Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Johan van der Vlag"'
Autor:
Jitske Jansen, Marinka Bakker-van Bebber, Fieke Mooren, Markus A. Loeven, Brigith Willemsen, Jennifer Eymael, Catherine Meyer-Schwesinger, Bart Smeets, Shagun Sharma, Jack F.M. Wetzels, Henry B.P.M. Dijkman, Johan van der Vlag, Laura Miesen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, 10
Scientific Reports
Scientific Reports, 10
Scientific Reports
Anti-Thy1.1 transgenic mice develop glomerular lesions that mimic collapsing focal segmental glomerulosclerosis (FSGS) in humans with collapse of the glomerular tuft and marked hyperplasia of the parietal epithelial cells (PECs). Immunostaining of ph
Publikováno v:
Journal of Controlled Release, 328, pp. 762-775
Journal of Controlled Release, 328, 762-775
Journal of Controlled Release, 328, 762-775
Contains fulltext : 229034.pdf (Publisher’s version ) (Open Access) Chronic and acute kidney disease constitute a worldwide health burden, but are still lacking efficient therapeutics. Current medication such as anti-inflammatory steroids causes sy
Autor:
Rafael Kramann, Eric J. Steenbergen, Dirk J W den Braanker, Naomi Parr, Vedran Drenic, Jack F.M. Wetzels, Bart Smeets, Roy Wetzels, Christoph Kuppe, Tom Nijenhuis, Bartholomeus T. van den Berge, Rutger J. Maas, Katharina C Reimer, Helmer Mudde, James Shiniti Nagai, Nicole C. A. J. van de Kar, Martijn van den Broek, Ivan G. Costa, Fieke Mooren, Gianluca Di Giovanni, Brigith Willemsen, Nicole Endlich, Jitske Jansen, Rebekka K. Schneider, Johan van der Vlag, Michiel F. Schreuder, Quincy Nlandu
Nephrotic syndrome (NS) is characterized by severe proteinuria as a consequence of kidney glomerular injury due to podocyte damage. In vitro models mimicking in vivo podocyte characteristics are a prerequisite to resolve NS pathogenesis. Here, we rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a849cfa988909b8feb5e7920ab399ad
https://doi.org/10.1101/2021.10.27.466054
https://doi.org/10.1101/2021.10.27.466054
Autor:
Richard J.H. Smith, David J. Kavanagh, Fadi Fakhouri, Vivette D. D'Agati, Véronique Frémeaux-Bacchi, Gerald B. Appel, Giuseppe Remuzzi, Carla M. Nester, Santiago Rodríguez de Córdoba, Sanjeev Sethi, Mihály Józsi, Marina Noris, Matthew C. Pickering, Johan van der Vlag, Peter F. Zipfel, Anna M. Blom, H. Terence Cook, John D. Lambris
Publikováno v:
Nature Reviews. Nephrology, 15, 129-143
Nature Reviews. Nephrology, 15, 3, pp. 129-143
Nature Reviews. Nephrology, 15, 3, pp. 129-143
Item does not contain fulltext The C3 glomerulopathies are a group of rare kidney diseases characterized by complement dysregulation occurring in the fluid phase and in the glomerular microenvironment, which results in prominent complement C3 deposit
Publikováno v:
PLoS One, 16, 5
PLoS One, 16
PLoS ONE, Vol 16, Iss 5, p e0251129 (2021)
PLoS ONE
PLoS One, 16
PLoS ONE, Vol 16, Iss 5, p e0251129 (2021)
PLoS ONE
Contains fulltext : 235651.pdf (Publisher’s version ) (Open Access) Shear stress induced by laminar blood flow has a profound effect on the morphology and functional phenotype of macrovascular endothelial cells. The influence of laminar flow on the
Publikováno v:
International Journal of Molecular Sciences, 22, 22
International Journal of Molecular Sciences, Vol 22, Iss 12485, p 12485 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 22
International Journal of Molecular Sciences, 22
International Journal of Molecular Sciences, Vol 22, Iss 12485, p 12485 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 22
International Journal of Molecular Sciences, 22
Increased expression and activity of the Ca2+ channel transient receptor potential channel 6 (TRPC6) is associated with focal segmental glomerulosclerosis, but therapeutic strategies to target TRPC6 are currently lacking. Nitric oxide (NO) is crucial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb421e11e74375baf8a6e85f7321eec
https://repository.ubn.ru.nl/handle/2066/241982
https://repository.ubn.ru.nl/handle/2066/241982
Autor:
Fadel Muhammad Garishah, Nils Rother, Silvita Fitri Riswari, Bachti Alisjahbana, Gijs J. Overheul, Ronald P. van Rij, André van der Ven, Johan van der Vlag, Quirijn de Mast
Publikováno v:
Frontiers in Immunology, 12
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Neutrophil extracellular traps (NETs) are increasingly recognized to play a role in the pathogenesis of viral infections, including dengue. NETs can be formed NADPH oxidase (NOX)-dependently or NOX-independently. NOX-independent NETs can be induced b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea99df09f8a6f9157b620a0fdf451dd1
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/234201
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/234201
Autor:
Marloes Sol, Jacob van den Born, Johan van der Vlag, Marius C. van den Heuvel, Guido Krenning, Jan-Luuk Hillebrands, Jan A. A. M. Kamps
Publikováno v:
Frontiers in Pharmacology, 11
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 11 (2020)
Contains fulltext : 229604.pdf (Publisher’s version ) (Open Access) Glomerular endothelial cell (GEnC) dysfunction is important in the pathogenesis of glomerular sclerotic diseases, including Focal Segmental Glomerulosclerosis (FSGS) and overt diab
Autor:
Johan van der Vlag, Baranca Buijsers
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030345204
The primary filtration of blood occurs in the glomerulus in the kidney. Destruction of any of the layers of the glomerular filtration barrier might result in proteinuric disease. The glomerular endothelial cells and especially its covering layer, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e40592ec8482c09323c034ee42c7f23
https://doi.org/10.1007/978-3-030-34521-1_26
https://doi.org/10.1007/978-3-030-34521-1_26
Autor:
Jack F.M. Wetzels, Fieke Mooren, Johan van der Vlag, Jennifer Eymael, Jitske Jansen, Bart Smeets, Laura Miesen
Publikováno v:
Journal of Visualized Experiments, 162
Contains fulltext : 225122.pdf (Publisher’s version ) (Closed access) Parietal epithelial cell (PEC) activation is one of the key factors involved in the development and progression of glomerulosclerosis. Inhibition of pathways involved in parietal