Zafar, Matthew Lei, Jeffrey W. Clark
Publikováno v:
JACC: CardioOncology. 3:101-109
Background Coronary vasospasm is a recognized side effect of 5-fluorouracil (5-FU). There are limited and conflicting data on the incidence, risk factors, and prognostic effect of 5-FU–associated vasospasm. Objectives This study sought to assess th
Autor:
Aparna Raj Parikh, Theodore S. Hong, Selena S. Li, Jeffrey W. Clark, Christina L. Costantino, John T. Mullen, Samuel J. Klempner, Jennifer Y. Wo
Publikováno v:
Annals of Surgical Oncology. 28:2856-2865
Data are limited concerning the survival outcomes of locally advanced gastric cancer patients according to the multimodality therapy (MMT) administered. Single institution, retrospective analysis of 235 patients with locally advanced gastric cancer f