Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Patricia Sancho"'
Autor:
Eva Crosas-Molist, Aránzazu Sánchez, Joan Fernando, Margarita Fernández, Judit López-Luque, Patricia Sancho, Esther Bertran, Estanis Navarro, Isabel Fabregat
Publikováno v:
Free Radical Biology and Medicine. 69:338-347
The NADPH oxidase NOX4 has emerged as an important source of reactive oxygen species in signal transduction, playing roles in physiological and pathological processes. NOX4 mediates transforming growth factor-β-induced intracellular signals that pro
Autor:
Marta Cañamero, Maria M. Azevedo, Bruno Sainz, Sonia Alcalá, Patrick C. Hermann, Mert Erkan, Michele Cioffi, Patricia Sancho, Marianthi Tatari, Christopher Heeschen, Manuel Hidalgo, Irene Miranda-Lorenzo, J. Kleeff, Elena Garcia, Gonzalo Gómez-López, Susana García-Silva, Yolanda Sanchez-Ripoll
Publikováno v:
Biblos-e Archivo. Repositorio Institucional de la UAM
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This is the peer reviewed version of the following article: Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment. Gut 64.12 (2015): 1921-1935 and which has been published in final f
Autor:
Patricia Sancho, Isabel Fabregat
Publikováno v:
TGF-β in Human Disease ISBN: 9784431544081
Liver fibrosis is the final consequence of many chronic liver injuries that later develop in cirrhosis and hepatocellular carcinoma (HCC), which are leading causes of morbidity and mortality worldwide. The transforming growth factor-beta (TGF-β) rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09cb50e4531bfc76ac25f91cc0906384
https://doi.org/10.1007/978-4-431-54409-8_11
https://doi.org/10.1007/978-4-431-54409-8_11
Autor:
Estanis Navarro, Isabel Fabregat, Laia Caja, Jèssica Mainez, Antonia Vinyals, Esther Bertran, Angels Fabra, Miguel M. Murillo, Patricia Sancho
Publikováno v:
Cellular signalling. 21(11)
Treatment of FaO rat hepatoma cells with TGF-beta selects cells that survive to its apoptotic effect and undergo epithelial-mesenchymal transitions (EMT). We have established a cell line (T beta T-FaO, from TGF-beta-treated FaO) that shows a mesenchy
Autor:
Santos A. Susin, Hélène Merle-Béral, Patricia Sancho, Marlène Bras, Marika Sarfati, Gaël Roué, Josep E. Esquerda, Manuel Rubio, Victor J. Yuste, Clémence Virely, Sylvie Baudet, Laurent Chatre, Sandrine Barbier
Publikováno v:
Repositorio Abierto de la UdL
Universitad de Lleida
Recercat. Dipósit de la Recerca de Catalunya
instname
Universitad de Lleida
Recercat. Dipósit de la Recerca de Catalunya
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Background Programmed cell death has been traditionally related with caspase activation. However, it is now accepted that caspase-independent forms of programmed cell death also regulate cell death. In chronic lymphocytic leukemia, CD47 ligation indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::831d4eee608c4c0d6a47c9f8f2e83fc9
https://hdl.handle.net/10459.1/49258
https://hdl.handle.net/10459.1/49258
Autor:
Patricia Sancho, César Roncero, Laia Caja, Isabel Fabregat, Nelson Fausto, Margarita Fernández, Irene Carmona-Cuenca
Publikováno v:
Journal of hepatology. 49(6)
Background/Aims The transforming growth factor-beta (TGF-β) induces apoptosis in hepatocytes through an oxidative stress process. Here, we have analyzed the role of different NADPH oxidase isoforms in the intracellular signalling induced by TGF-β i
Autor:
Mariano Barbacid, Luis Gandía, Paola Martinelli, Catarina R. Vieira, Patrick C. Hermann, Alexandra Aicher, Ricardo de Pascual, Francesc Madriles, Marta Cañamero, Patricia Sancho, Christopher Heeschen, Francisco X. Real, Carmen Guerra, Bruno Sainz, Patrick Michl, Martin Wagner, Thomas M. Gress
Publikováno v:
Gastroenterology
Background & Aims Although smoking is a leading risk factor for pancreatic ductal adenocarcinoma (PDAC), little is known about the mechanisms by which smoking promotes initiation or progression of PDAC. Methods We studied the effects of nicotine admi
Autor:
M.A. Palacios, Adrian M. Ramos, Carlos Fernández, Elena de Blas, M. M. Gómez, Donna Amrán, Patricio Aller, Diego Esteban, Patricia Sancho
Publikováno v:
E-Prints Complutense. Archivo Institucional de la UCM
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E-Prints Complutense: Archivo Institucional de la UCM
Universidad Complutense de Madrid
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E-Prints Complutense: Archivo Institucional de la UCM
Universidad Complutense de Madrid
It has been reported that inhibition of extracellular signal-regulated protein kinases (ERKs) attenuates the toxicity cisplatin (cis-platinum (II)-diammine dichloride) in some cell types. This response was here investigated using human myeloid leukem
Autor:
Robert Eferl, Patricia Sancho, Wolfgang Mikulits, Eva Crosas-Molist, César Roncero, Isabel Fabregat, Conrado M. Fernández-Rodríguez, Fernando Pinedo, Jèssica Mainez, Heidemarie Huber
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45285 (2012)
PLoS ONE
PLoS ONE; Vol 7
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS ONE
PLoS ONE; Vol 7
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
A role for the NADPH oxidases NOX1 and NOX2 in liver fibrosis has been proposed, but the implication of NOX4 is poorly understood yet. The aim of this work was to study the functional role of NOX4 in different cell populations implicated in liver fib
Publikováno v:
BMC Proceedings
BMC Proceedings, Vol 6, Iss Suppl 3, p P13 (2012)
BMC Proceedings, Vol 6, Iss Suppl 3, p P13 (2012)
Protein malnutrition occurs when there is insufficient protein to meet metabolic demands. Previous works have indicated that cycles of protein fasting/refeeding enhance the incidence of early lesions during chemical carcinogenesis in rat liver. The g