Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Robert J. Tower"'
Autor:
Claus C. Glüer, Susanne Sebens, Eva Peschke, Kerstin Lüdtke-Buzug, Tuula Peñate Medina, Jan-Bernd Hövener, Holger Kalthoff, Kalevi Kairemo, Arndt Rohwedder, Susann Boretius, Charlotte Hauser, Oula Peñate Medina, Olga Will, Lia Appold, Marcus Bötcher, Qi Ling, Robert J. Tower, Lukas Huber, Carola Heneweer, Rolf Mentlein, Fatma Ashkenani
Publikováno v:
Current Pharmaceutical Design. 28:313-323
Background: Pancreatic ductal adenocarcinoma (PDAC), which ranks forth on the cancer-related death statistics still is both a diagnostic and a therapeutic challenge. Adenocarcinoma of the exocrine human pancreas originates in most instances from mali
Autor:
Lutian Yao, Snehal S. Shetye, Yulong Wei, Yejia Zhang, Robert J. Tower, Robert L. Mauck, Sarah E. Gullbrand, Zuozhen Tian, Ling Qin
Publikováno v:
Am J Phys Med Rehabil
OBJECTIVE The aim was to identify the source of cells within the center of the abnormal fibrocartilage tissue of the degenerative intervertebral disc after injury. DESIGN Cross-breeding of mice with an inducible type II promoter collagen construct (C
Autor:
Lutian Yao, Danielle Rux, Ling Qin, Marco Angelozzi, Ranjan Kc, Renata Pellegrino da Silva, Abdul Haseeb, Véronique Lefebvre, Robert J. Tower, Maurizio Pacifici, Charles de Charleroy
Publikováno v:
Yearbook of Paediatric Endocrinology.
Cartilage is essential throughout vertebrate life. It starts developing in embryos when osteochondroprogenitor cells commit to chondrogenesis, activate a pancartilaginous program to form cartilaginous skeletal primordia, and also embrace a growth-pla
Autor:
Takashi Sono, Zhu Li, Jing Xu, Qizhi Qin, Robert J. Tower, Thomas L. Clemens, Aaron W. James, Carolyn A. Meyers, Amy Lu, Stefano Negri, Yuefan Wang, Edward F. McCarthy
Bone regeneration following injury is initiated by inflammatory signals and occurs in association with infiltration by sensory nerve fibers. Together, these events are believed to coordinate angiogenesis and tissue reprogramming, but the mechanism of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21060f7c035740e45aa189a12d1dc60f
https://doi.org/10.1101/2021.07.07.451468
https://doi.org/10.1101/2021.07.07.451468
Autor:
Motomi Enomoto-Iwamoto, Haoruo Jia, Luqiang Wang, Ling Qin, Sun H, Maurizio Pacifici, Eiki Koyama, Wei Tong, Robert J. Tower, Leilei Zhong, Chider Chen, Yulong Wei, Gaoyuan Cao
Publikováno v:
Stem Cells
Long bone development involves the embryonic formation of a primary ossification center (POC) in the incipient diaphysis followed by postnatal development of a secondary ossification center (SOC) at each epiphysis. Studies have elucidated major basic
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 315:E446-E453
Cyclic GMP (cGMP) is an important intracellular regulator of endochondral bone growth and skeletal remodeling. Tadalafil, an inhibitor of the phosphodiesterase (PDE) type 5 (PDE5) that specifically hydrolyzes cGMP, is increasingly used to treat child
Autor:
Stefano Negri, Cedric R Uytingco, Zhu Li, Aaron W. James, Yu Hao Cheng, Robert J. Tower, Feng Quan Zhou, Thomas L. Clemens, Qian Zhang, Patrick Cahan, Xue-Wei Wang, Arun Venkatesan, Labchan Rajbhandari
Publikováno v:
Proc Natl Acad Sci U S A
The patterning and ossification of the mammalian skeleton requires the coordinated actions of both intrinsic bone morphogens and extrinsic neurovascular signals, which function in a temporal and spatial fashion to control mesenchymal progenitor cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dac764abe893f52cbb85c9d352bfeeb
http://hdl.handle.net/11562/1062218
http://hdl.handle.net/11562/1062218
Autor:
Jody E. Hooper, Leititia Zhang, Yongxing Gao, Leslie Chang, Sridhar Nimmagadda, Yiyun Wang, Aaron W. James, Jiajia Xu, Carol D. Morris, Dongqing Li, Ching Yun Hsu, Kristen P. Broderick, Carolyn A. Meyers, Ye Tian, Bruno Péault, Robert J. Tower
Publikováno v:
Bone Research
Bone Research, Vol 8, Iss 1, Pp 1-14 (2020)
Bone Research, Vol 8, Iss 1, Pp 1-14 (2020)
Human osteogenic progenitors are not precisely defined, being primarily studied as heterogeneous multipotent cell populations and termed mesenchymal stem cells (MSCs). Notably, select human pericytes can develop into bone-forming osteoblasts. Here, w
Autor:
Yulong Wei, Luqiang Wang, Jihwan Park, Yanqing Gong, Mingyao Li, Robert J. Tower, Leilei Zhong, Fanxin Long, Katalin Susztak, Nathanial Dyment, Chider Chen, Wei Tong, Patrick Seale, Nicholas Holdreith, Wei Yu, Zhen Miao, Ling Qin, Xiaobin Huang, Yejia Zhang, Lutian Yao, Jaimo Ahn, Rojesh Shrestha
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Bone marrow mesenchymal lineage cells are a heterogeneous cell population involved in bone homeostasis and diseases such as osteoporosis. While it is long postulated that they originate from mesenchymal stem cells, the true identity of progenitors an
Autor:
Robert J. Tower, Leilei Zhong, Luqiang Wang, Jihwan Park, Patrick Seale, Yulong Wei, Chider Chen, Nathanial Dyment, Fanxin Long, Wei Tong, Xiaobin Huang, Ling Qin, Zhen Miao, Lutian Yao, Rojesh Shrestha, Wei Yu, Yanqing Gong, Jaimo Ahn, Yejia Zhang, Mingyao Li, Katalin Susztak, Nicholas Holdreith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc5af1702452c205c8c4a2c0979c2b72
https://doi.org/10.7554/elife.54695.sa2
https://doi.org/10.7554/elife.54695.sa2