Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Liza Makowski"'
Publikováno v:
Cancer Research. 81:PS17-46
Immunotherapy has revolutionized cancer treatment showing unprecedented long-term antitumor responses. However, most patients do not respond to immunotherapies due at least partly to immune suppression. Immunotherapy non-responders have high levels o
Autor:
Sho Morioka, Liyang Zhao, Yunlu Zhu, Sarah Kucenas, Liza Makowski, Christopher B. Medina, Norbert Leitinger, Suna Onengut-Gumuscu, Jeffrey C. Rathmell, Vlad Serbulea, Kodi S. Ravichandran, Justin S. A. Perry, Michael H. Raymond
Publikováno v:
Nature
Development and routine tissue homeostasis require a high turnover of apoptotic cells. These cells are removed by professional and non-professional phagocytes via efferocytosis1. How a phagocyte maintains its homeostasis while coordinating corpse upt
Autor:
Canan Kuscu, Amandeep Bajwa, Daniel Maluf, Thomas V. Rousselle, Maria Namwanje, James D. Eason, Cem Kuscu, Kailo H. Schlegel, Liza Makowski, Liping Huang, V. Mas
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
Dendritic cells (DCs) are central in regulating immune responses of kidney ischemia-reperfusion injury (IRI), and strategies to alter DC function may provide new therapeutic opportunities. Sphingosine 1-phosphate (S1P) modulates immunity through bind
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The tumor microenvironment (TME) is a complex network of epithelial and stromal cells, wherein stromal components provide support to tumor cells during all stages of tumorigenesis. Among these stromal cell populations are myeloid cells, which are com
Autor:
Bernard E. Weissman, Liza Makowski, Tigist Y. Tamir, Stephanie A. Montgomery, Seth J. Weir, Travis P. Schrank, Tuong T. Nguyen, Scott H. Randell, Travis S. Ptacek, D. Neil Hayes, Jeremy M. Simon, Kathleen M. Mulvaney, Brittany M. Bowman, Michael B. Major, Xiaoxin L Chen, Ryan M. Murphy
Publikováno v:
J Pathol
Activation of the nuclear factor (erythroid-derived 2)-like 2 (NFE2L2 or NRF2) transcription factor is a critical and evolutionarily conserved cellular response to oxidative stress, metabolic stress, and xenobiotic insult. Deficiency of NRF2 results
Autor:
Balachandra K. Gorentla, Patrick L. Leslie, Trent A. Waugh, D. Neil Hayes, Jared Weiss, Albert S. Baldwin, Emily B. Harrison, Subrata K. Ghosh, Alessandro Porrello, Yvonne L. Chao, Michele C. Hayward, Alisa S. Wolberg, Sravya Kattula, Alisha Holtzhausen, Matthew D. Wilkerson, Cecilia Oderup, Chad V. Pecot, Liza Makowski, Virginia Godfrey, Sanggyu Bae, Scott H. Randell, H. Shelton Earp, Salma H. Azam
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
Nature Communications
Nature Communications
Lung cancer is the leading cause of cancer-related deaths worldwide, and lung squamous carcinomas (LUSC) represent about 30% of cases. Molecular aberrations in lung adenocarcinomas have allowed for effective targeted treatments, but corresponding the
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A710-A710
BackgroundImmunotherapies that reinvigorate T cell responses have transformed the treatment of many cancers showing unprecedented durable antitumor responses. However, most patients do not respond to immunotherapy due in part to immunosuppression. Im
Publikováno v:
Comprehensive Physiology
Solid tumor growth and metastasis require the interaction of tumor cells with the surrounding tissue, leading to a view of tumors as tissue-level phenomena rather than exclusively cell-intrinsic anomalies. Due to the ubiquitous nature of adipose tiss
Autor:
Alex J. Freemerman, Ashley M. Fuller, J. Ashley Ezzell, Alyssa J. Cozzo, Joseph A. Galanko, Melissa A. Troester, Liza Makowski, Stephen D. Hursting
Publikováno v:
The FASEB Journal. 32
Autor:
Liza Makowski, Alyssa J. Cozzo, Stephanie A. Montgomery, Yuanyuan Qin, Melissa A. Troester, J. Ashley Ezzell, Sneha Sundaram, Kirk K. McNaughton, Alex J. Freemerman, Ottavia Zattra, Joseph A. Galanko, David B. Darr, Luma Essaid
Publikováno v:
SpringerPlus
Epidemiologic studies have associated obesity with increased risk of the aggressive basal-like breast cancer (BBC) subtype. Hepatocyte growth factor (HGF) signaling through its receptor, cMET, is elevated in obesity and is a pro-tumorigenic pathway s