Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Iqbal S"'
Publikováno v:
Trends in Biotechnology. 39:298-310
Intracellular delivery of therapeutic antibodies is highly desirable but remains a challenge for biomedical research and the pharmaceutical industry. Approximately two-thirds of disease-associated targets are found inside the cell. Difficulty blockin
Publikováno v:
Trends in Pharmacological Sciences. 42:45-59
Conventional αβ CAR-T cell-based approaches have revolutionized the field of cancer immunotherapy, but hurdles remain, especially for solid tumors. Novel strategies in conjunction with alternative cell types are therefore required for effective CAR
Autor:
Louise Brown, Richard Hindley, Derek J. Rosario, Maneesh Ghei, Shonit Punwani, Elena Frangou, Solon Karapanagiotis, Hashim U. Ahmed, Iqbal S. Shergill, Mathias Winkler, Lina M. Carmona Echeverria, Alex Kirkham, Alastair Henderson, Tim Dudderidge, Simon Bott, Francesco Giganti, Vasilis Stavrinides, Tom Syer, Richard Kaplan, Mark Emberton, Chris Parker, Dean C. Barratt, Raj Persad, Joseph M. Norris, Hayley C. Whitaker, Ahmed El-Shater Bosaily, Robert Oldroyd, Nicholas Burns-Cox, Alex Freeman, Yipeng Hu
Publikováno v:
European Urology
Background False positive multiparametric magnetic resonance imaging (mpMRI) phenotypes prompt unnecessary biopsies. The Prostate MRI Imaging Study (PROMIS) provides a unique opportunity to explore such phenotypes in biopsy-naïve men with raised pro
Autor:
Iqbal S. Shergill, Mohamed Yehia, Sanjay K. Agarwal, Christian Seipp, Basharat Jameel, Stephen Hughes, Abigail Duckett
Publikováno v:
Journal of Advances in Medicine and Medical Research. :63-70
Introduction: With the recent introduction of Multiparametric MRI (MP-MRI) for suspected prostate cancer, we investigated the clinic-pathological outcome of men who were suspected to have prostate cancer but in whom initial MP-MRI was negative (Liker
Autor:
Elena Frangou, Jeevan Kumaradevan, Sanjay K. Agarwal, J Smart, Janice Ash-Miles, Hywel Evans, Charles Jameson, Alex Freeman, Nick Burns-Cox, Paul Burn, Richard Hindley, Andrew Thrower, Louise Brown, Raj Prasad, Alastair Henderson, Alexander Kirkham, Tim Dudderidge, Mark Emberton, Victoria Stewart, Simon Bott, Maneesh Ghei, Hashim U. Ahmed, Derek J. Rosario, Ferekh Salim, Iqbal S. Shergill, Ken Tung, Richard Kaplan, Tara Barwick, Shonit Punwani, Sukanya Ghosh, Delia Peppercorn, Mathias Winkler, Ahmed El-Shater Bosaily
Publikováno v:
European Urology. 78:503-511
Background Multiparametric magnetic resonance imaging (MP-MRI) is established in the diagnosis of prostate cancer, but the need for enhanced sequences has recently been questioned. Objective To assess whether dynamic contrast-enhanced imaging (DCE) i
Autor:
Sacha Moore, Gidon Ellis, Asad Saleemi, Stephen Hughes, Farooq Khan, Christopher Bell, Iqbal S. Shergill, Amarit Gill, Obinna Obi-Njoku
Publikováno v:
BMC Urology, Vol 19, Iss 1, Pp 1-7 (2019)
BMC Urology
BMC Urology
Background We investigated the surgical feasibility, safety and effectiveness of 50 W (low power) Holmium Laser enucleation of the prostate (HoLEP) in patients who have undergone previous template biopsy of the prostate (TPB). Methods Data encompassi
Autor:
