Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Charles R. Mackay"'
Autor:
Juliana Echevarria-Lima, Leandro Araujo Lobo, Charles R. Mackay, Dario S. Zamboni, Robson Coutinho-Silva, Ana Carolina Oliveira, Julio Scharfstein, Regina Maria Cavalcanti Pilotto Domingues, Aline Cristina Abreu Moreira-Souza, Eliana Mariño, Erivan Schnaider Ramos-Junior, Maria Bellio, Eliane de Oliveira Ferreira, Juliana P Castelpoggi, Bruno Jennings-Almeida
Publikováno v:
The Journal of Immunology. 206:2441-2452
Intestinal barrier is essential for dietary products and microbiota compartmentalization and therefore gut homeostasis. When this barrier is broken, cecal content overflows into the peritoneal cavity, leading to local and systemic robust inflammatory
The skin environment controls local dendritic cell differentiation and function through innate IL-13
Autor:
Kerry L Hilligan, Luis Munoz-Erazo, Lisa M Connor, Sally Chappell, Alan Sher, Franca Ronchese, Charles R. Mackay, Olivier Lamiable, Graham Le Gros, Jianping Yang, Dragana Jankovic, Kirsty A. Wakelin, Matthew R. Hepworth, David Eccles, Greta R Webb, Frank Brombacher, Evelyn J Hyde, Jodie Chandler, Samuel I Old, Roxane Tussiwand, Rita G. Domingues, Johannes U Mayer, Shiau-Choot Tang
The signals driving the adaptation of type-2 dendritic cells (DC2s) to diverse peripheral environments are not well understood. We show that the development of CD11blow migratory DC2s, a DC2 population unique to the dermis, requires STAT6- and KLF4-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a3c3ad77cbcaf7b0a32bb495053eddc
https://doi.org/10.1101/2021.01.05.425466
https://doi.org/10.1101/2021.01.05.425466
Autor:
Charles R. Mackay, Véronique J. Moulin, Mark Slevin, Lucas Felipe Fernandes Bittencourt, Pollyana Ribeiro Castro, Lucíola S. Barcelos, SP Silvia Passos Andrade Andrade, Sébastien Larochelle
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 320(3)
Butyrate is a short-chain fatty acid (SCFA) derived from microbiota and is involved in a range of cell processes in a concentration-dependent manner. Low concentrations of sodium butyrate (NaBu) were shown to be proangiogenic. However, the mechanisms
Autor:
Charles R. Mackay, David M. Tarlinton, Inge Baas, Dana Piovesan, Andrea Di Pietro, Yunshun Chen, Kristy O'Donnell, Jessica C Tempany, Victor Peperzak, Gordon K. Smyth, Kim L. Good-Jacobson, Gabrielle T. Belz, Callisthenis Yiannis, Joanna R Groom
Publikováno v:
Cell Reports, Vol 19, Iss 3, Pp 461-470 (2017)
Summary: Humoral immune responses are tailored to the invading pathogen through regulation of key transcription factors and their networks. This is critical to establishing effective antibody-mediated responses, yet it is unknown how B cells integrat
Autor:
Steven Joung, Michael J. Peek, Ron Benzie, Charles R. Mackay, Kahlia Wong, David P. Eviston, Martin O'Hely, Eliana Mariño, Mingjing Hu, Yu Anne Yap, James L. Richards, David Wilson, Ann Louise Ponsonby, Ralph Nanan, Peter Hsu, Ann Quinton, Ann P. Chidgey, Peter Vuillermin, Mimi L.K. Tang, Jane E. Dahlstrom, Brigitte Santner-Nanan, Norelle L. Daly, Laurence Macia, Fiona Collier
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications
Maternal immune dysregulation seems to affect fetal or postnatal immune development. Preeclampsia is a pregnancy-associated disorder with an immune basis and is linked to atopic disorders in offspring. Here we show reduction of fetal thymic size, alt
Autor:
