Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Tarja Lamminen"'
Autor:
Kaiyang Zhang, Okan Gultekin, Elina A Pietilä, Jordi Gonzalez-Molina, Lidia Moyano-Galceran, Kaisa Lehti, Laura Lehtinen, Ulrika Joneborg, Tarja Lamminen, Sanaz Jamalzadeh, Johanna Hynninen, Tomás A Martins, Rainer Lehtonen, Sakari Hietanen, Sampsa Hautaniemi, Joseph W. Carlson, S. Pauliina Turunen, Seija Grénman, Olli Carpén, Katja Kaipio
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications
Nature Communications
Due to its dynamic nature, the evolution of cancer cell-extracellular matrix (ECM) crosstalk, critically affecting metastasis and treatment resistance, remains elusive. Our results show that platinum-chemotherapy itself enhances resistance by progres
Autor:
Jun Dai, Kaisa Huhtinen, Antti Häkkinen, Johanna Hynninen, Anna Vähärautio, Kaiyang Zhang, Olli Carpén, Katja Kaipio, Sampsa Hautaniemi, Sakari Hietanen, Jaana Oikkonen, Naziha Mansuri, Erdogan Pekcan Erkan, Tarja Lamminen, Noora Andersson
Chemotherapy resistance is the greatest contributor to cancer mortality and the most urgent unmet challenge in oncology. In order to reveal transcriptomics changes due to platinum-based chemotherapy we analyzed single-cell RNA-seq data from fresh tis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba6ea84cec7ea7d16b48d7c70b0f98ad
https://doi.org/10.1101/2020.06.06.138362
https://doi.org/10.1101/2020.06.06.138362
Autor:
Sakari Hietanen, Rainer Lehtonen, Laura Lehtinen, Pauliina S. Turunen, Olli Carpén, Johanna Hynninen, Jordi Gonzales-Molina, Antti Häkkinen, Tomas Santos Martins, Elina A Pietilä, Katja Kaipio, Kaisa Lehti, Tarja Lamminen, Kaiyang Zhang, Seija Grénman, Lidia Moyano-Galceran, Sanaz Jamalzadeh, Ville Rantanen, Sampsa Hautaniemi
Publikováno v:
Clinical Cancer Research. 26:A64-A64
Extracellular matrix (ECM) interactions contribute to cancer metastasis and chemotherapy resistance by regulating invasive cancer growth and apoptosis evasion. However, the key ECM pathways activated during cancer evolution, including tumor metastasi
Autor:
Amjad Alkodsi, Tarja Lamminen, Seija Grénman, Lasse Suominen, Jun Dai, Kaisa Huhtinen, Erdogan Pekcan Erkan, Katja Kaipio, Kaiyang Zhang, Anna Vähärautio, Olli Carpén, Naziha Mansuri, Johanna Hynninen, Sampsa Hautaniemi, Sakari Hietanen
Publikováno v:
Clinical Cancer Research. 26:A40-A40
Tumor heterogeneity in high-grade serous ovarian cancer (HGSOC) stems from highly variable copy number changes that lack shared actionable drug targets and contribute to inevitable recurrence and death. To unveil the vast heterogeneity in HGSOC, and