Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Asher Chanan-Khan"'
Autor:
Raphael Clynes, Asher Chanan-Khan, Victoria R. Alegria, Ricardo D. Parrondo, Chelsea M. Johnson, Aneel Paulus, David M. Menke, Liuyan Jiang, Vivek Roy, Sikander Ailawadhi, David Liebowitz
Publikováno v:
Leukemia & Lymphoma. 63:738-742
Waldenstrom macroglobulinemia (WM) is an indolent, IgM-producing lymphoproliferative disorder that represents 1–2% of all non-Hodgkin lymphomas (NHL) [1]. High-risk patients, as defined by the inte...
Autor:
Sagar Lonial, Afsaneh Abdolzade-Bavil, Asher Chanan-Khan, Markus Ruehle, Farima Barmaki-Rad, Nikhil C. Munshi, Suraj Chandwani, George Somlo, Kevin R. Kelly, Sundar Jagannath, Ashot Minasyan, Sumit Madan, Andrea Wartenberg-Demand, Eva Herrmann-Keiner, Todd M. Zimmerman, Leonard T. Heffner, Sikander Ailawadhi, Faiza Rharbaoui, Thomas Haeder, David S. Siegel, Kenneth C. Anderson
Publikováno v:
The Lancet Haematology. 8:e794-e807
Summary Background Indatuximab ravtansine (BT062) is an antibody-drug conjugate that binds to CD138 and synergistically enhances the antitumor activity of lenalidomide in preclinical models of multiple myeloma. This phase 1/2a study was done to deter
Autor:
Gita Thanarajasingam, Asher Chanan-Khan, Prashant Kapoor, Angela Dispenzieri, Ronald S. Go, Wilson I. Gonsalves, Eli Muchtar, Morie A. Gertz, Allison C. Rosenthal, Thomas M. Habermann, Rebecca L. King, Jithma P. Abeykoon, David J. Inwards, Francis K. Buadi, Patricia T. Greipp, Vivek Roy, Sikander Ailawadhi, Robert A. Kyle, Grzegorz S. Nowakowski, Craig B. Reeder, David Dingli, Carrie A. Thompson, Jonas Paludo, Jeremy T. Larsen, Stephen M. Ansell, Thomas E. Witzig, Saurabh Zanwar, Rong He, S V Rajkumar, Taimur Sher, Shaji Kumar, Martha Q. Lacy
Publikováno v:
American Journal of Hematology. 96:945-953
Comparative data guiding initial therapy for Waldenstrom macroglobulinemia (WM), an infrequently encountered non-Hodgkin lymphoma, are sparse. We evaluated three commonly used frontline regimens: rituximab-bendamustine (R-Benda); dexamethasone, ritux
Autor:
Mizba Baksh, Aneel Paulus, Meghna Ailawadhi, Vivek Roy, Navnita Dutta, Gerson Quintero, Asher Chanan-Khan, Chander Shekher Aggarwal, Vivek Kumar, Mays F Abdulazeez, Victoria R. Alegria, Sikander Ailawadhi, Taimur Sher
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 21:e449-e455
Despite significant improvements in multiple myeloma (MM) treatment modalities, patient mortality early in the course of disease has been identified as a persistent phenomenon with variable reported rates and causes. Trends in early mortality over ti
Autor:
Wilson I. Gonsalves, Sikander Ailawadhi, Craig B. Reeder, Rahma Warsame, Ricardo D. Parrondo, David Dingli, Taimur Sher, Victoria R. Alegria, Muhamad Alhaj Moustafa, Prashant Kapoor, Suzanne R. Hayman, Asher Chanan-Khan, Eli Muchtar, Vivek Roy
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 21:355-360
Autor:
Mohamed A. Kharfan-Dabaja, Sonikpreet Aulakh, Farah Yassine, Ernesto Ayala, Ambuj Kumar, Javier Pinilla-Ibarz, Julio C. Chavez, Tea Reljic, Asher Chanan-Khan
Publikováno v:
Hematology/Oncology and Stem Cell Therapy, Vol 14, Iss 1, Pp 33-40 (2021)
Background Richter syndrome (RS) represents an aggressive disease resulting from transformation of chronic lymphocytic leukemia (CLL) to diffuse large B-cell or Hodgkin lymphoma. In 80% of cases, RS is clonally related to CLL. New therapies like ibru
Autor:
Asher Chanan-Khan, Aneel Paulus, David O. Hodge, Taimur Sher, Mark A. Fiala, Meghna Ailawadhi, Vivek Roy, Chander Shekher Aggarwal, Prachi Jani, Mays F Abdulazeez, Salman Ahmed, Victoria R. Alegria, Sonikpreet Aulakh, Ryan D. Frank, Sikander Ailawadhi, Zahara Kanji
Publikováno v:
Annals of Hematology. 100:735-741
Plasma cell disorders including plasmacytomas and multiple myeloma (MM) are exquisitely radiosensitive, and thus, radiation therapy (XRT) is used effectively in their management. The role of XRT in the setting of novel MM therapeutics has not been ex
Autor:
Olga Samoilova, Marie Sarah Dilhuydy, Andre Goy, Monelle Tamegnon, Asher Chanan-Khan, Michael Hallek, Mariya Salman, Simon Rule, Kerri Nottage, Anthony R. Mato, Graeme Fraser, Natasha Schuier, Javier Loscertales, Steven Sun, Angela Howes, Sebastian Grosicki, Ann Janssens, Miguel A. Pavlovsky, Sriram Balasubramanian, Fatih Demirkan, Abraham Avigdor, Rodrigo Santucci Silva, Nancy L. Bartlett, Jiri Mayer, Anne Connor, Paula Cramer
Publikováno v:
Leukemia & Lymphoma. 61:3188-3197
We report final analysis outcomes from the phase 3 HELIOS study (NCT01611090). Patients with relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma without deletion 17p (n = 578) were randomized 1:1 to 420 mg daily ibrutinib or p
Autor:
Mohamed A. Kharfan-Dabaja, Aneel Paulus, Chanel Wood, Prachi Jani, Rami Manochakian, Madiha Iqbal, Steven C. Ames, Aaron Spaulding, Shehzad K. Niazi, Salman Ahmed, Asher Chanan-Khan, Vivek Roy, Taimur Sher, Sikander Ailawadhi, Ernesto Ayala
Publikováno v:
Psychosomatics. 61:363-370
Hematopoietic cell recipients are reported to have a high prevalence of depression and anxiety. The impact of depression and anxiety on opioid use has not been well characterized. This is of significance as the opioid epidemic continues, and over 60%
Autor:
Asher Chanan-Khan, Aneel Paulus, Sharoon Akhtar, Harikrishna Reddy Rachamalla, Alak Manna, Raj Kumar Banerjee, Debabrata Mukhopadhyay, Vijay Sagar Madamsetty
Publikováno v:
Leukemia & Lymphoma. 61:2399-2408
Targeted drug delivery remains an active area of investigation in hematologic cancers. We have previously reported on a novel nanoparticle formulation (D1X) that can encapsulate drugs within a liposome whose lipid bilayer contains dexamethasone, whic