Zobrazeno 1 - 10
of 60
pro vyhledávání: '"M. Solis"'
Autor:
Guangchun Han, Warapen Treekitkarnmongkol, Ansam Sinjab, Tina Cascone, Jichao Chen, Humam Kadara, Ignacio I. Wistuba, Christopher S. Stevenson, Paul Scheet, Edwin R. Parra, Patrick M. Brennan, Luisa M. Solis, Carmen Behrens, Daniel G. Rosen, Jianjun Zhang, Danielle R. Little, Dapeng Hao, Beatriz Sanchez-Espiridion, Ruiping Wang, Linh M. Tran, Kostyantyn Krysan, Junya Fujimoto, John V. Heymach, Seyed Javad Moghaddam, Kieko Hara, Samer Bazzi, Minghao Dang, Avrum Spira, Kyle Chang, Dzifa Y. Duose, Don L. Gibbons, Boris Sepesi, Steven M. Dubinett, Linghua Wang, Elena Bogatenkova, Edwin J. Ostrin, Maria Gabriela Raso, Lauren Averett Byers, Jiexin Zhang, Hitoshi Dejima, Enyu Dai, Junya Fukuoka
Publikováno v:
Cancer Discov
Little is known of the geospatial architecture of individual cell populations in lung adenocarcinoma (LUAD) evolution. Here, we perform single-cell RNA sequencing of 186,916 cells from five early-stage LUADs and 14 multiregion normal lung tissues of
Autor:
Runzhe Chen, Boris Sepesi, Jie Ye, J. Jack Lee, John V. Heymach, Junya Fujimoto, Baili Zhang, Nicholas McGranahan, Jianhua Zhang, Latasha Little, Junya Fukuoka, Harvey I. Pass, Dzifa Y. Duose, Chi Wan Chow, Hitoshi Dejima, Kazuhiro Tabata, Humam Kadara, Alexandre Reuben, Marcos R. Estecio, Jiexin Zhang, Xin Hu, Ara A. Vaporciyan, Jia Wu, Lisha Ying, Curtis Gumbs, Hoa H.N. Pham, Paul Scheet, Myrna C.B. Godoy, Carmen Behrens, Cara Haymaker, P. Andrew Futreal, Dan Su, Jianjun Zhang, Luisa M. Solis, Shawna M Hubert, Edwin R. Parra, Ignacio I. Wistuba, Mara B. Antonoff
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The mechanism by which anti-cancer immunity shapes early carcinogenesis of lung adenocarcinoma (ADC) is unknown. In this study, we characterize the immune contexture of invasive lung ADC and its precursors by transcriptomic immune profiling, T cell r
Autor:
Lixia Diao, Esra A. Akbay, Linghua Wang, Won-Chul Lee, Kwok-Kin Wong, Don L. Gibbons, Luisa M. Solis Soto, Ruiping Wang, Stephen G. Swisher, Jing Wang, Runzhe Chen, Roohussaba Khairullah, You Hong Fan, Alexandre Reuben, Mingrui Zhu, Jack A. Roth, Boris Sepesi, Irene Guijarro Munoz, John V. Heymach, Carmen Behrens, Jianhua Zhang, Jacqulyne P. Robichaux, Marcelo V. Negrao, Humam Kadara, Edwin R. Parra, Monique B. Nilsson, Lorenzo Federico, Tatiana Karpinets, Ignacio I. Wistuba, Chantale Bernatchez, Jianjun Zhang, Daniel J. McGrail, S. Patel, Xiuning Le, Ara A. Vaporciyan, Yasir Elamin, Cara Haymaker, Jun Li, Lauren Averett Byers
Publikováno v:
Journal of Thoracic Oncology. 16:583-600
Introduction Lung adenocarcinomas harboring EGFR mutations do not respond to immune checkpoint blockade therapy and their EGFR wildtype counterpart. The mechanisms underlying this lack of clinical response have been investigated but remain incomplete
Autor:
Prapti A. Patel, Daniel A. Pollyea, Richard D. Press, Brian J. Druker, Ujwal Shinde, Allison M Bock, Srinivas K. Tantravahi, Tauangtham Anekpuritanang, Nicola Long, Jeffrey W. Tyner, Jonathan C. Savage, Shannon K. McWeeney, Tiffany L. Lee, Uma Borate, Robert H. Collins, Srinidhi Radhakrishnan, Guang Fan, Fei Yang, Michael W. Deininger, Daniel Bottomly, Jose M Solis-Ruiz, Cristina E. Tognon, Anupriya Agarwal, Beth Wilmot, Saikripa Radhakrishnan
Publikováno v:
Blood
Inherited predisposition to myeloid malignancies is more common than previously appreciated. We analyzed the whole-exome sequencing data of paired leukemia and skin biopsy samples from 391 adult patients from the Beat AML 1.0 consortium. Using the 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cfdc8eb202d8d2ea24589f629b1ccc9
