Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Elodie Modave"'
Autor:
Bruce A. Littlefield, Elodie Modave, Amy Weaver, Bram Boeckx, Diether Lambrechts, Agnieszka Wozniak, Patrick Schöffski
Publikováno v:
Clinical Cancer Research. 27:3106-3115
Purpose:A randomized phase III study evaluated the efficacy of eribulin versus dacarbazine in patients with advanced liposarcoma and leiomyosarcoma. Improved overall survival (OS) led to approval of eribulin for liposarcoma, but not for leiomyosarcom
Autor:
Patrick Schöffski, Hans Gelderblom, Elodie Modave, Jean-Yves Blay, Judith V.M.G. Bovée, Che-Jui Lee, Diether Lambrechts, Jozef Sufliarsky, Agnieszka Wozniak, Tom van Wezel, Raf Sciot, Maria Debiec-Rychter, Bram Boeckx
Publikováno v:
Clinical Cancer Research, 27(24), 6737-6748. AMER ASSOC CANCER RESEARCH
Purpose: The European Organization for Research and Treatment of Cancer (EORTC) clinical phase II trial 90101 “CREATE” showed high antitumor activity of crizotinib, an inhibitor of anaplastic lymphoma kinase (ALK)/ROS1, in patients with advanced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::883fc9b638545a34589047cb951cd737
https://lirias.kuleuven.be/handle/123456789/681918
https://lirias.kuleuven.be/handle/123456789/681918
Autor:
Diether Lambrechts, Maria Debiec-Rychter, Bram Boeckx, Jean-Yves Blay, Patrick Schöffski, Agnieszka Wozniak, Elodie Modave, Silvia Stacchiotti, Piotr Rutkowski, Che-Jui Lee, Raf Sciot
Publikováno v:
Cancers, Vol 13, Iss 6057, p 6057 (2021)
Cancers
Cancers; Volume 13; Issue 23; Pages: 6057
Cancers
Cancers; Volume 13; Issue 23; Pages: 6057
Simple Summary Clear cell sarcoma (CCSA) is a rare subtype of soft tissue sarcoma characterized by EWSR1 rearrangement and subsequent MET upregulation. The European Organisation for Research and Treatment of Cancer 90101 phase II trial evaluated the
Autor:
Karen Beets, Isabelle Etienne, Lies De Groef, Tine Van Bergen, Lieve Moons, Bram Boeckx, Inge Van Hove, Elodie Modave, Tjing-Tjing Hu, Jean H.M. Feyen, Diether Lambrechts, Michaël Porcu
Publikováno v:
Diabetologia. 63:2235-2248
Diabetic retinopathy is a common complication of diabetes and a leading cause of visual impairment and blindness. Despite recent advances, our understanding of its pathophysiology remains incomplete. The aim of this study was to provide deeper insigh
Autor:
Matthias P. Ebert, Patrick Dicker, Livio Trusolino, Jochen H. M. Prehn, Adam Lafferty, Elodie Modave, Alice C. O’Farrell, Enzo Medico, Giorgia Migliardi, Niraj Khemka, Rodrigo Dienstmann, Evy Vanderheyden, Andrea Bertotti, Francesco Sassi, Claudio Isella, Eugenia R. Zanella, Diether Lambrechts, Guillem Argiles, Josep Tabernero, Manuela Salvucci, Annette T. Byrne, Johannes Betge, Luise Halang, Bram Boeckx, Andreas U. Lindner
Publikováno v:
Clin Cancer Res
Purpose: Regorafenib (REG) is approved for the treatment of metastatic colorectal cancer, but has modest survival benefit and associated toxicities. Robust predictive/early response biomarkers to aid patient stratification are outstanding. We have ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24bd59b844860eb48b47b1d2324f5576
https://zenodo.org/record/7798369
https://zenodo.org/record/7798369
Autor:
Elodie Modave, Sylvie Negrier, Sebastien Benzekry, Andreas Bikfalvi, Andrea Emanuelli, Maeva Dufies, Gilles Pagès, Alain Ravaud, Damien Ambrosetti, Jean-Christophe Bernhard, Lindsay S. Cooley, Raphael Pineau, Emeline J. Ribot, Justine Rudewicz, Marie-Alix Derieppe, Stéphanie Verbeke, Francesco Falciani, Macha Nikolski, Kim Clarke, Jean Marc Ferrero, Sylvain Miraux, Diether Lambrechts, Cecile Taing, Wilfried Souleyreau
Publikováno v:
SSRN Electronic Journal.
