Zobrazeno 1 - 10
of 39
pro vyhledávání: '"William J, Calhoun"'
Autor:
Bill T. Ameredes, William J. Calhoun, Allan R. Brasier, Asanka S. Yapa, Obdulia Covarrubias-Zambrano, Madumali Kalubowilage, Christopher T. Culbertson, Hongwang Wang, Yingxin Zhao, Deryl L. Troyer, Massoud Motamedi, Aruni P. Malalasekera, Bing Tian, Stefan H. Bossmann
Publikováno v:
Nanomedicine
We report the design and adaptation of iron/iron oxide nanoparticle-based optical nanobiosensors for enzymes or cytokine/chemokines that are established biomarkers of lung diseases. These biomarkers comprise ADAM33, granzyme B, MMP-8, neutrophil elas
Publikováno v:
JAMA. 318(3)
Importance Asthma affects about 7.5% of the adult population. Evidence-based diagnosis, monitoring, and treatment can improve functioning and quality of life in adult patients with asthma. Observations Asthma is a heterogeneous clinical syndrome prim
Autor:
Konrad Pazdrak, Wendy I. White, Xuemei Luo, Susan Stafford, Alexander Kurosky, Zheng Wu, Kizhake V. Soman, John E. Wiktorowicz, William J. Calhoun
Publikováno v:
Journal of proteome research. 16(8)
Activated eosinophils contribute to airway dysfunction and tissue remodeling in asthma and thus are considered to be important factors in asthma pathology. We report here comparative proteomic and phosphoproteomic changes upon activation of eosinophi
Autor:
William J. Calhoun, Douglas Curran-Everett, Kian Fan Chung, Mario Castro, Elliot Israel, William W. Busse, Sally E. Wenzel, Wei Wu, Wendy C. Moore, Benjamin Gaston, Serpil C. Erzurum, Eugene R. Bleecker
Publikováno v:
Journal of Allergy and Clinical Immunology. 133:1280-1288
Background Previous studies have identified asthma phenotypes based on small numbers of clinical, physiologic, or inflammatory characteristics. However, no studies have used a wide range of variables using machine learning approaches. Objectives We s
Autor:
Jing Zhang, Maxim V. Ivannikov, Massoud Motamedi, Hong Sun, Bing Tian, Yingxin Zhao, Lata Kaphalia, Jia Zhou, Allan R. Brasier, William J. Calhoun, Zhiqing Liu, Rosario Maroto, Yueqing Zhang
Publikováno v:
J Proteomics
Small molecule inhibitors of the epigenetic regulator bromodomain-containing protein 4 (BRD4) are potential therapeutics for viral and allergen-induced airway remodeling. A limitation of their preclinical advancement is the lack of detailed understan
Publikováno v:
The Journal of Allergy and Clinical Immunology: In Practice. 3:594-596
Autor:
Benjamin Gaston, Wendy C. Moore, Elliot Israel, Stephen P. Peters, Craig M. Riley, Anne M. Fitzpatrick, Kian Fan Chung, Fernando Holguin, Nizar N. Jarjour, Mario Castro, William J. Calhoun, Eugene R. Bleecker, Ronald L. Sorkness, Sally E. Wenzel, Serpil C. Erzurum, William W. Busse, W. Gerald Teague
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 12, p e0145476 (2015)
PLoS ONE, Vol 10, Iss 12, p e0145476 (2015)
Introduction FEF25-75 is one of the standard results provided in spirometry reports; however, in adult asthmatics there is limited information on how this physiological measure relates to clinical or biological outcomes independently of the FEV1 or t
Autor:
William W. Busse, Mihaela Teodorescu, Kian Fan Chung, Mario Castro, William J. Calhoun, Patrick J. Strollo, Sally E. Wenzel, Elliot Israel, Serpil C. Erzurum, Eugene R. Bleecker, Faith S. Luyster
Publikováno v:
Sleep and Breathing. 16:1129-1137
The effect of sleep quality on asthma control independent from common comorbidities like gastroesophageal reflux disease (GERD) and obstructive sleep apnea (OSA) is unknown. This study examined the association between sleep quality and asthma control
Autor:
Shamsah Kazani, Eugene R. Bleecker, Douglas Curran-Everett, Thomas J. Mariani, Kian Fan Chung, Mario Castro, Gautham Marigowda, Nizar N. Jarjour, Sally E. Wenzel, Benjamin Gaston, Oliver Haworth, William J. Calhoun, William W. Busse, Bruce D. Levy, Elliot Israel, Serpil C. Erzurum, Anna Planaguma
