Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Amato F"'
Publikováno v:
Clinical Chemistry and Laboratory Medicine (CCLM). 58:1162-1164
There is a great debate regarding the usefulness and efficacy of this medication in anti-viral treatment: chloroquine is not included in the panel recommended for HIV treatment, while its modest effect in the therapy of human virus infection is repor
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 8562, p 8562 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 8562, p 8562 (2021)
The rare but dangerous adverse events evidenced after massive vaccination against SARS-CoV-2 are represented by thrombosis and thrombocytopenia. The patients diagnosed with severe COVID-19 may develop a pro-thrombotic state with a much higher frequen
Autor:
Michela Francalanci, Felice Amato, Giuseppe Castaldo, Carmela Colangelo, Giovanni Taccetti, Angelo Avarello, Vito Terlizzi, Eleonora Masi, Michele D'Andria, Donatello Salvatore, Giovanni Marsicovetere, Marika Comegna, Diletta Innocenti
Publikováno v:
Genes; Volume 12; Issue 8; Pages: 1178
Genes
Genes, Vol 12, Iss 1178, p 1178 (2021)
Genes
Genes, Vol 12, Iss 1178, p 1178 (2021)
We evaluated the effectiveness and safety of elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) in three subjects carrying the Phe508del/unknown CFTR genotype. An ex vivo analysis on nasal epithelial cells (NEC) indicated a significant improvement of CFT
Autor:
Antonella Miriam Di Lullo, Giuseppe Castaldo, Carmela Colangelo, Immacolata Zollo, Donatello Salvatore, Vito Terlizzi, Giovanni Taccetti, Marika Comegna, Felice Amato
Publikováno v:
Antibiotics
Antibiotics, Vol 10, Iss 828, p 828 (2021)
Volume 10
Issue 7
Antibiotics, Vol 10, Iss 828, p 828 (2021)
Volume 10
Issue 7
The new CFTR modulator combination, elexacaftor/tezacaftor/ivacaftor (Trikafta) was approved by the FDA in October 2019 for treatment of Cystic Fibrosis in patients 6 years of age or older who have at least one F508del mutation in one allele and a mi
Autor:
Vito Terlizzi, Giuseppe Castaldo, Felice Amato, Luis J. V. Galietta, Beatrice Ferrari, Giovanni Taccetti, Chiara Castellani
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 9, Iss 4, Pp n/a-n/a (2021)
Molecular Genetics & Genomic Medicine
Molecular Genetics & Genomic Medicine
Background New drugs that target the basic defect in cystic fibrosis (CF) patients may now be used in a large number of patients carrying responsive mutations. Nevertheless, further research is needed to extend the benefit of these treatments to pati
Autor:
Anna Procopio, Jolanda Sabatino, Ciro Indolfi, Christoph Liebetrau, Caterina Covello, Carlo Cosentino, Alessio Merola, Christian W. Hamm, Salvatore De Rosa, Francesco Amato, Alessia De Luca
Quantitative analysis of biochemical parameters is crucial for a correct diagnosis and prognosis of patients subject to acute myocardial infarction (AMI). In order to achieve a quantitative understanding of the dynamics of cardiac biomarkers, we have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92bfddc9e3e16f247b67c6c7463b7e8
http://hdl.handle.net/11577/3402715
http://hdl.handle.net/11577/3402715
Autor:
Stefano D'Errico, Giuseppe Castaldo, Andrea Patrizia Falanga, Felice Amato, Marika Comegna, Antonella Miriam Di Lullo, Gustavo Cernera, Giorgia Oliviero, Nicola Borbone, Maria Marzano, Gemma Conte, Francesca Ungaro, Ivana d'Angelo
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Cystic Fibrosis (CF) is characterized by an airway obstruction caused by a thick mucus due to a malfunctioning Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein. The sticky mucus restricts drugs in reaching target cells limiting the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1099113ee9769421360aaefc0849b731
http://hdl.handle.net/11588/848069
http://hdl.handle.net/11588/848069
Autor:
Monica Gelzo, Giuseppe Castaldo, Andrea Bianco, Federica Zarrilli, Lucio Pastore, Marika Comegna, Gustavo Cernera, Felice Amato, Filippo Scialò
Publikováno v:
Life
Life, Vol 11, Iss 94, p 94 (2021)
Life, Vol 11, Iss 94, p 94 (2021)
The defective mucociliary clearance due to CFTR malfunctioning causes predisposition to the colonization of pathogens responsible for the recurrent inflammation and rapid deterioration of lung function in patients with cystic fibrosis (CF). This has
Autor:
Vittorio Cerotto, Cecilia Becattini, Emanuela Falcinelli, Edoardo De Robertis, Haripriya KuchiBotla, Marco Malvestiti, Antonella Mencacci, Gaetano Vaudo, Teseo Lazzarini, Barbara Camilloni, Mariachiara Borghi, Elisa Piselli, Felice Amato, Giuseppe Castaldo, Loredana Bury, Eleonora Petito, Fabio Gori, Paolo Gresele, Ugo Paliani, Roberto Castronari
Publikováno v:
Platelets
The frequent finding of thrombocytopenia in patients with severe SARS-CoV-2 infection (COVID-19) and previous evidence that several viruses enter platelets suggest that SARS-CoV-2 might be internalized by platelets of COVID-19. Aim of our study was t
Autor:
Maria Gabriella Matera, Aurora Daniele, Andrea Bianco, Lucio Pastore, Filippo Scialò, Giuseppe Castaldo, Felice Amato, Mario Cazzola
Publikováno v:
Lung
Despite the unprecedented effort of the scientific community, the novel SARS-CoV-2 virus has infected more than 46 million people worldwide, killing over one million two hundred thousand. Understanding the mechanisms by which some individuals are mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5180e4616ec15eded34889dc9e10d9b6
http://hdl.handle.net/11588/839828
http://hdl.handle.net/11588/839828