Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Haydn T. Kissick"'
Autor:
Maria Cardenas, Mihir R. Patel, John Sidney, Alessandro Sette, Dong M. Shin, Mary Carrington, Tahseen H. Nasti, Haydn T. Kissick, Rafi Ahmed, Xu Wang, Zhuo Georgia Chen, Nataliya Prokhnevska, Andreas Wieland, Rebecca C. Obeng, Christopher C. Griffith, Se Jin Im, Nabil F. Saba, Christiane S Eberhardt
Publikováno v:
Nature
T cells are important in tumour immunity but a better understanding is needed of the differentiation of antigen-specific T cells in human cancer1,2. Here we studied CD8 T cells in patients with human papillomavirus (HPV)-positive head and neck cancer
Autor:
Xu Wang, Haydn T. Kissick, Andreas Wieland, Nabil F. Saba, Mihir R. Patel, William H. Hudson, Rafi Ahmed, Christiane S Eberhardt, Zhuo Georgia Chen, Maria Cardenas, Christopher C. Griffith, Rebecca C. Obeng
Publikováno v:
Nature. 597:274-278
Tumours often contain B cells and plasma cells but the antigen specificity of these intratumoral B cells is not well understood1-8. Here we show that human papillomavirus (HPV)-specific B cell responses are detectable in samples from patients with HP
Autor:
Pragati Sharma, Mohit Singla, Kamalvishnu P. Gottimukkala, Rakesh Lodha, Pushpendra Singh, Sivaram Gunisetty, Sanjeev Kumar, Priya Bhatnagar, Anmol Chandele, Guruprasad R. Medigeshi, Harekrushna Panda, Kaja Murali-Krishna, Yadya M Chawla, Kaustuv Nayak, Charu Aggarwal, Rafi Ahmed, Carl W. Davis, Sushil K. Kabra, Keshav Saini, Elluri Seetharami Reddy, Haydn T. Kissick, Deepti Maheshwari
Publikováno v:
J Virol
Previous studies have shown that plasmablasts expand massively in dengue patients as compared to many other situations such as influenza infection or vaccination. However, a detailed understanding of the phenotypes and transcriptional features of the
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundCD4 T cells can differentiate into multiple effector subsets that can mediate variable functions. In this work we aim to understand how CD4 T cells differentiate in response to tumor antigens and their respective function in the anti-tumor
Autor:
Haydn T. Kissick, Maria Cardenas, Jennifer W Carlisle, Adeboye O. Osunkoya, Caroline S. Jansen, Viraj A. Master, Patrick Mullane, Mehmet Asim Bilen, Rachel Greenwald, Ewelina Sobierajska, Nataliya Prokhnevska
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundTumor infiltrating T-cells have a prognostic benefit in many tumor types,1–8 and we recently sought to determine whether the level of T-cell infiltration into renal tumors predicts clinical outcomes. In our recent publication,9 we showed
Autor:
Weiwen Zhang, Anna B. Morris, Erica V. Peek, Geeta Karadkhele, Jennifer M. Robertson, Haydn T. Kissick, Christian P. Larsen
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Cytomegalovirus (CMV) is one of the most commonly recognized opportunistic pathogens and remains the most influential known parameter in shaping an individual’s immune system. As such, T cells induced by CMV infection could have a long-term impact
Autor:
Sabina Signoretti, Steven P. Balk, Carla Calagua, Adam G. Sowalsky, Ross Lake, Haydn T. Kissick, David B. Sykes, Olga Voznesensky, Huihui Ye, Scott Wilkinson, Caroline S. Jansen, Taghreed Hirz, David J. Einstein, Anson T. Ku, Miriam Ficial, Philip J. Saylor, Luke del Balzo
PurposeA subset of primary prostate cancer (PCa) expresses programmed death-ligand 1 (PD-L1), but whether they have unique tumor immune microenvironment (TIME) or genomic features is unclear.Experimental DesignWe selected PD-L1-positive high-grade an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c0b91971cc94704a96381a9b6c6a0c4
https://doi.org/10.1101/2021.01.27.21250464
https://doi.org/10.1101/2021.01.27.21250464
Autor:
Caroline S. Jansen, Miriam Ficial, Ross Lake, Scott Wilkinson, Olga Voznesensky, Luke del Balzo, Adam G. Sowalsky, Philip J. Saylor, Steven P. Balk, Carla Calagua, David J. Einstein, Taghreed Hirz, David B. Sykes, Huihui Ye, Haydn T. Kissick, Anson T. Ku, Sabina Signoretti
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 27(17)
Purpose: A subset of primary prostate cancer expresses programmed death-ligand 1 (PD-L1), but whether they have a unique tumor immune microenvironment or genomic features is unclear. Experimental Design: We selected PD-L1–positive high-grade and/or
Autor:
Susan N. Thomas, David M. Francis, Margaret P. Manspeaker, Meghan J. O'Melia, Haydn T. Kissick, Nathan A. Rohner
Publikováno v:
Science Advances. 6
Revealing the mechanisms that underlie the expansion of antitumor CD8+ T cells that are associated with improved clinical outcomes is critical to improving immunotherapeutic management of melanoma. How the lymphatic system, which orchestrates the com
Autor:
Meghan J. O'Melia, Edmund K. Waller, Brian Pollack, Alex Schudel, David M. Francis, Margaret P. Manspeaker, Haydn T. Kissick, Susan N. Thomas, Lauren F. Sestito
Publikováno v:
Science translational medicine
Systemic administration of immune checkpoint blockade (ICB) monoclonal antibodies (mAbs) can unleash antitumor functions of T cells but is associated with variable response rates and off-target toxicities. We hypothesized that antitumor efficacy of I