Renal cell carcinoma (RCC) still lacks prognostic and predictive biomarkers to monitor the disease and the response to therapy. The usual strategy in translational research is to start from human samples, to identify molecular markers and gene networ
Autor:
Michael Lloyd, R. Jay Mashl, Yvonne A. Evrard, Jeffrey A. Moscow, Jong Il Kim, Alana L. Welm, Michael A. Davies, Carol J. Bult, Jayamanna Wickramasinghe, Rania El Botty, Dennis A. Dean, Jessica Giordano, Anuj Srivastava, Sandra D. Scherer, Jacqueline Rosains, Christian Frech, Elisabetta Marangoni, Jeffrey H. Chuang, Ryan Jeon, Shunqiang Li, Matthew H. Bailey, Yun-Suhk Suh, Elodie Modave, Yuanxin Xi, Enzo Medico, Li Ding, Livio Trusolino, Adam Lafferty, Vito W. Rebecca, Han-Kwang Yang, Jing Wang, Annette T. Byrne, Xing Yi Woo, Alice C. O’Farrell, Claudio Isella, Li Chen, Brandi N. Davis-Dusenbery, James H. Doroshow, Sherri R. Davies, Diether Lambrechts, Jos Jonkers, Bingliang Fang, Charles Lee, Roebi de Bruijn, Violeta Serra, Jack A. Roth, Rajesh Patidar, Funda Meric-Bernstam, Petra ter Brugge, Andrew V. Kossenkov, Hyun-Soo Kim, Andrea Bertotti, Emilio Cortes-Sanchez, Chieh-Hsiang Yang, Ramaswamy Govindan, Francesco Galimi, Jelena Randjelovic, Zi-Ming Zhao, Bryan E. Welm, Hua Sun, Meenhard Herlyn, Michael T. Lewis
Publikováno v:
Nature Genetics
Patient-derived xenografts (PDXs) are resected human tumors engrafted into mice for preclinical studies and therapeutic testing. It has been proposed that the mouse host affects tumor evolution during PDX engraftment and propagation, affecting the ac
Autor:
Bram Boecks, Bruce A. Littlefield, Amy Weaver, Elodie Modave, Patrick Schöffski, Agnieszka Wozniak, Diether Lambrechts
Publikováno v:
Cancer Research. 80:4280-4280
Background. The recent randomized phase 3 trial Eisai Study 309 evaluated efficacy of eribulin (ERI) compared to dacarbazine (DTIC) in advanced liposarcoma (LPS) and leiomyosarcoma (LMS). Improved overall survival (OS) in ERI-treated patients led to
Autor:
Han-Kwang Yang, Shunqiang Li, Jack A. Roth, Petra ter Brugge, Adam Lafferty, Elodie Modave, Bingliang Fang, Michael Lloyd, Anuj Srivastava, Annette T. Byrne, Michael A. Davies, Jos Jonkers, Violeta Serra, Diether Lambrechts, Brandi N. Davis-Dusenbery, Jeffrey H. Chuang, Funda Meric-Bernstam, Charles Lee, Carol J. Bult, Alice C. O’Farrell, Yvonne A. Evrard, Jeffrey A. Moscow, Yun-Suhk Suh, Li Ding, Livio Trusolino, Enzo Medico, Xing Yi Woo, Jong Il Kim, Alana L. Welm, Elisabetta Marangoni, Ramaswamy Govindan, Rania El Botty, Francesco Galimi, Andrea Bertotti, James Doroshow, Zi-Ming Zhao, Dennis A. Dean, Jessica Giordano, Bryan E. Welm, Claudio Isella, Meenhard Herlyn, Michael T. Lewis, Roebi de Bruijn
Publikováno v:
Cancer Research. 80:1118-1118
Patient-Derived Xenografts (PDXs) are preclinical models largely used to study tumor biology and drug response. Recent literature highlighted the possibility that growth of human tumors in a mouse microenvironment imposes a selection driving mouse-sp