Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Reinaldo N. Takahashi"'
Autor:
Cristina A.J. Stern, Cristiane Ribeiro de Carvalho, Leandro J. Bertoglio, Reinaldo N. Takahashi
Publikováno v:
Neuroscience. 370:62-80
Posttraumatic stress and drug use disorders may stem from aberrant memory formation. As the endocannabinoid (eCB) system has a pivotal role in emotional memory processing and related synaptic plasticity, here we seek to review and discuss accumulatin
Autor:
Valentina Cinquina, Cristina Lemos, Attila Köfalvi, Bárbara S. Pinheiro, Rodrigo A. Cunha, Catherine Ledent, Samira G. Ferreira, Reinaldo N. Takahashi, Alán Alpár, Rafael Mariano de Bitencourt, Tibor Harkany, Gert Lubec, Fernando J. Sialana
Publikováno v:
Neurochemistry International. 90:72-84
Corticosteroid and endocannabinoid actions converge on prefrontocortical circuits associated with neuropsychiatric illnesses. Corticosteroids can also modulate forebrain synapses by using endocannabinoid effector systems. Here, we determined whether
Autor:
Rafael Mariano de Bitencourt, Juliana A.V. Kroon, Rimenez R. Souza, Fabricio Hoffmann Martins Do Monte, Reinaldo N. Takahashi
Publikováno v:
Behavioural Brain Research. 250:23-27
Previous studies have implicated cannabinoids in extinction of conditioned fear. We have recently showed that intraventricular infusion of the phytocannabinoid cannabidiol (CBD) facilitates fear extinction, but the brain regions underlying this effec
Publikováno v:
Neuroscience letters. 622
Understanding the mechanisms responsible for nonmotor manifestations of Parkinson's disease (PD) is crucial in the search for new therapeutic approaches. The aim of the present study was to evaluate the time course of behavioral, neurochemical, and m
Autor:
P. Mormède, Leandro F. Vendruscolo, E. Terenina, J. C. M. Vendruscolo, André Ramos, Reinaldo N. Takahashi
Publikováno v:
Genes, Brain and Behavior
Genes, Brain and Behavior, Wiley, 2009, 8 (3), pp.267-274. ⟨10.1111/j.1601-183X.2008.00465.x⟩
Genes, Brain and Behavior, Wiley, 2009, 8 (3), pp.267-274. ⟨10.1111/j.1601-183X.2008.00465.x⟩
Chantier qualité GA; International audience; This study investigated genetic influences on behavioral and neuroendocrine responses to cocaine sensitization. We used male and female rats of the inbred strains Lewis (LEW) and spontaneously hypertensiv
Autor:
Jorge Camilo Flório, Rui Daniel Prediger, Reinaldo N. Takahashi, Pablo Pandolfo, Luciano C. Batista, Rodrigo Medeiros
Publikováno v:
Experimental Neurology. 202:391-403
Many studies have shown that deficits in olfactory and cognitive functions precede the classical motor symptoms seen in Parkinson's disease (PD) and that olfactory testing may contribute to the early diagnosis of this disorder. Although the primary c
Autor:
Janaina C. M. Vendruscolo, Reinaldo N. Takahashi, Pierre Mormède, Leandro F. Vendruscolo, André Ramos, Elena Terenina-Rigaldie, Frantz Raba
Publikováno v:
Neuroscience Letters
Neuroscience Letters, Elsevier, 2006, 409 (2), pp.89-94. ⟨10.1016/j.neulet.2006.07.026⟩
Neuroscience Letters, Elsevier, 2006, 409 (2), pp.89-94. ⟨10.1016/j.neulet.2006.07.026⟩
The exposure of animals to a variety of stressful events can induce behavioral and physiological responses, which can be modulated by anxiety levels. It is well recognized that genetic factors play a substantial role in both anxiety and stress reacti
Autor:
Alcir Luiz Dafre, Reinaldo N. Takahashi, Patricia S. Brocardo, Ana Lúcia S. Rodrigues, Pablo Pandolfo
Publikováno v:
Toxicology. 207:283-291
This study investigates the effects of acute exposure to organophosphate insecticide malathion (250 mg/kg, i.p.) and/or ZnCl2 (5 mg/kg, i.p.), with the following parameters: lipid peroxidation and the activity of acetylcholinesterase (AChE), glutathi
Autor:
Daniel Rial, Rui Daniel Prediger, Cláudia P. Figueiredo, Rodrigo Medeiros, Richard L. Doty, Reinaldo N. Takahashi
Publikováno v:
Annals of the New York Academy of Sciences. 1170
The presence of smell loss and the early pathological involvement of the olfactory pathways in the early stages of some neurodegenerative disorders are in accord with the tenants of the olfactory vector hypothesis. This hypothesis postulates that som
Autor:
Rafael Trevisan, Jeferson Luis Franco, Alcir Luiz Dafre, Reinaldo N. Takahashi, Pablo Pandolfo, Ana Lúcia S. Rodrigues, Marcelo Farina, Patricia S. Brocardo, Marcela Uliano-Silva, Adair R.S. Santos
Publikováno v:
Basicclinical pharmacologytoxicology. 102(4)
The wide use of the organophosphate insecticide malathion is accompanied by the risk of human exposure, especially in developing countries, which underlines the need of basic studies in this area. Some reports have shown that low doses of malathion,