Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Caroline M. Milner"'
Autor:
Anthony J. Day, Douglas P. Dyer, Nikolaos Kouvatsos, Leela C Biant, Jennifer M. Thomson, Caroline M. Milner, Andrew Price, Sanjay Anand, Eckart Bartnik, Jenny L Scott, Matthias Herrmann, Sheona P Drummond, Thomas Leeuw
Publikováno v:
Osteoarthritis and Cartilage.
ObjectivesTo investigate the role of endogenous TSG-6 in human osteoarthritis (OA) and assess the disease-modifying potential of a TSG-6-based biological treatment in cell, explant and animal models of OA.MethodsKnee articular cartilages from OA pati
Autor:
Panayiota Ploutarchou, Anthony J. Day, Agnes A Archibong-Omon, Suzannah A. Williams, Caroline M. Milner, Belinda K M Lo
Publikováno v:
Lo, B K M, Archibong-Omon, A, Ploutarchou, P, Day, A J, Milner, C M & Williams, S A 2018, ' Oocyte-specific ablation of N-And O-glycans alters cumulus cell signalling and extracellular matrix composition ', Reproduction, Fertility and Development . https://doi.org/10.1071/RD18209
Cumulus–oocyte complex (COC) expansion is essential for ovulation and fertilisation and is linked to oocyte quality. Hyaluronan (HA), the major matrix constituent, is cross-linked via inter-α-inhibitor heavy chains (HCs), pentraxin 3 (PTX3) and tu
Autor:
Sally Roberts, S. Griffin, M. T. Bayliss, Helena Evans, Caroline M. Milner, Anthony J. Day, Stephen M. Eisenstein, Jill P. G. Urban, J. Menage, Marilyn S. Rugg
Publikováno v:
European Spine Journal. 14:36-42
Inflammation and irritation of the nerve roots has been indicated as an important factor in the pain associated with symptomatic disc herniations. Tumour necrosis factor alpha (TNFalpha) is now believed to be involved in this pathway. TNFalpha causes
Autor:
Edison Capp, Thomas Strowitzki, Joanna Williams, Ariane Germeyer, Julia Jauckus, Caroline M. Milner, Lena Hauck
Publikováno v:
Archives of gynecology and obstetrics. 289(4)
The human endometrium undergoes repetitive, cyclical changes under the influence of endocrine signals (estrogen and progesterone). In particular, the extensive tissue remodeling, angiogenesis and leukocyte infiltration that occur during decidualizati
Autor:
Mohammed Sharif, David J. Mahoney, Afsie Sabokbar, Nicholas A. Athanasou, Catherine Swales, K Kliskey, Anthony J. Day, Costantino Pitzalis, Michele Bombardieri, Caroline M. Milner
Publikováno v:
Arthritis and rheumatism. 63(4)
Objective TSG-6 (the product of tumor necrosis factor [TNF]–stimulated gene 6) has a potent inhibitory effect on RANKL-mediated bone erosion. The aim of this study was to compare the activity of TSG-6 with that of osteoprotegerin (OPG) and to inves
Autor:
Anthony J. Day, John D. Sandy, Matthew C. Stewart, Marilyn S. Rugg, Y. Yoshihara, K. Nemoto, Fred R.T. Nelson, Caroline M. Milner, Arkady Margulis, Barbara Osborn, Anna Plaas
Publikováno v:
Osteoarthritis and cartilage. 16(11)
Summary Objective We have examined the occurrence of the inflammation-associated inter-alpha-trypsin inhibitor (IαI) components, bikunin, heavy chain (HC)1 and HC2 in normal cartilage and osteoarthritis (OA) cartilage and synovial fluids. Design/met
Autor:
Anthony J. Day, Dafna Benayahu, David J. Mahoney, Caroline M. Milner, Afsie Sabokbar, Guillaume Mabilleau, Katalin Mikecz, T. Ali, Anna Plaas
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2008, 283 (38), pp.25952-25962. ⟨10.1074/jbc.M802138200⟩
The Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2008, 283 (38), pp.25952-25962. ⟨10.1074/jbc.M802138200⟩
The Journal of Biological Chemistry
International audience; TSG-6 is an inflammation-induced protein that is produced at pathological sites, including arthritic joints. In animal models of arthritis, TSG-6 protects against joint damage; this has been attributed to its inhibitory effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b471a4394f347259c357d12950c12613
https://hal.univ-angers.fr/hal-03261996
https://hal.univ-angers.fr/hal-03261996
Publikováno v:
Journal of Reproductive Immunology. 94:65-66
Autor:
Yan Wang, Kazunori Yamaguchi, Ryuzaburo Shineha, Takehito Kato, Caroline M. Milner, Taeko Miyagi, Susumu Satomi
Publikováno v:
International journal of cancer. 92(6)
Increased sialylation in cell surface glycoproteins is one characteristic feature of cancer cells, particularly related to their metastatic potential and invasiveness. Expression of lysosomal-type sialidase, which plays a major role in hydrolysis of
Autor:
Anthony J. Day, Caroline M. Milner, A Sabokbar, Costantino Pitzalis, D.J. Mahoney, Michele Bombardieri, K Kliskey, Catherine Swales, Nicholas A. Athanasou, Mohammed Sharif
Publikováno v:
Bone. 47:S141