Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Cunte Chen"'
TNFAIP3 mutation may be associated with favorable overall survival for patients with T-cell lymphoma
Autor:
Lihua Zhu, Cunte Chen, Sichu Liu, Lingling Zhou, Chengwu Zeng, Gengxin Luo, Wenyu Li, Ling Huang, Zheng Chen, Yangqiu Li
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-10 (2021)
Cancer Cell International
Cancer Cell International
Background T-cell lymphoma (TCL) is highly aggressive and has a poor prognosis; thus, it is worth exploring biomarkers that may predict clinical outcomes and investigate their potential role in developing targeted therapies. In this study, we charact
Autor:
Guixuan Huang, Zhi Yu, Yangqiu Li, Yumiao Li, Bo Li, Yuping Zhang, Jing Lai, Ming Zhou, Cunte Chen, Guangxiao Tan, Xiaolei Wei, Weifeng Luo, Qi Shen, Xiaohui Chen
Publikováno v:
Immunological Investigations. 50:406-415
Aplastic anemia (AA) is a T cell immune-mediated autoimmune disease. Overactivated CD8+ T cells play a leading role in the pathogenesis of AA, which may be due to disbalance in costimulatory and coinhibitory signals in T cells. In this study, we firs
Autor:
Haibo Mao, Qiong-Yao Liu, Pei-Pei Wang, Lin Lv, Yong Wu, Xiao-Fei Cao, Lina Wang, Si-Hong Liu, Guolong Liu, Dan Li, Shu-Xiang Zheng, Xisheng Fang, Xiao-Jun Chen, Cunte Chen, Baoxiu Li, Xia Liu, Shao-Li Luo, Chengyin Weng
Publikováno v:
International Journal of Biological Sciences
Lymphoma is a malignant disease of the hematopoietic system that typically affects B cells. The up-regulation of miR-148b is associated with radiosensitization in B-cell lymphoma (BCL). This study aimed to explore the role of miR-148b in regulating t
Autor:
Zhuandi Liu, Yixin Zeng, Zheng Chen, Yangqiu Li, Xibao Yu, Kehan Li, Chengwu Zeng, Ardalan Mansouri, Shaohua Chen, Rili Gao, Youxue Huang, Yuhong Lu, Cunte Chen
Publikováno v:
Clinical and Translational Medicine
Clinical and Translational Medicine, Vol 11, Iss 5, Pp n/a-n/a (2021)
Clinical and Translational Medicine, Vol 11, Iss 5, Pp n/a-n/a (2021)
Autor:
Zheng Chen, Yangqiu Li, Cunte Chen, Rili Gao, Youxue Huang, Xin Huang, Zhuandi Liu, Chengwu Zeng, Xibao Yu, Shaohua Chen, Kehan Li, Gengxin Luo, Grzegorz K. Przybylski
Publikováno v:
Biomarker Research
Biomarker Research, Vol 9, Iss 1, Pp 1-4 (2021)
Biomarker Research, Vol 9, Iss 1, Pp 1-4 (2021)
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive subtype of leukemia with poor prognosis, and biomarkers and novel therapeutic targets are urgently needed for this disease. Our previous studies have found that inhibition of the B-cell leu
Autor:
Yangqiu Li, Xiaojun Wei, Feili Chen, Cunte Chen, Hanguo Guo, Ling Huang, Wenyu Li, Sichu Liu, Xinmiao Jiang, Yang Shao
Publikováno v:
Experimental Hematology & Oncology
Experimental Hematology & Oncology, Vol 10, Iss 1, Pp 1-11 (2021)
Experimental Hematology & Oncology, Vol 10, Iss 1, Pp 1-11 (2021)
Background Tumor mutation burden (TMB) as estimated by cancer gene panels (CGPs) has been confirmed to be associated with prognosis and is effective in predicting clinical benefit from immune checkpoint blockade (ICB) in solid tumors. However, whethe
Autor:
Cunte Chen, Ling Xu, Rili Gao, Shunqing Wang, Yuping Zhang, Caixia Wang, Chengwu Zeng, Yangqiu Li
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 11 (2021)
Frontiers in Pharmacology, Vol 11 (2021)
Positive response to PD-1/PD-L1 blockades was observed in the treatment of solid tumors. However, the clinical response to PD-1/PD-L1 blockade varied in patients with acute myeloid leukemia (AML). It is thought that there are factors other than PD-1
Autor:
Zhou Ming, Guangxiao Tan, Li Bo, Weifeng Luo, Xiaohui Chen, Yu Zhi, Chen Lin, Qi Shen, Zhang Yuping, Lixing Guo, Guixuan Huang, Cunte Chen, Xiao Yankai, Li Yumiao
Publikováno v:
Blood Science, Vol 2, Iss 3, Pp 100-105 (2020)
Aberrant T cell activation is a major cause of aplastic anemia (AA) pathogenesis. Recent studies have shown that miRNAs regulate T cell activation and are involved in AA. A previous study found that miR-214 was significantly up-regulated upon T cell
Autor:
Caixia Wang, Cunte Chen, Shunqing Wang, Chi Leong Chio, Chaofeng Liang, Chengwu Zeng, Yuping Zhang, Yangqiu Li, Shaohua Chen
Publikováno v:
Journal of Hematology & Oncology
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-5 (2020)
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-5 (2020)
Immunotherapy with immune checkpoint inhibitors (ICIs) for solid tumors had significantly improved overall survival. This type of therapy is still not available for acute myeloid leukemia (AML). One major issue is the lack of knowledge for the expres
Autor:
Xiao-Wei Chen, Wenjian Mo, Wei Zhou, Peipei Wang, Shunqing Wang, Caixia Wang, Ming Zhou, Yu-Ping Zhang, Cunte Chen, Tingfen Deng
Publikováno v:
Oncology Letters
The aim of the present study was to examine the expression and clinical significance of long non-coding RNA (lncRNA)-CCDC26 in patients with acute myeloid leukemia (AML), and to investigate the potential functions of CCDC26. The Gene Expression Omnib