Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Hans M.G. Princen"'
Autor:
Tsai-Sang Dederichs, Peter Kohl, Katja Krebs, Clinton S. Robbins, Dennis Wolf, Bianca Dufner, Jiadai Zou, E.J. Pieterman, Timo Heidt, Christopher Starz, Rafael Kaeser, Natalie Hoppe, Peter Stachon, Tobias Boettler, Carmen Härdtner, Benoît Ho-Tin-Noé, Hans M.G. Princen, Florian Willecke, Andreas Zirlik, Diana Sharipova, Carolin A. Ehlert, Filip K. Swirski, Constantin von zur Mühlen, Alina Jander, Ingo Hilgendorf, Christoph Bode, Josef Madl, Simon Rauterberg, Jan Kornemann
Publikováno v:
Basic Research in Cardiology
Statins induce plaque regression characterized by reduced macrophage content in humans, but the underlying mechanisms remain speculative. Studying the translational APOE*3-Leiden.CETP mouse model with a humanized lipoprotein metabolism, we find that
Autor:
Brygida Marczyk, Stefan Chlopicki, Agnieszka Jasztal, Anna Bar, Hans M.G. Princen, Anna Kurpińska, Karolina Matyjaszczyk-Gwarda, Elsbet J. Pieterman, Agnieszka Kaczor, Joanna Suraj-Prazmowska, Bartosz Proniewski, Maria Walczak, Zuzanna Majka, Edyta Kuś, Krzysztof Czamara, Anna Kieronska-Rudek
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Long‐term feeding with a high‐fat diet (HFD) induces endothelial dysfunction in mice, but early HFD‐induced effects on endothelium have not been well characterized. Methods and Results Using an magnetic resonance imaging‐based meth
Autor:
Bianca Dufner, Dennis Wolf, Ingo Hilgendorf, Jan Kornemann, Natalie Hoppe, Peter Stachon, Andreas Zirlik, Hans M.G. Princen, C. Haerdtner, C. Bode, Katja Krebs
Publikováno v:
European Heart Journal. 40
Background Guidelines recommend cholesterol lowering for primary and secondary prevention of cardiovascular disease. While lipid lowering has been reported to induce plaque regression, the underlying mechanisms have remained speculative. Purpose We h
Autor:
Elsbet J. Pieterman, Marianne G. Pouwer, Lori L. Jennings, Alain J. van Gool, Jan H.N. Lindeman, Maarten D. Sollewijn Gelpke, Danielle van Keulen, Hans M.G. Princen, Vilmundur Gudnason, Valur Emilsson, Gerard Pasterkamp, Kim Holmstrøm, Ljubica Perisic Matic, Boye Schnack Nielsen, Dennie Tempel, Ulf Hedin
Publikováno v:
PLoS ONE, 14(8). Public Library of Science
Plos One, 8, 14, e0221477
PLoS ONE
PLoS ONE, 14(8). PUBLIC LIBRARY SCIENCE
PLoS ONE, Vol 14, Iss 8, p e0221477 (2019)
Plos One, 8, 14, e0221477
PLoS ONE
PLoS ONE, 14(8). PUBLIC LIBRARY SCIENCE
PLoS ONE, Vol 14, Iss 8, p e0221477 (2019)
ObjectivePrevious studies indicate a role for Oncostatin M (OSM) in atherosclerosis and other chronic inflammatory diseases for which inhibitory antibodies are in development. However, to date no intervention studies with OSM have been performed, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9390ed769904473deef47d2afd5dee3
https://dspace.library.uu.nl/handle/1874/390802
https://dspace.library.uu.nl/handle/1874/390802
Autor:
Elsbet H. Pieterman, Hans M.G. Princen, Andrea D. van Dam, Patrick C.N. Rensen, Jimmy F.P. Berbée, Eveline Gart, Yanan Wang, Isabel M. Mol, Albert K. Groen, Henk G. Klop, Geerte Hoeke, Susan M. van den Berg, Mariëtte R. Boon
Publikováno v:
Atherosclerosis, 267, 116-126. Elsevier Ireland Ltd
Atherosclerosis, 267, 116-126
ATHEROSCLEROSIS, 267, 116-126. ELSEVIER IRELAND LTD
Atherosclerosis, 267, 116-126
ATHEROSCLEROSIS, 267, 116-126. ELSEVIER IRELAND LTD
Background and aims: Activation of brown adipose tissue (BAT) reduces both hyperlipidemia and atherosclerosis by increasing the uptake of triglyceride-derived fatty acids by BAT, accompanied by formation and clearance of lipoprotein remnants. We test
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e4e09c990fbeeb1e6bf67c481d4b50d
http://resolver.tudelft.nl/uuid:90ba63af-b55b-4f42-9ad0-1665c007760e
