Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Naeun Lee"'
Autor:
Riri Kwon, Bong-Ki Hong, Kang-Gu Lee, Eunbyeol Choi, Laurent Sabbagh, Chul-Soo Cho, Naeun Lee, Wan-Uk Kim
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
Checkpoint blockade immunotherapy (CBT) can induce long-term clinical benefits in patients with advanced cancer; however, response rates to CBT vary by cancer type. Cancers of the skin, lung, and kidney are largely responsive to CBT, while cancers of
Autor:
Kang-Gu Lee, Eunbyeol Choi, Wan-Uk Kim, Laurent Sabbagh, Naeun Lee, Chul-Soo Cho, Riri Kwon, Bong-Ki Hong
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundClinical efficacy of T cell-based cancer immunotherapy is limited by the lack of T cell infiltration in the tumor mass, especially in solid tumors. Our group demonstrated previously that leukocyte-specific protein 1 (LSP1), an intracellular
Publikováno v:
Pediatric Gastroenterology, Hepatology & Nutrition. 24:377
Purpose We investigated the association of effector memory (EM) CD8+ T cell and CD4+ T cell immunity with metabolic syndrome (MS). Methods Surface and intracellular staining of peripheral blood mononuclear cells was performed. Anti-interleukin-7 rece
Publikováno v:
SLE, Sjögren’s and APS – clinical aspects (other than treatment).
Background Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with heterogeneous clinical manifestations and is characterised with autoreactive T cells and autoantibody overproduction by activated B cells. Objectives The aims of this
Publikováno v:
Optometry and Vision Science. 92:500-505
Purpose To compare the clinical effectiveness of three types of images for detecting retinal nerve fiber layer (RNFL) defects. Methods Three image sets of 100 subjects (9 normal control subjects, 16 glaucoma suspects, and 75 glaucoma patients) were p
Autor:
Yong Woo Ji, Naeun Lee, Gong Je Seong, Kyung Rim Sung, Chan Yun Kim, Hye Sun Lee, Samin Hong, Hyoung Won Bae
Publikováno v:
Journal of Glaucoma. 24:328-333
Purpose Normal-tension glaucoma (NTG) is a heterogenous disease, and there is still controversy about subclassifications of this disorder. On the basis of spectral-domain optical coherence tomography (SD-OCT), we subdivided NTG with hierarchical clus
Autor:
Naeun Lee, Min Sun Shin, Ruth R. Montgomery, Albert C. Shaw, Seung-Ah Yoo, Subhasis Mohanty, Insoo Kang, Ki Soo Kang
Publikováno v:
Clinical Immunology. 152:101-110
IL-15 is involved in regulating host defense and inflammation. Monocytes produce the biologically active cell surface IL-15 in response to IFN-γ. Although aging can alter the immune system, little is known about whether and how aging affects IFN-γ-
Publikováno v:
Cytokine. 58:332-335
The IL-7 receptor alpha (IL-7Rα) is the high affinity receptor for IL-7 which is essential for T cell homeostasis. We recently reported an age-associated expansion of human effector memory (EM) CD8 + T cells expressing IL-7Rα low (IL-7Rα low ), wh
Publikováno v:
Cellular Immunology. 275:19-23
The differentiation of T helper (Th) cells is critically dependent on cytokine milieu. The innate immune monocytes produce IL-1β which can affect the development of Th17 and Th1 cells that predominantly produce IL-17 and IFN-γ, respectively. Oligos
Autor:
Naeun Lee, Won Woo Lee, Sang Hyun Kim, Insoo Kang, Jin Soo Lee, Min Sun Shin, Seong Wook Kang, Youna Kang
Publikováno v:
Clinical Immunology. 140:84-91
Th17 cells produce IL-17 that plays an important role in host defense. However, little is known about whether aging affects human Th17 cells. Here we demonstrated that healthy elderly people (age ≥ 65) had a decreased frequency of IL-17-producing c