Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Denise D. Belsham"'
Publikováno v:
Masterclass in Neuroendocrinology ISBN: 9783030623821
Obesity and its comorbidities are increasing at an alarming rate worldwide. A key mechanism in the development of this disease involves dysregulation of the hypothalamus, which is a key region of the brain responsible for maintaining energy balance.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7aee2386662473a15e9ad0112196477b
https://doi.org/10.1007/978-3-030-62383-8_7
https://doi.org/10.1007/978-3-030-62383-8_7
Autor:
Denise D. Belsham, Prasad S. Dalvi
Publikováno v:
Bio Protoc
Immunofluorescence is a reliable method for identifying specific proteins in neuronal and glial cell populations of the hypothalamus. Several immunofluorescence protocols are available to detect protein markers and neuropeptides in the hypothalamus;
The hypothalamus is a vital and an integral part of the central nervous system as it regulates a wide range of physiological and psychological processes, including energy homeostasis, reproduction, circadian rhythms, as well as emotional and behavior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c31d1d72adbf2b81797a7f2e0764ac78
https://doi.org/10.1016/b978-0-12-819801-8.00002-8
https://doi.org/10.1016/b978-0-12-819801-8.00002-8
Publikováno v:
Molecular and Cellular Endocrinology. 438:18-26
Diet-induced obesity can lead to detrimental chronic disorders. The severity of this global epidemic has encouraged ongoing research to characterize the mechanisms underlying obesity and its comorbidities. Recent evidence suggests that saturated fatt
Autor:
Rafael Pineda, Alfonso Paredes, E. Torres, Francisco Ruiz-Pino, María Jesús Vázquez, Miguel López, Juan M. Castellano, Manuel Tena-Sempere, Daniela Fernandois, María S. Avendaño, Núria Casals, Elvira Rodríguez-Vázquez, Inmaculada Velasco, Denise D. Belsham, Matias Rubio, Francisco Gaytan, Carlos Dieguez, Violeta Heras, Juan Carlos Roa, Leonor Pinilla
Publikováno v:
Cell Metab
Childhood obesity, especially in girls, is frequently bound to earlier puberty, which is linked to higher disease burden later in life. The mechanisms underlying this association remain elusive. Here we show that brain ceramides participate in the co
Publikováno v:
Neuroendocrinology. 107(4)
Background and Objectives: Elevated levels of saturated fatty acids (SFA) induce a state of neuroinflammation in the hypothalamus. It has been suggested that microglia sense palmitate, a prevalent circulating SFA, and act as mediators of this inflamm
Autor:
Denise D. Belsham, Neruja Loganathan
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 311(2)
The hypothalamus is responsible for the control of many of our physiological responses, including energy homeostasis. Of interest, there are a number of instances of sexual dimorphism documented with regard to metabolic processes. This review will di
Autor:
Tiffany Ng, John D. Watson, Dhan Chand, Paul C. Boutros, Arij Al Chawaf, David A. Lovejoy, Lifang Song, Denise D. Belsham
Publikováno v:
Regulatory Peptides. 174:79-89
The teneurins are a family of four large transmembrane proteins that are highly expressed in the central nervous system (CNS) where they have been implicated in development and CNS function. At the tip of the carboxyl terminus of each teneurin lies a
Autor:
Sandeep S. Dhillon, Denise D. Belsham
Publikováno v:
International Journal of Obesity. 35:198-207
Estrogen (E(2)) has an inhibitory effect on food intake by acting centrally in the hypothalamus, although it is not clear which hypothalamic neurons are involved in this process. Earlier studies from our lab and others have implicated neuropeptide Y
Publikováno v:
The Analyst. 135:289-295
Isolation of neurons from animal tissue is an important aspect of understanding basic biochemical processes such as the action of hormones and neurotransmitters. In the present work, the focus is on an effort to evaluate the utility of acoustic wave