Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jon-Kar Zubieta"'
Autor:
Keith G Jones, Kendal A. Walker, Mike Angstadt, Margit Burmeister, Brian J. Mickey, David Goldman, Robert C. Welsh, Katherine G. Warthen, Chandra Sripada, Benjamin Sanford, Jon Kar Zubieta
Publikováno v:
Neuropsychopharmacology. 44:495-502
Neuropeptide Y (NPY) produces anxiolytic effects in rodent models, and naturally occurring low NPY expression in humans has been associated with negative emotional phenotypes. Studies in rodent models have also demonstrated that NPY elicits reward be
Autor:
Peter Scott, Robert A. Koeppe, Bradford D. Henderson, Alexandre F. DaSilva, Henry F. VanBrocklin, Jon Kar Zubieta, Brian G. Hockley, Joseph E. Blecha, Xia Shao, Michael R. Kilbourn
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 60:375-380
[11 C]Carfentanil ([11 C]CFN) is a selective radiotracer for in vivo positron emission tomography imaging studies of the μ-opioid system that, in our laboratories, is synthesized by methylation of the corresponding carboxylate precursor with [11 C]M
Autor:
Catherine Dion, Brian J. Mickey, Natania A. Crane, Scott A. Langenecker, Jon Kar Zubieta, Jennifer R. Gowins, Lisanne M. Jenkins, Runa Bhaumik
Publikováno v:
Brain. 140:472-486
Predicting treatment response for major depressive disorder can provide a tremendous benefit for our overstretched health care system by reducing number of treatments and time to remission, thereby decreasing morbidity. The present study used neural
Autor:
Shannon Powers, Brett Froeliger, Eric L. Garland, Patrick A. McConnell, Roger D. Newman-Norlund, Jon Kar Zubieta
Publikováno v:
Addict Biol
Preclinical studies have shown effects of chronic exposure to addictive drugs on glutamatergic-mediated neuroplasticity in frontostriatal circuitry. These initial findings have been paralleled by human functional magnetic resonance imaging (fMRI) res
Autor:
Peter Eichhammer, Brian J. Mickey, Kathleen H. Elverman, David T. Hsu, Susan E. Kennedy, Saulo M. Ribeiro, Margit Burmeister, Scott A. Langenecker, Tiffany M. Love, Mary M. Heitzeg, David Goldman, Stanley J. Watson, Robert A. Koeppe, Huda Akil, Srijan Sen, Jon Kar Zubieta
Publikováno v:
Frontiers in Psychology, Vol 10 (2019)
Frontiers in Psychology
Frontiers in Psychology
Heterogeneity within Major Depressive Disorder (MDD) has hampered identification of biological markers (e.g., intermediate phenotypes, IPs) that might increase risk for the disorder or reflect closer links to the genes underlying the disease process.
Publikováno v:
Pain Reports
PAIN Reports, Vol 4, Iss 4, p e769 (2019)
PAIN Reports, Vol 4, Iss 4, p e769 (2019)
The enormous advancements in the medical imaging methods witnessed in the past decades have allowed clinical researchers to study the function of the human brain in vivo, both in health and disease. In addition, a better understanding of brain respon
Autor:
Michelle T. Kassel, Monica N. Starkman, Linas A. Bieliauskas, Robert C. Welsh, Bruno Giordani, Scott A. Langenecker, Douglas C. Noll, Anne L. Weldon, Erich T. Avery, Laura B. Gabriel, Sara L. Weisenbach, Marta Peciña, Sara J. Walker, Julia A. Rao, Jon Kar Zubieta, Ciaran M. Considine, Emily M. Briceño, Brennan D. Haase
Publikováno v:
Journal of the International Neuropsychological Society. 22:412-425
Objectives: Individuals with major depressive disorder (MDD) demonstrate poorer learning and memory skills relative to never-depressed comparisons (NDC). Previous studies report decreased volume and disrupted function of frontal lobes and hippocampi
Autor:
Julia A. Rao, Jon Kar Zubieta, Erica A. Hymen, Scott A. Langenecker, Lisanne M. Jenkins, Sara L. Weisenbach, Maia Feigon
Publikováno v:
Journal of the International Neuropsychological Society. 22:225-239
Objectives: There is a well-known association between memory impairment and major depressive disorder (MDD). Additionally, recent studies are also showing resting-state functional magnetic resonance imaging (rsMRI) abnormalities in active and remitte
Autor:
Scott A. Langenecker, Olusola Ajilore, David T. Hsu, Marta Peciña, K. L. Phan, Jon Kar Zubieta, Alyssa Barba, Lisanne M. Jenkins, Kelly A. Ryan, Jennifer R. Gowins, Heide Klumpp, Rachel H. Jacobs, Brian J. Mickey, Robert C. Welsh, Magdalena Sikora
Publikováno v:
Psychological Medicine. 46:1055-1067
BackgroundRecent meta-analyses of resting-state networks in major depressive disorder (MDD) implicate network disruptions underlying cognitive and affective features of illness. Heterogeneity of findings to date may stem from the relative lack of dat
Autor:
Brian J. Mickey, Jon Kar Zubieta, Erich T. Avery, Magdalena Sikora, Joseph Heffernan, Marta Peciña
Publikováno v:
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 1:68-76
Background Recent neuroimaging studies have demonstrated resting-state functional connectivity (rsFC) abnormalities among intrinsic brain networks in major depressive disorder (MDD); however, their role as predictors of treatment response has not yet