Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alena Klochkova"'
Autor:
Charline Ogier, Elizabeth Handorf, Jaye C. Gardiner, Diana Restifo, Ralph Francescone, Janusz Franco-Barraza, Linara Gabitova, Emmanuelle Nicolas, Kathy Q. Cai, Battuya Bayarmagnai, Alena Klochkova, Aizhan Surumbayeva, Igor Astsaturov, Débora Barbosa Vendramini-Costa, Edna Cukierman
Publikováno v:
Cancer Research. 81:PR-015
Pancreatic ductal adenocarcinoma (PDAC) cells derive their resistance to therapy and aggressive clinical course from the symbiotic signaling and metabolic interactions with cancer-associated fibroblasts (CAFs). CAFs have been shown to provide to meta
Autor:
Anbin Mu, Dorian Frazier, Alena Klochkova, Mohammad Faujul Kabir, Adam Karami, Kelly A. Whelan, Andres J. Klein-Szanto
Publikováno v:
Gastroenterology. 160:S-264
Publikováno v:
Gastroenterology. 160:S-110
Cholesterol deprivation induces TGFβ signaling to promote basal differentiation in pancreatic cancer
Autor:
Diana Restifo, Alena Klochkova, Neelima Shah, Ido Sloma, Rachel Chiaverelli, Linara Gabitova, Suraj Peri, Richard A. Moffitt, Emmanuelle Nicolas, Alexandra Mazitova, Kathy Q. Cai, Tiffiney R. Hartman, Edna Cukierman, Erica A. Golemis, Alana M. O’Reilly, Elizabeth Handorf, Igor Astsaturov, Janusz Franco-Barraza, Ralph Francescone
SummaryOncogenic transformation alters the metabolism of cellular nutrients to sustain tumor growth. We here define a mechanism by which modifications in cholesterol metabolism control the formation of pancreatic ductal adenocarcinoma (PDAC). Disrupt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::501275a1cbf2e88f727507f1a817bde7
https://doi.org/10.1101/633719
https://doi.org/10.1101/633719
Autor:
Reshu Saxena, Caitlin Tice, Kishan Patel, Erika G. Karassik, Kelly A. Whelan, Henry P. Parkman, Julie Gang, Mary Grace Murray, Alena Klochkova, Timothy M. Hall, Marie Pier Tetreault, Sarah J. Ward, Daniel J. Farkas, Zachary Wilmer Reichenbach
Esophageal squamous cell carcinoma (ESCC) is among the most deadly forms of human malignancy characterized by late stage diagnosis, metastasis, therapy resistance and frequent recurrence. Clinical management of ESCC remains challenging and the diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72e2cf21d5a32911b014fe0923c63ffe
https://doi.org/10.1016/bs.acr.2019.05.004
https://doi.org/10.1016/bs.acr.2019.05.004
Autor:
Reshu Saxena, Mary Grace Murray, Tyler Beccari, Kelly A. Whelan, Julie Gang, Alena Klochkova, Andres J. Klein-Szanto, Amanda B. Muir, Mohammad Faujul Kabir
Publikováno v:
Gastroenterology. 158:S-185
Autor:
Edna Cukierman, Diana Restifo, Alena Klochkova, Linara Gabitova, Igor Astsaturov, Tiffiney R. Hartman, Aleksandra M. Mazitova
Publikováno v:
Cancer Research. 77:438-438
Pancreatic cancer is rapidly rising to become the 2nd leading cause of cancer deaths by 2020 in the USA. The rise in pancreatic cancer incidence is paralleled by the epidemic of obesity, type 2 diabetes, and associated increase in blood cholesterol,