http://resolver.tudelft.nl/uuid:90ba63af-b55b-4f42-9ad0-1665c007760e
Publikováno v:
European Journal of Clinical Nutrition. 54:757-763
Firstly, to study the effect of tea and tea polyphenols on cardiovascular risk indicators of the inflammatory system (IL6, IL1beta and TNF-alpha, CRP), and on haemostasis and endothelial proteins with an acute phase behaviour (fibrinogen, vWF, PAI-1,
Autor:
Gene Liau, Hans M.G. Princen, José W.A. van der Hoorn, Anita M. van den Hoek, J. Wouter Jukema, Louis M. Havekes, Susan Kühnast
Publikováno v:
Journal of Hypertension, 1, 30, 107-116
Journal of Hypertension, 30(1), 107-116
Journal of Hypertension, 30(1), 107-16
Journal of Hypertension, 30(1), 107-116
Journal of Hypertension, 30(1), 107-16
Objective: Aliskiren is the first commercially available, orally active, direct renin inhibitor approved to treat hypertension. The renin-angiotensin system has been shown to be a significant contributor to the development of hypercholesterolemia-ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcbe2be8b56e63327af1e3e80f95671b
https://hdl.handle.net/1887/111167
https://hdl.handle.net/1887/111167
Autor:
A.F.M. Kardinaal, Wendy M R van Herpen-Broekmans, Henk F J Hendriks, Cornelis Kluft, Ineke A. A. Klöpping-Ketelaars, Michiel L. Bots, Geert van Poppel, Hans M.G. Princen, Lilian B M Tijburg
Publikováno v:
European Journal of Epidemiology, 10, 19, 915-921
Background: Endothelial cell dysfunction may be related to an increase in cellular oxidative stress. Carotenoids and vitamins could have an antioxidant-mediated tempering influence on endothelial function and inflammation, thereby reducing the risk o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8071eb555ce4f5c4d2449586fc5d36e7
http://resolver.tudelft.nl/uuid:2c461140-d17d-431d-95ed-7b223beb43c0
http://resolver.tudelft.nl/uuid:2c461140-d17d-431d-95ed-7b223beb43c0
Autor:
Hans M.G. Princen, Martine Deckers, Victor W.M. van Hinsbergh, Paul H.A. Quax, M.R. de Vries, J.H.P. Lardenoye, D. J. M. Delsing, J.H. van Bockel, Louis M. Havekes
Publikováno v:
Lardenoye, J H, Delsing, D J, de Vries, M R, Deckers, M M, Princen, H M G, Havekes, L M, van Hinsbergh, V W M, van Bockel, J H & Quax, P H A 2000, ' Accelerated atherosclerosis by placement of a perivascular cuff and a cholesterol-rich diet in ApoE*3 Leiden transgenic mice. ', Circulation Research, vol. 87, no. 3, pp. 248-53 . https://doi.org/10.1161/01.res.87.3.248
Scopus-Elsevier
Circulation Research, 87(3), 248-53. Lippincott Williams and Wilkins
Europe PubMed Central
Circulation Research, 3, 87, 248-253
Scopus-Elsevier
Circulation Research, 87(3), 248-53. Lippincott Williams and Wilkins
Europe PubMed Central
Circulation Research, 3, 87, 248-253
Intimal hyperplasia after vascular injury is usually studied in animal models with healthy, normocholesterolemic animals. Here, we assess the effect of diet-induced hypercholesterolemia on the induction of intimal hyperplasia in ApoE*,3Leiden mice. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec54103c9837def3a078ae258643897
https://research.vumc.nl/en/publications/02e4d575-4ef2-42c0-81ec-5b6a9c0fa9c4
https://research.vumc.nl/en/publications/02e4d575-4ef2-42c0-81ec-5b6a9c0fa9c4
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology, 11, 17, 3064-3070
Scopus-Elsevier
Scopus-Elsevier
Abstract Consumption of boiled coffee raises serum cholesterol levels in humans. The diterpenes cafestol and kahweol in boiled coffee have been found to be responsible for the increase. To investigate the biochemical background of this effect, we stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c34aeb42b6bffb7c92e3f90eb2222e6
http://resolver.tudelft.nl/uuid:b02f5804-4379-4221-a42d-81fe11dd37f2
http://resolver.tudelft.nl/uuid:b02f5804-4379-4221-a42d-81fe11dd37f2