Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Ye Zheng"'
Autor:
Ryan C. Gimple, Guoxin Zhang, Linjie Zhao, Leo J.Y. Kim, Jia Z. Shen, Cheryl Kim, Briana C. Prager, Xujun Wang, Jean A. Bernatchez, Xiang-Dong Fu, Jeremy N. Rich, Kailin Yang, Jair L. Siqueira-Neto, Deobrat Dixit, Zhixin Qiu, Lukas Chavez, Zhe Zhu, Deguan Lv, Ye Zheng, Denise Hinz, Zhengyu Liang, Charles Spruck, Xiuxing Wang, Chunyu Jin, Qiyuan Yang, Qiulian Wu, Lihua Min, Katherine A. Jones, Zhen Dong, Shruti Bhargava
Publikováno v:
Cancer Discov
Glioblastoma (GBM) is the most lethal primary brain cancer characterized by therapeutic resistance, which is promoted by GBM stem cells (GSC). Here, we interrogated gene expression and whole-genome CRISPR/Cas9 screening in a large panel of patient-de
Autor:
Zhe Li, Xirun Zheng, Zecheng Yu, Bin Wu, Xinmin Qiu, Mingbang Wang, Xiaodong Luo, Wai Sang Poon, Chunying Zheng, Xianwei Su, Zhuo Li, Yuzhen Fan, Weiwei Chen, Yan Zeng, Qiaodi Cai, Enli Luo, Jianwen Guo, Qiao-Zhen Su, Wai-Yee Chan, Chun-Ye Zheng, Yingjun Chen, Gang Lu, Yanjuan Xu, Xinjie Chen, Zhangyong Xia
Publikováno v:
Neuroscience. 480:65-78
Parkinson's disease (PD) is the second most frequently diagnosed neurodegenerative disease. The purpose of this study was to investigate the link between microbiota composition in important mucosal interfaces (oral, nasal, and intestinal) and PD. Seq
Autor:
Alexandre V. Hirayama, Raphael Gottardo, Delaney R. Kirchmeier, Mark R. Dowling, Jordan Gauthier, David G. Maloney, Ye Zheng, Alyssa Sheih, Cameron J. Turtle, Abby W. Chucka, Tinh-Doan Phi
Publikováno v:
Blood. 138:1749-1749
Introduction Lymphodepletion chemotherapy followed by infusion of autologous T cells engineered to express a CD19-targeted chimeric antigen receptor (CAR) has shown high response rates in relapsed or refractory high-risk chronic lymphocytic leukemia
Autor:
Michael A. Fischbach, Ye Zheng, Lina Yao, Jun R. Huh, Fraydoon Rastinejad, A. Sloan Devlin, Samantha P. Kelly, Dan R. Littman, Jingping Lu, Randy S. Longman, Saiyu Hang, Eunha Kim, Soyoung Ha, Donggi Paik, Michael R. Krout, Brandon N. Nelson, Jamma Trinath, Lin Wu
Bile acids are abundant in the mammalian gut, where they undergo bacteria-mediated transformation to generate a large pool of bioactive molecules. Although bile acids are known to affect host metabolism, cancer progression and innate immunity, it is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e6ca6e8892e89ae36b99e90f5f6de3
https://doi.org/10.1038/s41586-019-1785-z
https://doi.org/10.1038/s41586-019-1785-z
Autor:
Jovylyn Gatchalian, Chin-San Loo, Bhargav Venkatraghavan, Yuqiong Liang, Josephine Ho, Ye Zheng, Diana C. Hargreaves, Mingjun Xie, Mathias Leblanc
Publikováno v:
Immunity
Summary Regulatory T (Treg) cells play a pivotal role in suppressing auto-reactive T cells and maintaining immune homeostasis. Treg cell development and function are dependent on the transcription factor Foxp3. Here, we performed a genome-wide CRISPR
Autor:
Xiaohui Zhou, Ye Zheng, Zhanqing Zhang, Wei Lu, Danping Liu, Min Wu, Jiahui Ding, Zhenghong Yuan, Yanling Feng, Mingzhu Xu, Xiaonan Zhang
Chronic Hepatitis B Virus (HBV) infection is strongly associated with the progression of liver fibrosis, cirrhosis and hepatocellular carcinoma. Despite intensive study, the detailed mechanisms leading to HBV induced liver disease have not been fully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69cf17aa0743749aef2c54d5ab8fa61
https://doi.org/10.1101/2020.01.13.904201
https://doi.org/10.1101/2020.01.13.904201
Autor:
Chun-Ye Zheng, Hong-Feng Liang, Xiao-Dong Luo, Ai-Ping Gu, Qiao-Zhen Su, Jun Cai, Xin-Chun Zhang, Hua-Jun Wang
Publikováno v:
Biochemical and Biophysical Research Communications. 502:269-275
Neuroinflammation plays a critical role in the process of neurodegenerative disorders, during which microglia, the principal resident immune cells in the central nervous system, are activated and produce proinflammatory mediators. Yin-Yang 1 (YY1), a
Autor:
Kelly A. Remedios, Mark H. Ginsberg, Jane E. Klann, Justine Lopez, Brian G. Petrich, Lauren A. Mack, John T. Chang, Stephanie H. Kim, Ye Zheng, Patrick J. Metz
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950), vol 198, iss 12
Talin, a cytoskeletal protein essential in mediating integrin activation, has been previously shown to be involved in the regulation of T cell proliferation and function. In this study, we describe a role for talin in maintaining the homeostasis and
Publikováno v:
Current Protocols in Immunology. 126
Adipose tissue (AT) serves a crucial role in maintaining organismal metabolic homeostasis. Studies have demonstrated that AT is populated with a diverse array of immune cells that coordinate and regulate AT function. This adipo-immune system is highl
Autor:
S. Jeson Sangaralingham, Gerald E. Harders, Shuchong Pan, Ye Zheng, John C. Burnett, Yang Chen, Seethalakshmi R. Iyer, Tomoko Ichiki, Horng H. Chen
Publikováno v:
J Mol Cell Cardiol
The native particulate guanylyl cyclase B receptor (pGC-B) activator, C-type natriuretic peptide (CNP), induces anti-remodeling actions in the heart and kidney through the generation of the second messenger 3', 5' cyclic guanosine monophosphate (cGMP