Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Carlos López-Larrea"'
Publikováno v:
Trends in Genetics. 38:120-123
The aging process is associated with the accumulation of epigenetic alterations in immune cells, although the origin of these changes is not clear. Understanding this epigenetic drift in the immune system can provide essential information about the p
Autor:
Ramon M. Rodriguez, María P. Hernández-Fuentes, Viviana Corte-Iglesias, María Laura Saiz, Juan José Lozano, Ana R. Cortazar, Isabel Mendizabal, María Luisa Suarez-Fernandez, Eliecer Coto, Antonio López-Vázquez, Carmen Díaz-Corte, Ana M. Aransay, Carlos López-Larrea, Beatriz Suarez-Álvarez
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Operational tolerance after kidney transplantation is defined as stable graft acceptance without the need for immunosuppression therapy. However, it is not clear which cellular and molecular pathways are driving tolerance in these patients. We perfor
Autor:
Aroa Baragaño Raneros, Beatriz Suarez-Alvarez, Ana M. Aransay, José Luis Lavín, David Mosen-Ansorena, Leonardo Márquez-Kisinousky, Ramon M. Rodriguez, Carlos López-Larrea
Publikováno v:
The Journal of Immunology. 198:937-949
Epigenetic mechanisms play a critical role during differentiation of T cells by contributing to the formation of stable and heritable transcriptional patterns. To better understand the mechanisms of memory maintenance in CD8+ T cells, we performed ge
Autor:
Jose Ramón Vidal-Castiñeira, Viviana Corte-Iglesias, Lucia Sobrino-Diaz, Sonia Pérez-Fernández, Santiago Melón, Carlos López-Larrea, Carmen Díaz-Corte
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
WOS:000476743700001
RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Frontiers in Immunology, Vol 10 (2019)
WOS:000476743700001
RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Background: Dialysis is the first procedure to partially replace renal function in end-stage renal diseases, despite several adverse side effects, such as infections. The primary aim of this study was to evaluate the levels of immune CMV-specific CD8
Publikováno v:
Trends in immunology. 40(1)
Infiltrating and tissue-resident myeloid cells are essential regulators of innate and adaptive immunity. During inflammation, and in response to microbial products, these cells can adapt to microenvironmental conditions and acquire specialized functi
Autor:
Edelmiro Menéndez, Beatriz Suarez-Alvarez, Wei Hu, J. Otero, Ruifeng Tang, Silvia Pérez, Eva Martinez Revuelta, Carlos López-Larrea, Huimin Zhou, Edward Guindi, Thomas Moss, Zhenlong Zhu, Jose Maria Garcia-Gala, Elías Delgado, María Álvarez-Viejo, Yong Zhao, Marcos Perez-Basterrechea
Publikováno v:
Scopus
EBioMedicine, Vol 2, Iss 12, Pp 2024-2036 (2015)
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
EBioMedicine
EBioMedicine, Vol 2, Iss 12, Pp 2024-2036 (2015)
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
EBioMedicine
Background Type 1 diabetes (T1D) is a T cell-mediated autoimmune disease that causes a deficit of pancreatic islet β cells. The complexities of overcoming autoimmunity in T1D have contributed to the challenges the research community faces when devis
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 67:75-85
T cell lymphopoiesis is a complex, stepwise process in which the transcriptional program of the progenitor cells is progressively adapted in order to generate mature phenotypes. This transcriptional program in differentiated cells is also very flexib
Autor:
Juan José Lozano, Ana M. Aransay, Aroa Baragaño Raneros, Marcos J. Araúzo-Bravo, José Luis Lavín, Carlos López-Larrea, Beatriz Suarez-Alvarez, Marta Ruiz-Ortega, Covadonga Huidobro, Ana Belen Sanz, Ramon M. Rodriguez, Angel L. Corbí, Paula Díaz Bulnes, Jose Ramón Vidal-Castiñeira, Cristina Martin-Martin, Amaya Puig-Kröger, Monika González, Alex M. Ascensión
Publikováno v:
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Cell Reports, Vol 29, Iss 4, Pp 860-872.e5 (2019)
Biblos-e Archivo: Repositorio Institucional de la UAM
Universidad Autónoma de Madrid
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cell Reports, Vol 29, Iss 4, Pp 860-872.e5 (2019)
Biblos-e Archivo: Repositorio Institucional de la UAM
Universidad Autónoma de Madrid
Digital.CSIC. Repositorio Institucional del CSIC
19 p.-6 fig.
In recent years, the macrophage colony-stimulating factor (M-CSF) and granulocyte-macrophage CSF (GM-CSF) cytokines have been identified as opposing regulators of the inflammatory program. However, the two cytokines are simultaneous
In recent years, the macrophage colony-stimulating factor (M-CSF) and granulocyte-macrophage CSF (GM-CSF) cytokines have been identified as opposing regulators of the inflammatory program. However, the two cytokines are simultaneous
Autor:
Beatriz Tavira, Diego Coronel, Eliecer Coto, Beatriz Suarez, Carlos López-Larrea, Carmen Díaz-Corte, Juan Gómez
Publikováno v:
Journal of Human Genetics. 60:273-276
The ABCB1 gene encodes the P-glycoprotein (P-gp) that drives the transmembrane efflux of many drugs. The donor ABCB1 polymorphisms have been related with chronic histological damage and long-term renal function among kidney transplanted patients who
Autor:
Sandra Rayego-Mateos, Elsa Sanchez-Lopez, Beatriz Suarez-Alvarez, Luiz S. Aroeira, Carolina Lavoz, Matilde Alique, Macarena Orejudo, Marta Ruiz-Ortega, Raquel Rodrigues-Díez, Carlos López-Larrea, Raúl R. Rodrigues-Diez, Jesús Egido, Alberto Ortiz
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
et al.
Connective tissue growth factor (CTGF/CCN2) is a matricellular protein susceptible to proteolytic degradation. CCN2 levels have been suggested as a potential risk biomarker in several chronic diseases. In body fluids, CCN2 full-length and
Connective tissue growth factor (CTGF/CCN2) is a matricellular protein susceptible to proteolytic degradation. CCN2 levels have been suggested as a potential risk biomarker in several chronic diseases. In body fluids, CCN2 full-length and