Izabel Cristina de Matos Andrade, Angélica T. Vieira, Tarcília Aparecida Silva, Soraia Macari, Charles R. Mackay, M.M. Teixeira, S de Oliveira, J.A.A. de Arruda, Gustavo Pompermaier Garlet, Sandra Y. Fukada, Marina Campos Zicker, Marco Aurélio Ramirez Vinolo, Mila Fernandes Moreira Madeira, Letícia Fernanda Duffles, Carina Cristina Montalvany-Antonucci
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Short-chain fatty acids (SCFAs) exert a variety of immune and metabolic functions by binding to G-protein-coupled receptors, mainly free fatty acid receptor 2 (FFAR2). However, the effects of SCFAs and FFARs on bone remodeling, especially in alveolar
Autor:
Willian R. Ribeiro, Mariane Tami Amano, Marcos Antonio Cenedeze, Charles R. Mackay, Caroline M. Ferreira, Rafael Pereira, Vinicius Andrade-Oliveira, Tarcio Teodoro Braga, Danilo Candido de Almeida, Niels Olsen Saraiva Camara, Eliana Mariño, Marco Aurélio Ramirez Vinolo, Meire Ioshie Hiyane, Raphael B. Parmigiani, Remy Robert, Nayara T. S. Doimo, Rildo Aparecido Volpini, Raphael José Ferreira Felizardo, Ingrid Kazue Mizuno Watanabe
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Butyrate is a short-chain fatty acid derived from the metabolism of indigestible carbohydrates by the gut microbiota. Butyrate contributes to gut homeostasis, but it may also control inflammatory responses and host physiology in other tissues. Butyra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f95058ae934523a71be120d784a98118
Autor:
Robert Brink, Charles R. Mackay, Di Yu, Jian Tan, Louis M. Tsai, Katherine Bourne, Alison N. Thorburn, Remy Robert, Linda J. Mason, Nina Chevalier, Connie H.Y. Wong, Laurence Macia
Publikováno v:
Arthritis & Rheumatology. 68:1026-1038
ObjectiveAntibody-mediated autoimmunity involves cognate interactions between self-reactive T cells and B cells during germinal center (GC) reactions. The aim of this study was to determine the role of essential follicular helper T (Tfh) cell molecul
Autor:
Fábio Luiz Dal Moro Maito, Steven R. Kleeberger, Marcio Schmiele, Charles R. Mackay, Emanuelle Fraga da Silva, Laís Passariello Pral, José Eduardo Vargas, Ana Paula de Souza, Jacqui Marzec, José Luís Fachi, Fernando P. Polack, Douglas A. Bell, Fabiana Quoos Mayer, Marcella Ramos Sant'Ana, José Luiz Proença-Módena, Angélica Thomas Vieira, Marco Aurélio Ramirez Vinolo, Rosemeire O. F. de Paula, Hosana G. Rodrigues, Mauricio T. Caballero, Nadim J. Ajami, Renato T. Stein, Renato David Puga, Greicy Dias, Krist Helen Antunes, Carlos R. Zárate-Bladés, Maria Teresa Pedrosa Silva Clerici, Daniel S. Mansur, Xuting Wang, Jianying Li, Thamiris Candreva, Adara Aurea dos Santos
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Severe respiratory syncytial virus (RSV) infection is a major cause of morbidity and mortality in infants
Dietary fibers and SCFAs can exert a protective effect against respiratory syncytial virus (RSV). Here, the authors report that microbiota-
Dietary fibers and SCFAs can exert a protective effect against respiratory syncytial virus (RSV). Here, the authors report that microbiota-
Autor:
Charles R. Mackay, Simon Bulley, Qian Wang, Carlos Fernández-Peña, Kirk W. Evanson, Raquibul Hasan, Jonathan H. Jaggar, M. Dennis Leo, Padmapriya Muralidharan, Sarah K. Burris, Korah P. Kuruvilla
Publikováno v:
Web of Science
Systemic blood pressure is determined, in part, by arterial smooth muscle cells (myocytes). Several Transient Receptor Potential (TRP) channels are proposed to be expressed in arterial myocytes, but it is unclear if these proteins control physiologic