Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Xianjin Zhu"'
Publikováno v:
Cancer Science
Although the targeted tyrosine kinase inhibitor imatinib mesylate (IM) has achieved significant responses against CML in the clinical setting, a small proportion of patients fail to respond to IM treatment and their disease continues to progress, ind
Autor:
Xianjin Zhu, Hui Xu, Ting Gu, Gang Ma, Xiangdong Chen, Ningli Li, Jie Zhang, Baihua Shen, Pinru Wu, Beiqing Wang, Yue Sun, Rongfen Huo
Publikováno v:
Clinical Immunology. 174:53-62
Purpose Interleukin-8 (IL-8) is an important factor in the pathogenesis of psoriasis vulgaris, which is characterized by proliferation of keratinocytes, neutrophil infiltration and angiogenesis. Cysteine-rich 61 (Cyr61/CCN1), a secreted extracellular
Autor:
Taisen Hao, Yingping Cao, Pingxia Lu, Xianjin Zhu, Chenqing Zhang, Yanfang Song, Jianda Hu, Zhen Lin, Conglian Wu, Yanli Kang, Qinghua Huang
Publikováno v:
International journal of molecular medicine. 43(2)
Elevated Cyr61 levels have been reported in various malignancies. Elevation of Cyr61 protein levels contributes to the proliferation, metastasis, and chemotherapy resistance of malignant cells. Previously, it was discovered that Cyr61 is elevated in
Autor:
Yanfang Song, Xiaoxuan Sun, Yong He, Baihua Shen, Lianbo Xiao, Yue Sun, Zhou Zhou, Songtao Sun, Tianhang Zhai, Ningli Li, Hua-Li Gao, Jie Zhang, Rongfen Huo, Xianjin Zhu, Huidan Li, Miaojia Zhang
Publikováno v:
Clinical Immunology. 157:187-197
IL-1β plays a major role in the development of rheumatoid arthritis (RA). We previously showed that Cyr61 participates in RA pathogenesis as a proinflammatory factor. Here, we found that the levels of IL-1β and Cyr61 were higher in RA SF than in os
Autor:
Xianjin Zhu, Rongfen Huo, Jinpiao Lin, Tianhang Zhai, Zhou Zhou, Pinru Wu, Huidan Li, Yue Sun, Baihua Shen, Jie Zhang, Ningli Li
Publikováno v:
Journal of Ethnopharmacology. 158:283-290
Ethnopharmacological relevance Tripterygium preparations (TPs), a traditional Chinese Medicines extracted from Tripterygium wilfordii Hook f., are widely used for treatment of rheumatoid arthritis (RA). However, TPs from different Pharmaceutical fact
Autor:
Conglian Wu, Xianjin Zhu, Yingping Cao, Pingxia Lu, Yanfang Song, Ningli Li, Meihua Wang, Chenqing Zhang, Yulin Lin, Chuxi Pan, Wanting Li, Rongfen Huo, Peizheng Zheng
Publikováno v:
Scientific Reports
Cyr61 (CCN1) is the product of a growth factor–inducible immediate early gene and is involved in cell adhesion, survival, proliferation and differentiation. Cyr61 is overexpressed in human tumors and is involved in the development of tumors. Howeve
Autor:
Xianjin Zhu, Yue Sun, Jie Zhang, Rongfen Huo, Baihua Shen, Songtao Sun, Yong He, Ningli Li, Jun Xie, Jinpiao Lin, Zhou Zhou, Xiao Lianbo
Publikováno v:
Arthritis Research & Therapy
Introduction It is well known that neutrophils play very important roles in the development of rheumatoid arthritis (RA) and interleukin (IL)-8 is a critical chemokine in promoting neutrophil migration. We previously showed that increased production