Zobrazeno 1 - 10
of 10 878
pro vyhledávání: '"11"'
Autor:
Qiang Niu, Pei Li, Yan Ma, Min-Jun Wang, Li Chen, Hui Cheng, Yi-Ping Hu, Lin Zhuang, Ping Zhu, Xiaoxia Hu, Qian Wang, Changcheng Liu, Miao-Xia He, Hui Jiang, Xiaoping Xu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
At present, all cell strains derived from acute lymphoblastic leukemia (ALL) patients with the long arm of chromosome 11 aberration are accompanied with mixed lineage leukemia (MLL) gene rearrangement. In this study, we established a permanent ALL ce
Autor:
Lisa A. Carey, Patrick L. Leslie, Yvonne L. Chao, Alessandro Porrello, Yi-Hsuan Tsai, Emily B. Harrison, Joel S. Parker, Subrata K. Ghosh, Brian C. Cooley, Chad V. Pecot, Amanda E.D. Van Swearingen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
Nature Communications
Lymph node (LN) metastases correspond with a worse prognosis in nearly all cancers, yet the occurrence of cancer spreading from LNs remains controversial. Additionally, the mechanisms explaining how cancers survive and exit LNs are largely unknown. H
Autor:
Eliza Kwiatkowska-Borowczyk, Anna Kowalik, Andrzej Marszałek, Hanna Dams-Kozlowska, Andrzej Mackiewicz, Sebastian Adamczyk, Ewa Leporowska, Anna Lewandowska, Katarzyna Gryska
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154520 (2016)
PLoS ONE
PLoS ONE
The incidence of cancer is constantly increasing. Chemo/radiotherapy is one of major methods of treating cancer. Although adverse chemo/radiotherapy events, such as anemia and neutropenia, can be successfully cured, thrombocytopenia is still problema
Autor:
Barbara Duff, Andrew M. McIntosh, Nicholas J. Brandon, Neil Roberts, Stephen Giles, Emma Sprooten, Bill Moorhead, Zoë A. Hughes, Jeremy Hall, Pippa A. Thomson, Liana Romaniuk, Scott Semple, Rali Dimitrova, Maria R. Dauvermann, Andrew Watson, Heather C. Whalley, Stephen M. Lawrie, Mark E. Bastin, Brandon Whitcher, John Dunlop, Douglas Blackwood
Publikováno v:
Whalley, H C, Dimitrova, R, Sprooten, E, Dauvermann, MR, Romaniuk, L, Duff, B, Watson, A, Moorhead, B, Bastin, M E, Semple, S, Giles, S, Hall, J, Thomson, P, Roberts, N, Hughes, Z, Brandon, N, Dunlop, J, Whitcher, B, Blackwood, D, McIntosh, A M & Lawrie, S M 2015, ' Effects of a Balanced Translocation between Chromosomes 1 and 11 Disrupting the DISC1 Locus on White Matter Integrity ', PLoS ONE, vol. 10, no. 6, e0130900 . https://doi.org/10.1371/journal.pone.0130900
PLoS ONE
Whalley, H, Dimitrova, R, Sprooten, E, Dauvermann, M R, Romaniuk, L, Duff, B, Watson, A, Moorhead, B, Bastin, M, Semple, S I, Giles, S, Hall, J, Thomson, P, Roberts, N, Hughes, Z, J Brandon, N, Dunlop, J, Whitcher, B, Blackwood, D, McIntosh, A & Lawrie, S 2015, ' Effects of a balanced translocation between chromosomes 1 and 11 disrupting the DISC1 locus on white matter integrity ', PLoS ONE . https://doi.org/10.1371/journal.pone.0130900
PLoS ONE, Vol 10, Iss 6, p e0130900 (2015)
PLoS ONE
Whalley, H, Dimitrova, R, Sprooten, E, Dauvermann, M R, Romaniuk, L, Duff, B, Watson, A, Moorhead, B, Bastin, M, Semple, S I, Giles, S, Hall, J, Thomson, P, Roberts, N, Hughes, Z, J Brandon, N, Dunlop, J, Whitcher, B, Blackwood, D, McIntosh, A & Lawrie, S 2015, ' Effects of a balanced translocation between chromosomes 1 and 11 disrupting the DISC1 locus on white matter integrity ', PLoS ONE . https://doi.org/10.1371/journal.pone.0130900
PLoS ONE, Vol 10, Iss 6, p e0130900 (2015)
Objective\ud \ud Individuals carrying rare, but biologically informative genetic variants provide a unique opportunity to model major mental illness and inform understanding of disease mechanisms. The rarity of such variations means that their study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3234b3519138816c9a70701fe4eacde5