https://europepmc.org/articles/PMC9211447/
https://europepmc.org/articles/PMC9211447/
Autor:
Robert Tyler Hillman, Gloria Salvo, Preetha Ramalingam, Lauren Averett Byers, Junya Fujimoto, Robert J. Cardnell, Natacha Phoolcharoen, Luisa M. Solis Soto, Matthew Carroll, Michael Frumovitz
Publikováno v:
Int J Gynecol Cancer
ObjectivesWomen with recurrent high-grade neuroendocrine cervical cancer have few effective treatment options. The aim of this study was to identify potential therapeutic targets for women with this disease.MethodsSpecimens from patients with high-gr
Publikováno v:
Virchows Archiv. 477:437-444
Hodgkin lymphoma is a B cell neoplasm characterized by Hodgkin and Reed-Sternberg (HRS) cells in an inflammatory background. Classic Hodgkin lymphoma (CHL) accounts for approximately 90% of all cases of HL and four types are recognized in the World H
Autor:
Frank Rojas, Marcelo V. Negrao, Timothy P. Heffernan, Alexandre Reuben, Younghee Lee, Humam Kadara, Jianjun Zhang, Cheuk Hong Leung, Annikka Weissferdt, Christopher A. Bristow, Stephen G. Swisher, Lorenzo Federico, Apar Pataer, John V. Heymach, Tina Cascone, Hitoshi Dejima, Ara A. Vaporciyan, Alejandro Francisco-Cruz, Edwin R. Parra, Ignacio I. Wistuba, Boris Sepesi, Luisa M. Solis, Chantale Bernatchez, Stephanie Schmidt, William N. William, Don L. Gibbons, Heather Lin, Jack Lee, Haiping Guo, Monika Pradhan, Cara Haymaker
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundHow neoadjuvant chemo-immunotherapy modulates tumor immune composition and response is not completely understood. We interrogate immunomodulation of neoadjuvant platinum-based chemotherapy (C), nivolumab (N), and N-plus-C (NC) and their con
Autor:
Guillermo Garcia-Manero, Dapeng Hao, Edwin R. Parra, Jairo T. Mathews, Naval Daver, Patrick K. Reville, Padmanee Sharma, Auriole Tamegnon, Latasha Little, Koichi Takahashi, Kunal Rai, Jin Seon Im, Feng Wang, Hussein A. Abbas, Wei Wang, Luisa M. Solis, Maomao Ding, Sreyashi Basu, Michael R. Green, Marina Konopleva, James P. Allison, Katarzyna Tomczak, Zoe Alaniz, Gheath Alatrash, Jing Ning, Wei Lu, Mario L. Marques-Piubelli, Andrew Futreal, Steven M. Kornblau, Hannah C. Beird, Praveen Barrodia, Ruiping Wang, Linghua Wang, Jianhua Zhang
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
In contrast to the curative effect of allogenic stem cell transplantation in acute myeloid leukemia via T cell activity, only modest responses are achieved with checkpoint-blockade therapy, which might be explained by T cell phenotypes and T cell rec
Publikováno v:
European Heart Journal. 41
Background Supraventricular arrhythmias represent a diagnostic challenge. Its prevalence and causes are not well established, given the impossibility to differentiate between all different types of supraventricular tachycardias (SVT). There are sever
Autor:
Carmen Behrens, Ying Wei, Bertha Leticia Rodriguez, Jing Wang, Lixia Diao, Edwin Roger Parra Cuentes, Luisa M. Solis Soto, Gabriela Raso, Harold A. Chapman, Ignacio I. Wistuba, David H. Peng, Don L. Gibbons, Jonathan M. Kurie, Lauren Averett Byers, Mitsuo Yamauchi, Limo Chen
Publikováno v:
Nature communications, vol 11, iss 1
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Tumor extracellular matrix has been associated with drug resistance and immune suppression. Here, proteomic and RNA profiling reveal increased collagen levels in lung tumors resistant to PD-1/PD-L1 blockade. Additionally, elevated collagen correlates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5958730d2b99c365ce6f858f71d80ee1
https://escholarship.org/uc/item/63z8b6t4
https://escholarship.org/uc/item/63z8b6t4