Zobrazeno 1 - 10
of 2 690
pro vyhledávání: '"Jiang A"'
Publikováno v:
Current Neuropharmacology. 20:1400-1412
The central nervous system (CNS) is enriched with important classes of lipids, in which cholesterol is known to make up a major portion of myelin sheaths, besides being a structural and functional unit of CNS cell membranes. Unlike in the adult brain
Autor:
Yi Pang, Guiyuan Liu, Hui Zhao, Dengxiang Lai, Yi Jiang, Yonghui Zhang, Hongjing Yang, Dan Liu
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 22:851-863
Background: Demethylzeylasteral (ZST93), a pharmacologically active triterpenoid monomer extracted from Tripterygium wilfordii Hook F (TWHF), has been reported to exert antineoplastic effects in several cancer cell types. However, the anti-tumour eff
Publikováno v:
Journal of Cellular and Molecular Medicine
In recent years, a large number of studies have reported that neuroinflammation aggravates the occurrence of secondary injury after spinal cord injury. Gramine (GM), a natural indole alkaloid, possesses various pharmacological properties; however, th
Autor:
Yue Wang, Hong-feng Jiang, Hai-ming Dang, Meng-ru Liu, Xin-yan Liu, Yang Yu, Jiang Xie, Xiao-jun Zhan, Hui-na Zhang, Xiao-fan Wu
Publikováno v:
Cardiovascular Drugs and Therapy. 36:805-815
It has been established that obstructive sleep apnea (OSA) is an independent risk factor for atherosclerosis. Chronic intermittent hypoxia (CIH) activates sympathoadrenal system and upregulates β3 adrenergic receptor (β3 AR). However, the effect of
Autor:
Onur Kanisicak, Hong-Sheng Wang, Jianyong Ma, Hua Zhu, Wei Huang, Jialiang Liang, Ki Ho Park, Zhichao Wu, Christian Paul, Wenfeng Cai, Jianjie Ma, Lin Jiang, Peng Chen, Yigang Wang, Guo-Chang Fan, Meifeng Xu, Liang Niu
Publikováno v:
Molecular Therapy. 30:54-74
Fibroblasts can be reprogrammed into cardiovascular progenitor cells (CPCs) using transgenic approaches, although the underlying mechanism remains unclear. We determined whether activation of endogenous genes such as Gata4, Nkx2.5, and Tbx5 can rapid
Publikováno v:
Current Neuropharmacology. 20:254-266
Background: Default mode network (DMN) is recognized to be involved in generation and propagation of epileptic activities in various epilepsies. Converging evidence has suggested disturbed functional connectivity (FC) in epilepsies, which was inferre
Publikováno v:
Neuroscience. 481:47-59
It is well known that neuroinflammation plays a key role in neurodegenerative diseases. Hypoxia-inducible factor (HIF) and its hydroxylases-Prolyl-4-hydroxyases (PHDs) have been found to modulate the inflammatory processes. Here, the effects of PHDs
Autor:
Xiaoming Wang, Wei-Wei He, Changyue Hou, Xin Zhang, Guohui Jiang, Juming Yu, Jin Yang, Yuan Zhu, Yi Huang, Rong Tu
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 1, Pp 210-216 (2022)
Neural Regeneration Research
Neural Regeneration Research
In Alzheimer's disease and ischemic stroke, intranasal insulin can act as a neuroprotective agent. However, whether intranasal insulin has a neuroprotective effect in intracerebral hemorrhage and its potential mechanisms remain poorly understood. In
Publikováno v:
Current Neuropharmacology. 20:16-26
Two-pore domain potassium (K2P) channels are a diverse family of potassium channels. K2P channels generate background leak potassium currents to regulate cellular excitability and are thereby involved in a wide range of neurological disorders. K2P ch
Autor:
Yu Hu, Weichao Ma, Liang Lyu, Mengmeng Wang, Li Wang, Senlin Yin, Peizhi Zhou, Cheng Chen, Zeming Wang, Yong Jiang, Yueling Zhou, Shu Jiang, Xiujie Wang, Feng Ye
Publikováno v:
Phytotherapy Research. 35:4007-4021
Pituitary adenoma (PA) is a benign intracranial neoplasm originated from pituitary gland. Surgery is the first-line therapy for most of PAs, but lead to unsatisfactory prognosis in some cases. Tetrandrine (Tet) has anticancer effect on some cancers.