Zobrazeno 1 - 10
of 1 828
pro vyhledávání: '"Bridges, A."'
Autor:
Jeffrey L. Curtis, Peter Mancuso, Benjamin Bouchard, Kanakadurga Singer, Dave Bridges, Christine M. Freeman, Anne M. Weitzel, Cameron Griffin
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Obesity impairs host defense against Klebsiella pneumoniae, but responsible mechanisms are incompletely understood. To determine the impact of diet-induced obesity on pulmonary host defense against K. pneumoniae, we fed 6-wk-old male C57BL/6j mice a
Autor:
Hildegard Dohmen, Hans-Georg Wirsching, Andreas von Deimling, Marco Stein, John G. Golfinos, Thomas Hielscher, Annika K. Wefers, Jens Schittenhelm, Fay E. A. Greenway, Areeba Patel, David T.W. Jones, Christian Mawrin, Chandra N. Sen, Elisabeth J. Rushing, Katrin Lamszus, Christine Jungk, Christina Blume, Anna S. Berghoff, Annekathrin Reinhardt, Jürgen Hench, Peter Baumgarten, Martin Sill, Till Acker, Daniel Schrimpf, Damian Stichel, Wolfgang Wick, David E. Reuss, Matija Snuderl, Miriam Ratliff, Marian Christoph Neidert, Michael Platten, Leslie R. Bridges, Sybren L. N. Maas, Abigail K. Suwala, Manfred Westphal, Stefan M. Pfister, Helin Dogan, Guido Reifenberger, Patrick N. Harter, Zane Jaunmuktane, Gerhard Jungwirth, Conor Grady, Severina Leu, Felix Sahm, Melanie Bewerunge-Hudler, Andreas Unterberg, Philipp Sievers, Nima Etminan, Michael Weller, Ralf Ketter, Jonathan Serrano, Matthias Preusser, Sebastian Brandner, Philipp Euskirchen, Christel Herold-Mende, Franz Ricklefs, Timothy L. Jones, Kenneth Aldape, Stephan Frank, Daniel Hänggi
Publikováno v:
Journal of Clinical Oncology. 39:3839-3852
PURPOSE Meningiomas are the most frequent primary intracranial tumors. Patient outcome varies widely from benign to highly aggressive, ultimately fatal courses. Reliable identification of risk of progression for individual patients is of pivotal impo
Publikováno v:
J Neurophysiol
Supraspinal signals play a significant role in compensatory responses to postural perturbations. Although the cortex is not necessary for basic postural tasks in intact animals, its role in responding to unexpected postural perturbations after spinal
Autor:
Stacey S. Cofield, Shaila Kamal, Joseph Huffstutter, Norma Mendoza, Theresa L. Ford, S. Louis Bridges, Allen Jankeel, William Shergy, Jeffrey R. Curtis, David Ridley, Kaleb Michaud, John Bassler, Atul Deodhar, Alan Kivitz, Sarah A.R. Siegel, Stephen Lindsey, Kevin L. Winthrop, Ted R. Mikuls, Ilhem Messaoudi
Publikováno v:
Annals of Internal Medicine. 174:1510-1518
Background The safety and effectiveness of live virus vaccines, such as the varicella-zoster vaccine, are unknown in patients with inflammatory diseases receiving immunomodulatory therapy such as tumor necrosis factor inhibitors (TNFis). Objective To
Autor:
Nara S. Higano, Xuefeng Cao, Christopher D. Kroenke, Alyssa Filuta, Xiaojie Wang, Jason C. Woods, Jinbang Guo, James P. Bridges
Publikováno v:
J Perinatol
OBJECTIVE: To demonstrate sensitivity of diffusion-weighted MRI (DW-MRI) to pulmonary cellular-space changes during normal in-utero development using fetal rhesus macaques, compared to histological biomarkers. STUDY DESIGN: In-vivo/ex-vivo DW-MRI was
Autor:
Khiara M. Bridges
Publikováno v:
American Journal of Law and Equality. 1:46-51
Publikováno v:
Thorax
COVID-19 has different clinical stages, and effective therapy depends on the location and extent of the infection. The purpose of this review is to provide a background for understanding the progression of the disease throughout the pulmonary epithel
Publikováno v:
Applied Neuropsychology: Child. 11:771-780
Many patients that experience a concussion have impairing symptoms that persist beyond typical recovery timeframes. Concussion symptoms often remit within a month, but persisting impairments are difficult to characterize and attribute to concussion g
Autor:
Sichen Chang, Jonathan W. Dickerson, Baker Logan A, Thomas M. Bridges, Craig W. Lindsley, Darren W. Engers, Aidong Qi, Jerri M. Rook, Aaron M. Bender, P. Jeffrey Conn, Katrina A. Bollinger, Colleen M. Niswender, Changho Han, Alice L. Rodriguez, Trever R Carter, Li Peng, Julie L. Engers, Jordan C. O’Neill, Matthew Spock, Katherine J. Watson
Publikováno v:
ACS Med Chem Lett
[Image: see text] Herein, we report the SAR leading to the discovery of VU6028418, a potent M(4) mAChR antagonist with high subtype-selectivity and attractive DMPK properties in vitro and in vivo across multiple species. VU6028418 was subsequently ev
Autor:
Jerri M. Rook, Aaron M. Bender, Colleen M. Niswender, Yuping Donsante, P. Jeffrey Conn, Hyekyung P. Cho, Li Peng, Julie L. Engers, Jonathan W. Dickerson, Thomas M. Bridges, Craig W. Lindsley, Ellen J. Hess, Sichen Chang, Aidong Qi, Weimin Peng, Mark S. Moehle, Jordan C. O’Neill, Daniel J. Foster, Alice L. Rodriguez, Zoey Bryant, Katherine J. Watson, Kaylee J. Stillwell
Publikováno v:
ACS Pharmacology & Translational Science. 4:1306-1321
Nonselective antagonists of muscarinic acetylcholine receptors (mAChRs) that broadly inhibit all five mAChR subtypes provide an efficacious treatment for some movement disorders, including Parkinson's disease and dystonia. Despite their efficacy in t