Christopter Cook, Neil Ruparelia, Sayan Sen, Henry Seligman, Christopher Rajkumar, Nearchos Hadjiloizou, Ben Ariff, Iqbal S. Malik, Richard J. Jabbour, Ghada W. Mikhail
Publikováno v:
Cardiovascular Revascularization Medicine. 21:33-35
Autor:
Judith E. Allen, David E. Newby, Adriano G. Rossi, Adrian Thomson, Iqbal S Toor, Dominik Rückerl, Iris Mair, Gillian A. Gray
Publikováno v:
Toor, I S, Rückerl, D, Mair, I, Thomson, A, Rossi, A G, Newby, D E, Allen, J E & Gray, G A 2019, ' Enhanced monocyte recruitment and delayed alternative macrophage polarisation accompanies impaired repair following myocardial infarction in C57BL/6 compared to BALB/c mice ', Clinical and experimental immunology . https://doi.org/10.1111/cei.13330, https://doi.org/10.1111/cei.13330
Clinical and Experimental Immunology
Toor, I S, Rückerl, D, Mair, I, Thomson, A, Rossi, A G, Newby, D E, Allen, J E & Gray, G A 2019, ' Enhanced monocyte recruitment and delayed alternative macrophage polarization accompanies impaired repair following myocardial infarction in C57BL/6 compared to BALB/c mice ', Clinical & Experimental Immunology . https://doi.org/10.1111/cei.13330
Clinical and Experimental Immunology
Toor, I S, Rückerl, D, Mair, I, Thomson, A, Rossi, A G, Newby, D E, Allen, J E & Gray, G A 2019, ' Enhanced monocyte recruitment and delayed alternative macrophage polarization accompanies impaired repair following myocardial infarction in C57BL/6 compared to BALB/c mice ', Clinical & Experimental Immunology . https://doi.org/10.1111/cei.13330
Summary Activation of the innate immune response following myocardial infarction (MI) is essential for infarct repair. Preclinical models of MI commonly use C57BL/6 mice, which have a type 1-dominant immune response, whereas other mouse strains such
Autor:
Vincent Khoo, Stuart McCracken, John J. McGrath, Hashim U. Ahmed, Derek J. de Solla Price, Bijan Khoubehi, Nicola Anyamene, O. Naismith, Cathryn Brock, Emily Day, Martin Evans, Azman Ibrahim, Giles Hellawell, Kamalram Thippu Jayaprakash, John Staffurth, Catherine Heath, R. Pearson, Stephen Mangar, Martin J. Connor, Johanna Sukumar, Denise Sheehan, Naveed Sarwar, Dolan Basak, Manal Kumar, Alison Falconer, Bhavan Prasad Rai, Shiva Gayadeen, Michael Gonzalez, Natalia Klimowska-Nassar, Mathias Winkler, Tim Dudderidge, Iqbal S. Shergill, Francesca Fiorentino, Taimur T. Shah, Gail Horan, Katarzyna Smigielska
Publikováno v:
BMJ Open
BMJ Open, Vol 11, Iss 2 (2021)
BMJ Open, Vol 11, Iss 2 (2021)
IntroductionSurvival in men diagnosed with de novo synchronous metastatic prostate cancer has increased following the use of upfront systemic treatment, using chemotherapy and other novel androgen receptor targeted agents, in addition to standard and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd6f4b4da88ad47cb06c223e2da89ca
Autor:
Alyson Jayne Moyes, Nana Yaa Frempomaa Snyper, Stephen Hughes, Peter Ella-tongwiis, Iqbal S. Shergill, Rebecca May Lamb
Publikováno v:
European Journal of Medical Research
European Journal of Medical Research, Vol 25, Iss 1, Pp 1-10 (2020)
European Journal of Medical Research, Vol 25, Iss 1, Pp 1-10 (2020)
Background The number of patients undergoing flexible ureterenoscopy (FURS) for the treatment of kidney stones (renal calculi) is increasing annually, and as such the development of post-operative complications, such as acute kidney injury (AKI), hae