Zobrazeno 1 - 10
of 69
pro vyhledávání: '"J Aitken"'
Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes
Autor:
Clare Megson, Anna E. Long, Isabel V. Wilson, F. Susan Wong, Rachel J Aitken, Stephanie J. Hanna, Kathleen M Gillespie, Joanne Boldison
Publikováno v:
Diabetologia
Boldison, J, Long, A E, Aitken, R J, Wilson, I V, Hanna, S, Wong, F S & Gillespie, K M 2022, ' Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes ', Diabetologia, vol. 65, no. 2, pp. 343-355 . https://doi.org/10.1007/s00125-021-05595-0
Boldison, J, Long, A E, Aitken, R J, Wilson, I V, Hanna, S, Wong, F S & Gillespie, K M 2022, ' Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes ', Diabetologia, vol. 65, no. 2, pp. 343-355 . https://doi.org/10.1007/s00125-021-05595-0
Aims/hypothesis Slow progressors to type 1 diabetes are individuals positive for multiple pancreatic islet autoantibodies who have remained diabetes-free for at least 10 years; regulation of the autoimmune response is understudied in this group. Here
Autor:
Stephanie J. Hanna, Claire Megson, Kathleen M Gillespie, Isabel V. Wilson, Anna E. Long, F. Susan Wong, Joanne Boldison, Rachel J Aitken
ObjectiveTo profile CD4+ regulatory T cells (Tregs) in a well-characterised cohort of slow progressors to type 1 diabetes, individuals positive for multiple islet autoantibodies who remain diabetes-free for at least 10 years.Research Design and Metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2899780e02b66f97150344332cddb3e
https://doi.org/10.1101/2021.01.13.21249751
https://doi.org/10.1101/2021.01.13.21249751
Publikováno v:
Annals of Oncology. 21:1254-1261
Background Assessment of receptors [estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2)] is routinely carried out on primary tumour in order to select appropriate adjuvant therapy; the same analysis
Autor:
Uta Frith, Kenneth J. Aitken
Publikováno v:
Developmental Medicine & Child Neurology. 33:930-934
Autor:
Brendan E.L. Adams, Damian E. Myers, Mark A. Kirkland, Geoffrey C. Nicholson, C. J. Aitken, Carolina M. Lopez, Jason M. Hodge, Caryll M Waugh
Publikováno v:
Journal of Bone and Mineral Research. 19:190-199
Human osteoclasts can be efficiently generated in vitro from cord blood mononuclear cells and derived CFU-GM colonies. However, CFU-M colonies are poorly osteoclastogenic. Short-term (2–48 h) treatment with GM-CSF stimulates osteoclast formation by
Publikováno v:
Physical & Occupational Therapy In Geriatrics. 21:67-78
Cerebrovascular accidents (CVA) are the leading cause of long-term disability. About 600,000 Americans will have a stroke this year (American Heart Association, 2002). It is estimated that between 29% and 75% of those who suffer from strokes will be
Autor:
Damian E. Myers, Geoffrey C. Nicholson, Jason M. Hodge, Nigel Alexander Morrison, Tanya Vaughan, C. J. Aitken
Publikováno v:
Journal of Bone and Mineral Research. 18:S175-S285
Using gene array analysis, we found that thioredoxin (TRX) binding protein-2 (TBP-2) was down-regulated during osteoclast (OC) differentiation. TBP-2 is a negative regulator of TRX, a small protein with a redox-active dithiol active site. TRX enhance
Autor:
K K Singh, R J Aitken
Publikováno v:
British Journal of Surgery. 86:1332-1336
Background The surgeon is an important variable that influences outcome following colorectal cancer surgery. Operative training of suitable quality and quantity is essential if intersurgeon variation is to be reduced. The aim of this study was to exa
Publikováno v:
International Journal of Plant Sciences. 156:404-416
The reproductive cycle of Kauri (Agathis australis) lasts about 18 mo in New Zealand. Pollination occurs in October and seeds are mature in March. Prefertilization stages were described in a previous study. In October, about 1 yr after pollination, m
Autor:
Colwyn Trevarthen, Kenneth J. Aitken
Publikováno v:
Development and Psychopathology. 6:597-633
Disorders of emotion, communication, and learning in early childhood are considered in light of evidence on human brain growth from embryo stages. We cite microbehavioral evidence indicating that infants are born able to express the internal activity