https://kclpure.kcl.ac.uk/ws/files/44357943/pone.0130900.pdf
https://kclpure.kcl.ac.uk/ws/files/44357943/pone.0130900.pdf
Autor:
Alexander Gow, Farhad Ghoddoussi, Shane A. Perrine, Kathleen J. Maheras, Marcello Peppi, Matthew P. Galloway
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Scientific Reports
Scientific Reports
Neuronal origins of behavioral disorders have been examined for decades to construct frameworks for understanding psychiatric diseases and developing useful therapeutic strategies with clinical application. Despite abundant anecdotal evidence for whi
Autor:
Francis G. Szele, Susana Frago, Nicholas B. Davies, Mirvat Surakhy, Martin Ducker, Claudia Bühnemann, Matthew P. Crump, Emma J. Carter, Sermet Can, Roman Trikin, A. Bassim Hassan, Jennifer Hughes
Publikováno v:
Scientific Reports
Hughes, J, Surakhy, M, Can, S, Ducker, M, Davies, N, Szele, F, Bühnemann, C, Carter, E, Trikin, R, Crump, M P, Frago, S & Hassan, A B 2019, ' Maternal transmission of an Igf2r domain 11 : IGF2 binding mutant allele (Igf2r I1565A ) results in partial lethality, overgrowth and intestinal adenoma progression ', Scientific Reports, vol. 9, no. 1, 11388 . https://doi.org/10.1038/s41598-019-47827-9
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Hughes, J, Surakhy, M, Can, S, Ducker, M, Davies, N, Szele, F, Bühnemann, C, Carter, E, Trikin, R, Crump, M P, Frago, S & Hassan, A B 2019, ' Maternal transmission of an Igf2r domain 11 : IGF2 binding mutant allele (Igf2r I1565A ) results in partial lethality, overgrowth and intestinal adenoma progression ', Scientific Reports, vol. 9, no. 1, 11388 . https://doi.org/10.1038/s41598-019-47827-9
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
The cation-independent mannose 6-phosphate/insulin-like growth factor-2 receptor (M6P/IGF2R or IGF2R) traffics IGF2 and M6P ligands between pre-lysosomal and extra-cellular compartments. Specific IGF2 and M6P high-affinity binding occurs via domain-1
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Aging is the biggest risk factor for several neurodegenerative diseases. Parabiosis experiments have established that old mouse brains are improved by exposure to young mouse blood. Previously, our lab showed that delivery of Growth Differentiation F
Autor:
Teresa S. Hawley, Robert G. Hawley, John P. Leonard, Samuel J. Goldman, Mark Collins, Andrew Z. C. Fong, Charlene Quinto
Publikováno v:
Proceedings of the National Academy of Sciences. 93:10297-10302
Based on transplantation studies with bone marrow cultured under various conditions, a role of interleukin 11 (IL-11) in the self-renewal and/or the differentiation commitment of hematopoietic stem cells has been indicated. To better evaluate the in
Autor:
Maryam Tohidi, Yadollah Mehrabi, Atieh Amouzegar, Hossein Delshad, Fereidoun Azizi, M. Gholampour Dehaki
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0184808 (2017)
PLoS ONE
PLoS ONE
Objectives This study aimed to assess the prevalence and incidence and predictive factors of thyroid disorders (TD) in patients with impaired glucose metabolism. Methods Prevalence of TD was calculated in patients with impaired glucose metabolism com
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 5, p e18993 (2011)
PLoS ONE, Vol 6, Iss 5, p e18993 (2011)
BACKGROUND: There is considerable uncertainty about the time-course of central auditory maturation. On some indices, children appear to have adult-like competence by school age, whereas for other measures development follows a protracted course. METH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246108f5cf0d0cccc2e7c51d7593733c
https://ora.ox.ac.uk/objects/uuid:5ee0fec1-3330-4453-9cf8-b00e20db405b
https://ora.ox.ac.uk/objects/uuid:5ee0fec1-3330-4453-9cf8-b00e20db405b