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 178:574-582
Airway inflammation is common in severe asthma despite antiinflammatory therapy with corticosteroids. Lipoxin A(4) (LXA(4)) is an arachidonic acid-derived mediator that serves as an agonist for resolution of inflammation.Airway levels of LXA(4), as w
Autor:
Adante Hart, Samang Ung, Callan J. Burzynski, Susan Rappaport, Bennie McWilliams, Elizabeth Lancet, Sabrena Mervin-Blake, Michael O. Daines, Tara F. Carr, Jennifer Kustwin, David M. Shade, Nicholas Eberlein, Elise Pangborn, Connie Romaine, Ellen D. Brown, Patricia D. Rebolledo, Andre Rogatko, Anna Adler, Adam Wanner, Stephanie M. Burns, Jonathan Cruse, Deanna M. Green, Janette C. Priefert, Gail Weinmann, W. Gerald Teague, John Welter, Deborah Keaney Chassaing, Leonard B. Bacharier, Tonya Greene, Nienchun Wu, Daniel A. Searing, Edward T. Naureckas, Lilian Cadet, Jason E. Lang, Laura Bertrand, Weijiang Shen, Robert A. Wise, April Thurman, Janet Hutchins, Andrea Lears, Amber Martineau, John S. Sundy, Nancy Prusakowski, Christine A. Sorkness, Kaharu Sumino, Nina Phillips, Andreas Schmid, Flavia C.L. Hoyte, Silvia Lopez, Marie C. Sandi, Cristine E. Berry, Edward B. Mougey, Gwen Leatherman, Scott H. Sicherer, Lisa Monchil, Lucius Robinson, Dima Ezmigna, Gang Zheng, Paula J. Puntenney, Joan Reibman, V. Susan Robertson, Lisa Webber, Nicholas R. Anthonisen, Blanca A. Lopez, Michael F. Land, Kristina Rivera, Jessica Ghidorzi, Denise Thompson-Batt, Christian Bime, Brian P. Vickery, Xavier Soler, Marilyn Scharbach, Agnes Banquet, Johana Arana, Richard S. Tejedor, Suzanna Roettger, Jonathan P. Parsons, Ben Xu, Ankoor S. Shah, Denise Jaggers, Thomas Lahiri, Eliana S. Mendes, Lucy Wang, Eveline Y. Wu, David Cosmar, Gary I. Salzman, Elizabeth De La Riva-Velasco, Alicia Newcomer, John G. Mastronarde, Elizabeth A. Sugar, Razan Yasin, Mary A. Nevin, Fernando D. Martinez, Anne S Casper, Melissa M. Scheuerman, William J. Calhoun, Jesus A. Wences, James N. Moy, Virginia S. Taggart, Nicola A. Hanania, Anne E. Dixon, Asem Abdeljalil, William C. Bailey, Jessica Williams, Monroe J. King, Sarah M. Croker, Kenneth S. Knox, Mary Warde, Rubin I. Cohen, Sankaran Krishnan, Mario Castro, Newel Bryce-Robinson, Karen Carapetyan, Christine Y. Wei, Roni Grad, Stephen C. Lazarus, Nancy Busk, Patti Haney, Richard F. Lockey, Lewis J. Smith, Michael Campos, Jaime Tarsi, Wayne J. Morgan, James L. Goodwin, Norman H. Edelman, Charles G. Irvin, Noopur Singh, Janet T. Holbrook, Johnson Ukken, David A. Kaminsky, Ravi Kalhan, Kyle I. Happel, Joe Ramsdell, Mustafa A. Atik, Nancy Archer, Raymond G. Slavin, Maria Teresa Santiago, Paul Ferguson, Virginia Zagaja, Rachael A. Compton, Joseph Santiago, Katherine Chee, Brenda M. Patterson, Ramona Ramdeo, Monica T. Varela, Joseph Boyer, Allen J. Dozor, Catherine M Foss, Robert Smith, Michael Busk, Maureen Dreyfus, Marie Daniel, Sobharani Rayapudi, Shirley McCullough, Jenny Hixon, Stephen Wasserman, Holly Currier, Andrea Paco, Tara M. Formisano, Nadav Traeger, Ingrid Gherson, Thomas Matthews, Subhadra Siegel, Michelle Freemer, J.N. Saams, Rosemary Weese, Alexis L Rea, Y. Cathy Kim, Michelle M. Cloutier, Deborah Nowakowski, Kristin W. Wavell, Dennis Pyszczynski, Kathryn V. Blake, Peter J. Kahrilas, Marianna Sockrider, Rohit K. Katial, Mark A. Brown, Suzette T. Gjonaj, Zenobia Gonsalves, Arleen Antoine, Lynn B. Gerald, Emily DiMango, Linda Rogers, Debra Amend-Libercci, Abbi Brees, Deanna Seymour, Abid Bhat, John J. Lima, Stephanie Allen, Diana B. Lowenthal, Katie Kinninger, Rebecca McCrery, Janice Drake, Cori L. Daines, Charlene Levine, Elizabeth K. Fiorino, Monica M. Vasquez, Terri Montgomery, Donna Wolf, Trisha Larson
Publikováno v:
JAMA. 313(20)
Importance Soy isoflavone supplements are used to treat several chronic diseases, although the data supporting their use are limited. Some data suggest that supplementation with soy isoflavone may be an effective treatment for patients with poor asth